Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation

Article

Madine, J., Wang, X., Brown, D. and Middleton, D. 2009. Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation. ChemBioChem. 10 (12), pp. 1982-1987. https://doi.org/10.1002/cbic.200900219
TypeArticle
TitleEvaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation
AuthorsMadine, J., Wang, X., Brown, D. and Middleton, D.
Abstract

Inhibition of amyoid formation - the β-peptide way: Introducing β-amino acids into short peptides is presented as a novel method of preventing aggregation of amyloid proteins. The data suggest a common precursor to design agents to treat Lewy body disease, Alzheimer's and type 2 diabetes.

PublisherWiley
JournalChemBioChem
ISSN1439-4227
Publication dates
Print2009
Publication process dates
Deposited07 Nov 2013
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.1002/cbic.200900219
LanguageEnglish
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