The impacts of selection pressure on insecticide resistance in malaria vectors – a literature review

Article

Nwinyi, O.C., Farotimi, O.E. and Oluwagbemi, O.O. 2026. The impacts of selection pressure on insecticide resistance in malaria vectors – a literature review. Oriental Insects. https://doi.org/10.1080/00305316.2026.2613387

Publication dates
Type	Article
Title	The impacts of selection pressure on insecticide resistance in malaria vectors – a literature review
Authors	Nwinyi, O.C., Farotimi, O.E. and Oluwagbemi, O.O.
Abstract	Vector control is key to the reduction and elimination of malaria. Indoor residual spraying (IRS), insecticide-treated nets (ITNs), and larviciding are examples of chemical control of malaria vectors. Conversely, the effectiveness of these approaches are currently under threat due to the emergence and global spread of resistance to the four major insecticide classes: pyrethroids, carbamates, organophosphate, and organochlorine. In this review, the mechanisms of resistance to these classes of insecticides include: target site inactivation, metabolic resistance, cuticle thickening, behavioural resistance, and xenobiotic sequestration. Consequently, the excessive use of insecticides, as well as other environmental factors such as agriculture, microbiome, natural xenobiotics, climatic factors, edaphic factors, and anthropogenic activities, have created selective pressure that constantly drives the emergence and intensification of insecticide resistance among Anopheles mosquitoes.
Sustainable Development Goals	15 Life on land
	3 Good health and well-being
Middlesex University Theme	Health & Wellbeing
Publisher	Taylor & Francis (Routledge)
Journal	Oriental Insects
ISSN	0030-5316
Electronic	2157-8745
Online	28 Jan 2026
Publication process dates
Submitted	29 Mar 2025
Accepted	04 Jan 2026
Deposited	09 Feb 2026
Output status	Published
Digital Object Identifier (DOI)	https://doi.org/10.1080/00305316.2026.2613387

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