Dr Thamarai Janganan
| Name | Dr Thamarai Janganan |
|---|---|
| Job title | Senior Lecturer in Medical Microbiology |
| Research institute | |
| Primary appointment | Natural Sciences |
| Email address | t.janganan@mdx.ac.uk |
| ORCID | https://orcid.org/0000-0002-2771-2134 |
| Contact category | Academic staff |
Biography
Biography
Thamarai (Tham) Kannan Janganan is a Senior Lecturer in Medical Microbiology at the Department of Natural Sciences at Middlesex University, London. Thamarai's research focuses on 'Antimicrobial Resistance (AMR)', particularly in Multi-Drug Efflux pumps. He
is a trained Microbiologist, who has worked as a Clinical Microbiologist and
Lecturer at various higher education institutions and hospitals in India since
1995. Later, he moved to the UK and received his PhD in Molecular Microbiology from Durham University in 2008. Following this, he held senior post-doctoral positions at Durham, Sheffield and Essex Universities and subsequently worked as a Lecturer in Microbiology at the University of Bedfordshire before moving
to Middlesex University.
Thamarai is currently a member of the reviewer board of MDPI journals Antibiotics, Pathogens and Microorganisms, a member of the Microbiology Society, UK and a fellow
of the Higher Education Academy (FHEA), UK. Having passion and enthusiasm for teaching and supporting students learning, he has been nominated for the Student-Led Teaching Award 2023 at Middlesex University. He has successfully supervised a number of PG projects in the areas AMR.
Teaching
Programme Leadership:
Thamarai is the Programme Leader for MSc
Biomedical Science (Medical Microbiology) and BSc Applied Biomedical Science. He collaborates with external clinical placement providers to support Applied Biomedical Science students' IBMS training Portfolio, such as Health Service Laboratories (HSL), The Doctors Laboratory (TDL), Health Care Laboratories (HCA) and NHS BT. He also chairs the Employer/ IBMS Trainers Liaison group meeting to share feedback on the placement experience.
Modules taught:
-BMS4417 Infectious agents,
BMS4427, Human infectious diseases, BMS4437, Control of Infectious Diseases and
BMS 4447 Diagnosis of Infectious diseases and Safety for MSc Medical Medical
Microbiology.
-BMS3346 Medical
Microbiology for 3rd-year Biomedical Science Programme
-BMS 2145 Infection and
Immunity for 2nd year Biomedical Science programme.
Curriculum Development:
Developed a number of
modules and teaching materials for microbiology-related modules for UG and MSc
programmes.
Actively involved in a number of Programme revalidation and re-accreditation events at various HEIs.
Employment
Education and qualifications
Grants
Prizes and Awards
Student-Led Teaching Award- runners
2023-03-01
Middlesex University
External activities
Evaluate PhD thesis as an external examiner.
Research outputs
Genome sequence of the biocontrol agent Coniothyrium minitans Conio (IMI 134523)
Patel, D., Shittu, T.A., Baroncelli, R., Muthumeenakshi, S., Osborne, T.H., Janganan, T. and Sreenivasaprasad, S. 2021. Genome sequence of the biocontrol agent Coniothyrium minitans Conio (IMI 134523). Molecular Plant-Microbe Interactions. 34 (2), pp. 222-225. https://doi.org/10.1094/MPMI-05-20-0124-AArchitecture and self-assembly of Clostridium sporogenes and Clostridium botulinum spore surfaces illustrate a general protective strategy across spore formers
Janganan, T.K.,, Mullin, N., Dafis-Sagarmendi, A., Brunt, J., Tzokov, S.B., Stringer, S., Moir, A., Chaudhuri, R.R., Fagan, R.P., Hobbs, J.K. and Bullough, P.A. 2020. Architecture and self-assembly of Clostridium sporogenes and Clostridium botulinum spore surfaces illustrate a general protective strategy across spore formers. mSphere. 5 (4). https://doi.org/10.1128/msphere.00424-20ATP-binding cassette transporter VcaM from Vibrio cholerae is dependent on the outer membrane factor family for its function
Lu, W.J., Lin, H.J., Janganan, T.K., Li, C.Y., Chin, W.C., Bavro, V.N. and Lin, H.T.V. 2018. ATP-binding cassette transporter VcaM from Vibrio cholerae is dependent on the outer membrane factor family for its function. International Journal of Molecular Sciences. 19 (4). https://doi.org/10.3390/ijms19041000Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains
Janganan, T.K., Mullin, N., Stringer, S., Fagan, R.P., Hobbs, J.K., Moir, A. and Bullough, P.A. 2016. Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains. Food Microbiology. 59, pp. 205-212. https://doi.org/10.1016/j.fm.2016.06.003A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes
Janganan T.K., Chen, G., Chen, D., Menino, J.F., Rodrigues, F., Borges-Walmsley, M.I. and Walmsley, A.R. 2015. A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes. PLoS ONE. 10 (9). https://doi.org/10.1371/journal.pone.0136866Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump
Janganan T.K., Bavro, V.N., Zhang, L., Borges-Walmsley, M.I. and Walmsley, A.R. 2013. Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Molecular Microbiology. 88 (3), pp. 590-602. https://doi.org/10.1111/mmi.12211The regulation of the CAMP signalling pathway in the human pathogenic fungus, Paracoccidioides brasiliensis
Janganan, T.K. 2008. The regulation of the CAMP signalling pathway in the human pathogenic fungus, Paracoccidioides brasiliensis. PhD thesis Durham University School of BiosciencesEvidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3: 6: 3
Janganan T.K., Bavro, V.N., Zhang, L., Vinkovic, D.M., Barrera, N.P., Robinson, C.V., Borges-Walmsley, M.I. and Walmsley, A.R. 2011. Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3: 6: 3. Journal of Biological Chemistry. 286 (30), pp. 26900-26912. https://doi.org/10.1074/jbc.M111.246595AlsOpening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner
Janganan, T.K., Zhang, L., Barrera, N.P., Bavro, V.N., Vinkovic, D.M., Robinson, C.V., Borges-Walmsley, M.I. and Walmsley, A.R. 2011. Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner. Journal of Biological Chemistry. 286 (7), pp. 5484-5493. https://doi.org/10.1074/jbc.M110.187658The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis
Chen, D., Janganan, T.K., Chen, G., Marques, E.R., Kress, M.R., Goldman, G.H., Walmsley, A.R. and Borges-Walmsley, M.I. 2007. The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis. Molecular Microbiology. 65 (3), pp. 761-779. https://doi.org/10.1111/j.1365-2958.2007.05824.x60
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