Vasculogenic mimicry in bladder cancer and its association with cancer stem cells and human chorionic gonadotropin-beta
PhD thesis
Weerasinghe, N. 2022. Vasculogenic mimicry in bladder cancer and its association with cancer stem cells and human chorionic gonadotropin-beta. PhD thesis Middlesex University Natural Sciences
Type | PhD thesis |
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Title | Vasculogenic mimicry in bladder cancer and its association with cancer stem cells and human chorionic gonadotropin-beta |
Authors | Weerasinghe, N. |
Abstract | Bladder cancer is the 11th most common cancer in the United Kingdom and it is the fourth most common cancer in men. It has been found that some cancerous tumours acquire resistance to antiangiogenic therapy due to different angiogenic “escape “ pathways that allow tumours to restore their growth and hence can invade and metastasise. Vascular mimicry is the process of formation of tumour cell lined channels for nutrient transportation, independent of typical modes of angiogenesis. However, not much research has been done to investigate the occurrence of vascular mimicry (VM) in bladder cancer or to correlate the presence of VM with different stages and grades of bladder cancer. Equally, the prevalence of cancer stem cells (CSCs) in bladder cancer in relation to the different grades and stages has not been studied as well as their relationship with VM. |
Sustainable Development Goals | 3 Good health and well-being |
Middlesex University Theme | Health & Wellbeing |
Department name | Natural Sciences |
Institution name | Middlesex University |
Publication dates | |
17 Jan 2023 | |
Publication process dates | |
Deposited | 17 Jan 2023 |
Accepted | 07 Feb 2022 |
Output status | Published |
Language | English |
https://repository.mdx.ac.uk/item/8q3v3
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