Polyoma virus middle T antigen and its role in identifying cancer-related molecules
Article
Dilworth, S. 2002. Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nature Reviews Cancer. 2 (12), pp. 951-956. https://doi.org/10.1038/nrc946
Type | Article |
---|---|
Title | Polyoma virus middle T antigen and its role in identifying cancer-related molecules |
Authors | Dilworth, S. |
Abstract | Most cancer researchers take for granted some of the basic concepts about the molecular changes that underlie tumorigenesis. These include the principles that tyrosine kinases and the phosphorylation of phosphatidylinositol by phosphatidylinositol 3-kinases are important in the signalling pathways that control proliferation and apoptosis, and hence cancer formation. However, how many know that a small DNA mouse virus was crucial in establishing both of these tenets? |
Research Group | Molecular Biology group |
Publisher | Nature Publishing Group |
Journal | Nature Reviews Cancer |
ISSN | 1474-175X |
Publication dates | |
Dec 2002 | |
Publication process dates | |
Deposited | 19 Feb 2013 |
Output status | Published |
Digital Object Identifier (DOI) | https://doi.org/10.1038/nrc946 |
Language | English |
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