Differences between diurnal patterns of salivary cortisol and dehydroepiandrosterone in healthy female adolescents

Article


Oskis, A., Clow, A., Thorn, L., Loveday, C. and Hucklebridge, F. 2012. Differences between diurnal patterns of salivary cortisol and dehydroepiandrosterone in healthy female adolescents. Stress. 15 (1), pp. 110-114. https://doi.org/10.3109/10253890.2011.582529
TypeArticle
TitleDifferences between diurnal patterns of salivary cortisol and dehydroepiandrosterone in healthy female adolescents
AuthorsOskis, A., Clow, A., Thorn, L., Loveday, C. and Hucklebridge, F.
Abstract

The adrenal hormones cortisol and dehydroepiandrosterone (DHEA) share a common secretagogue: adrenocorticotropic hormone; however, secretion of these hormones can be dissociated suggesting subtle individual regulation at the level of the adrenal gland. We examined differences in the diurnal patterns of cortisol and DHEA secretion in healthy adolescent girls, with the aim of informing the possibility of exploiting these differences to aid interpretation of data from clinical populations in which these patterns can become dysregulated. Fifty-six healthy females aged 10–18 years provided saliva samples at 0 and 30 min (morning samples) and 12 h post-awakening on 2 consecutive weekdays. For morning salivary cortisol in relation to morning DHEA concentrations, correlational analysis revealed only a trend (p = 0.054). Similarly, the association between evening cortisol and DHEA was characterised as a trend (p = 0.084). Mean morning DHEA concentrations showed more day-to-day consistency than equivalent cortisol samples (r = 0.829 for DHEA and 0.468 for cortisol; z = 3.487, p < 0.0005). Unlike the cortisol pattern, characterised by a marked awakening response (cortisol awakening response, CAR), a significant rise in DHEA concentration post-awakening was not evident. Finally, there was a strong association between morning and evening concentrations of DHEA, not found for cortisol. The study shows differences in cortisol and DHEA secretion in the post-awakening period and informs work that seeks to examine correlates of dysregulated hypothalamic–pituitary–adrenal axis function. Parallel examination of both hormones enables enhanced interpretation of aberrant patterns of the CAR, i.e. an exploration of whether dysregulation affects both hormones (reflecting overall steroidogenic capacity) or cortisol alone (CAR-specific mechanisms).

PublisherTaylor and Francis
JournalStress
ISSN1025-3890
Publication dates
Online26 Jul 2011
Print01 Jan 2012
Publication process dates
Deposited27 Mar 2017
Accepted15 Apr 2011
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.3109/10253890.2011.582529
LanguageEnglish
Permalink -

https://repository.mdx.ac.uk/item/86y07

  • 24
    total views
  • 0
    total downloads
  • 2
    views this month
  • 0
    downloads this month

Export as

Related outputs

"My heart and my brain is what's bleeding, these are just cuts." An interpretative phenomenological analysis of young women's experiences of self-harm
Norman, H., Marzano, L., Oskis, A. and Coulson, M. 2022. "My heart and my brain is what's bleeding, these are just cuts." An interpretative phenomenological analysis of young women's experiences of self-harm. Frontiers in Psychiatry. 13, pp. 1-7. https://doi.org/10.3389/fpsyt.2022.914109
Parenting adolescent daughters: differential effects of maternal attachment insecurity and proximity-seeking
Oskis, A., Thorn, L. and Clow, A. 2022. Parenting adolescent daughters: differential effects of maternal attachment insecurity and proximity-seeking. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 24 (1), pp. 69-86. https://doi.org/10.3280/MAL2022-001005
"I can’t describe it and they can’t see the rain." an interpretative phenomenological analysis of the experience of self-harm in young adults who report difficulties identifying and describing their feelings
Norman, H., Marzano, L., Oskis, A. and Coulson, M. 2023. "I can’t describe it and they can’t see the rain." an interpretative phenomenological analysis of the experience of self-harm in young adults who report difficulties identifying and describing their feelings. Current Psychology. 42 (12), pp. 10151-10162. https://doi.org/10.1007/s12144-021-02273-7
MasterChef: a Master class in fight, flight, or flambé?
Oskis, A. 2021. MasterChef: a Master class in fight, flight, or flambé? Gastronomica. 21 (1), pp. 58-64. https://doi.org/10.1525/gfc.2021.21.1.58
The relationship between alexithymia and self-harm: the mediating role of mindfulness
Norman, H., Marzano, L., Oskis, A. and Coulson, M. 2021. The relationship between alexithymia and self-harm: the mediating role of mindfulness. Current Psychology. https://doi.org/10.1007/s12144-021-01553-6
The child attachment style interview (Child-ASI) and depression: preliminary findings
Bifulco, A., Jacobs, C., Oskis, A., Bunn, A. and Spence, R. 2021. The child attachment style interview (Child-ASI) and depression: preliminary findings. Educational and Child Psychology. 38 (1), pp. 62-74.
Associations between adult attachment and vision-related quality of life in visually impaired individuals
Ctori, I., Ahmad, S., Subramanian, A. and Oskis, A. 2020. Associations between adult attachment and vision-related quality of life in visually impaired individuals. Psychology, Health & Medicine. https://doi.org/10.1080/13548506.2020.1778749
Assessing parenting in potentially abusive parents: a qualitative evaluation of practitioner responses to the parenting role interview
Barry, R., Edwards, S., Oskis, A. and Carraro, E. 2019. Assessing parenting in potentially abusive parents: a qualitative evaluation of practitioner responses to the parenting role interview. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 21 (3), pp. 39-53. https://doi.org/10.3280/MAL2019-003004
Caregiving and care seeking as predictors of depression in girls: a pilot study of parenting in mother-daughter dyads
Oskis, A., Thorn, L. and Clow, A. 2019. Caregiving and care seeking as predictors of depression in girls: a pilot study of parenting in mother-daughter dyads. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 21 (3), pp. 11-21. https://doi.org/10.3280/MAL2019-003002
The relationship between self-harm and alexithymia: a systematic review and meta-analysis
Norman, H., Oskis, A., Marzano, L. and Coulson, M. 2020. The relationship between self-harm and alexithymia: a systematic review and meta-analysis. Scandinavian Journal of Psychology. 61 (6), pp. 855-876. https://doi.org/10.1111/sjop.12668
Lifetime trauma, adversity and emotional disorder in older age women
Bifulco, A., Jacobs, C., Oskis, A., Cavana, F. and Spence, R. 2019. Lifetime trauma, adversity and emotional disorder in older age women. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 21 (2), pp. 29-43. https://doi.org/10.3280/mal2019-002003
Tourism, migration, and the exodus to virtual worlds: place attachment in massively multiplayer online gamers
Coulson, M., Oskis, A., Spencer, R. and Gould, R. 2020. Tourism, migration, and the exodus to virtual worlds: place attachment in massively multiplayer online gamers. Psychology of Popular Media. 9 (4), pp. 525-532. https://doi.org/10.1037/ppm0000244
Using the attachment style interview to explore non-suicidal self-injury in men: the representational pathway from childhood trauma to non-suicidal self-injury
Oskis, A. and Borrill, J. 2019. Using the attachment style interview to explore non-suicidal self-injury in men: the representational pathway from childhood trauma to non-suicidal self-injury. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 21 (1), pp. 23-37. https://doi.org/10.3280/MAL2019-001003
Attachment style and alexithymia as predictors of non-suicidal self-injury in young adults: a pilot study
Oskis, A. and Borrill, J. 2019. Attachment style and alexithymia as predictors of non-suicidal self-injury in young adults: a pilot study. Maltrattamento E Abuso All’infanzia: Rivista Interdisciplinare. 21 (1), pp. 11-21. https://doi.org/10.3280/MAL2019-001002
Repressors exhibit lower cortisol reactivity to group psychosocial stress
Oskis, A., Smyth, N., Flynn, M. and Clow, A. 2019. Repressors exhibit lower cortisol reactivity to group psychosocial stress. Psychoneuroendocrinology. 103, pp. 33-40. https://doi.org/10.1016/j.psyneuen.2018.12.220
Effects of mindfulness-based interventions on alexithymia: a systematic review
Norman, H., Marzano, L., Coulson, M. and Oskis, A. 2018. Effects of mindfulness-based interventions on alexithymia: a systematic review. Evidence-Based Mental Health. https://doi.org/10.1136/ebmental-2018-300029
Attachment, attraction and communication in real and virtual worlds: a study of massively multiplayer online gamers
Coulson, M., Oskis, A., Meredith, J. and Gould, R. 2018. Attachment, attraction and communication in real and virtual worlds: a study of massively multiplayer online gamers. Computers in Human Behavior. 87, pp. 49-57. https://doi.org/10.1016/j.chb.2018.05.017
Avoidance of the real and anxiety about the unreal: attachment style and video-gaming
Coulson, M., Oskis, A. and Gould, R. 2017. Avoidance of the real and anxiety about the unreal: attachment style and video-gaming. Contemporary Issues in Early Childhood. 18 (2), pp. 240-249. https://doi.org/10.1177/1463949117714085
The application of a qualitative approach to adult attachment research: a short report
Bailey-Rodriguez, D., Frost, N. and Oskis, A. 2016. The application of a qualitative approach to adult attachment research: a short report. Quarterly.
Adolescent attachment style in residential care: the attachment style interview and vulnerable attachment style questionnaire
Bifulco, A., Jacobs, C., Ilan-Clarke, Y., Spence, R. and Oskis, A. 2017. Adolescent attachment style in residential care: the attachment style interview and vulnerable attachment style questionnaire. The British Journal of Social Work. 47 (7), pp. 1870-1883. https://doi.org/10.1093/bjsw/bcw117
Biological stress regulation in female adolescents: a key role for confiding
Oskis, A., Clow, A., Loveday, C., Hucklebridge, F. and Sbarra, D. 2015. Biological stress regulation in female adolescents: a key role for confiding. Journal of Youth and Adolescence. 44 (5), pp. 1066-1077. https://doi.org/10.1007/s10964-014-0182-z
Anxious attachment style predicts an enhanced cortisol response to group psychosocial stress
Smyth, N., Thorn, L., Oskis, A., Hucklebridge, F., Evans, P. and Clow, A. 2015. Anxious attachment style predicts an enhanced cortisol response to group psychosocial stress. Stress. 18 (2), pp. 143-148. https://doi.org/10.3109/10253890.2015.1021676
Understanding alexithymia in female adolescents: the role of attachment style
Oskis, A., Clow, A., Hucklebridge, F., Bifulco, A., Jacobs, C. and Loveday, C. 2013. Understanding alexithymia in female adolescents: the role of attachment style. Personality and Individual Differences. 54 (1), pp. 97-102. https://doi.org/10.1016/j.paid.2012.08.023
Diurnal patterns of salivary cortisol across the adolescent period in healthy females
Oskis, A., Loveday, C., Hucklebridge, F., Thorn, L. and Clow, A. 2009. Diurnal patterns of salivary cortisol across the adolescent period in healthy females. Psychoneuroendocrinology. 34 (3), pp. 307-316. https://doi.org/10.1016/j.psyneuen.2008.09.009
Recovery from adolescent anorexia nervosa and associations with diurnal patterns of salivary stress hormones: a case report
Oskis, A., Loveday, C., Hucklebridge, F., Wood, D. and Clow, A. 2012. Recovery from adolescent anorexia nervosa and associations with diurnal patterns of salivary stress hormones: a case report. Case Reports in Psychiatry. 2012, pp. 1-7. https://doi.org/10.1155/2012/798512
Diurnal patterns of salivary cortisol and DHEA in adolescent anorexia nervosa
Oskis, A., Loveday, C., Hucklebridge, F., Thorn, L. and Clow, A. 2012. Diurnal patterns of salivary cortisol and DHEA in adolescent anorexia nervosa. Stress. 15 (6), pp. 601-607. https://doi.org/10.3109/10253890.2012.661493
Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents
Oskis, A., Loveday, C., Hucklebridge, F., Thorn, L. and Clow, A. 2010. Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents. Journal of Child Psychology and Psychiatry. 52 (2), pp. 111-118. https://doi.org/10.1111/j.1469-7610.2010.02296.x