Rising ELISPOT count prior to the onset of symptoms of full-blown tuberculosis disease

Article


Adetifa, I.M.O., Brookes, R., Lugos, M., De Jong, B.C., Antonio, M., Adegbola, R.A. and Hill, P.C. 2007. Rising ELISPOT count prior to the onset of symptoms of full-blown tuberculosis disease. International Journal of Tuberculosis and Lung Disease. 11 (3), pp. 350-352.
TypeArticle
TitleRising ELISPOT count prior to the onset of symptoms of full-blown tuberculosis disease
AuthorsAdetifa, I.M.O., Brookes, R., Lugos, M., De Jong, B.C., Antonio, M., Adegbola, R.A. and Hill, P.C.
Abstract

The relationship between the T-cell response to mycobacterial antigens and the likelihood of progression to disease has not been defined. We report a rapidly rising ELISPOT count in a 55-year-old man with evidence of Mycobacterium tuberculosis infection prior to the onset of symptoms of disease. This case illustrates the possible utility of quantitative changes in the ELISPOT count in predicting progression from M. tuberculosis infection to disease.

KeywordsELISPOT; Mycobacterium tuberculosis; tuberculin skin test; tuberculosis
Sustainable Development Goals3 Good health and well-being
Middlesex University ThemeHealth & Wellbeing
PublisherInternational Union Against Tuberculosis and Lung Disease
JournalInternational Journal of Tuberculosis and Lung Disease
ISSN1027-3719
Electronic1815-7920
Publication dates
Print01 Mar 2007
Publication process dates
Submitted27 Aug 2006
Accepted03 Nov 2006
Deposited15 Sep 2026
Output statusPublished
Web address (URL)https://www.ingentaconnect.com/contentone/iuatld/ijtld/2007/00000011/00000003/art00022
Scopus EID2-s2.0-33947396019
Web of Science identifierWOS:000244918500022
Related Output
Has metadatahttp://www.scopus.com/inward/record.url?eid=2-s2.0-33947396019&partnerID=MN8TOARS
LanguageEnglish
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