Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation
Article
Madine, J., Wang, X., Brown, D. and Middleton, D. 2009. Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation. ChemBioChem. 10 (12), pp. 1982-1987. https://doi.org/10.1002/cbic.200900219
| Type | Article |
|---|---|
| Title | Evaluation of β-alanine- and GABA-substituted peptides as inhibitors of disease-linked protein aggregation |
| Authors | Madine, J., Wang, X., Brown, D. and Middleton, D. |
| Abstract | Inhibition of amyoid formation - the β-peptide way: Introducing β-amino acids into short peptides is presented as a novel method of preventing aggregation of amyloid proteins. The data suggest a common precursor to design agents to treat Lewy body disease, Alzheimer's and type 2 diabetes. |
| Publisher | Wiley |
| Journal | ChemBioChem |
| ISSN | 1439-4227 |
| Publication dates | |
| 2009 | |
| Publication process dates | |
| Deposited | 07 Nov 2013 |
| Output status | Published |
| Digital Object Identifier (DOI) | https://doi.org/10.1002/cbic.200900219 |
| Language | English |
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