Dr Thamarai Janganan


Dr Thamarai Janganan
NameDr Thamarai Janganan
Job titleSenior Lecturer in Medical Microbiology
Research institute
Primary appointmentNatural Sciences
Email addresst.janganan@mdx.ac.uk
ORCIDhttps://orcid.org/0000-0002-2771-2134
Contact categoryAcademic staff

Biography

Biography

Thamarai (Tham) Kannan Janganan is a Senior Lecturer in Medical Microbiology at the Department of Natural Sciences at Middlesex University, London. He is a trained Microbiologist, who has worked as a Clinical Microbiologist and Lecturer at various higher education institutions and hospitals in India since 1995. Later, he moved to the UK and received his PhD in Molecular Microbiology from Durham University in 2008. Following this, he held senior post-doctoral positions at Durham, Sheffield and Essex Universities and subsequently worked as a Lecturer in Microbiology at the University of Bedfordshire before moving to Middlesex University.

Thamarai is currently a member of the reviewer board of MDPI journals Antibiotics, Pathogens and Microorganisms, a member of the Microbiology Society, UK and a fellow of the Higher Education Academy (FHEA), UK.

Having passion and enthusiasm for teaching and supporting students learning, he has been nominated for the Student-Led Teaching Award 2023 at Middlesex University.

He has successfully supervised around 25 PG projects in the areas of 'Antimicrobial Resistance' (AMR).

Teaching

Programme Leadership:

Thamarai is the Programme Leader for MSc Biomedical Science (Medical Microbiology) and BSc Applied Biomedical Science. He collaborates with external clinical placement providers to support Applied Biomedical Science students' IBMS training Portfolio, such as Health Service Laboratories (HSL), The Doctors Laboratory (TDL), Health Care Laboratories (HCA) and NHS BT. He also chairs the Employer/ IBMS Trainers Liaison group meeting to share feedback on the placement experience.

Modules taught:

-BMS4417 Infectious agents, BMS4427, Human infectious diseases, BMS4437, Control of Infectious Diseases and BMS 4447 Diagnosis of Infectious diseases and Safety for MSc Medical Medical Microbiology.

-BMS3346 Medical Microbiology for 3rd-year Biomedical Science Programme

-BMS 2145 Infection and Immunity for 2nd year Biomedical Science programme.

Curriculum Development:

Developed a number of modules and teaching materials for microbiology-related modules for UG and MSc programmes. 

Actively involved in a number of Programme revalidation and re-accreditation events at various HEIs.

Employment

Senior Lecturer in Medical Microbiology
Middlesex University
22 Aug 2022
Lecturer in Microbiology and Biotechnology
University of Bedfordshire
17 Nov 2017
22 Aug 2022
Senior Research Fellow
Essex University
01 Jun 2016
17 Aug 2017
Senior Research Fellow
University of Sheffield
20 Aug 2011
30 May 2016
Research Associate
Durham University
01 Nov 2008
17 Aug 2011
Clinical Microbiologist/Visiting consultant Microbiologist/Lecturer
Various Hospitals -India
01 Sept 1996
01 Jan 2005

Education and qualifications

PHD Molecular Microbiology
06 Nov 2008
Durham University
PGCAP
01 Jan 2010
Durham University
MSc Microbiology
01 Apr 1995
Madurai Kamaraj University
BSc Chemistry with Biology
01 Apr 1993
Madurai Kamaraj University

Grants

Prizes and Awards

External activities

Reviewer Board member of Journals: Antibiotics, Pathogen and Microorganisms
External peer-reviewer
MDPI
01 Nov 2017

Promotion Board/panel member
External reviewer

Reviewer
External independent reviewer for funding applications
BBSRC grant Applications

Research outputs

Genome sequence of the biocontrol agent Coniothyrium minitans Conio (IMI 134523)

Patel, D., Shittu, T.A., Baroncelli, R., Muthumeenakshi, S., Osborne, T.H., Janganan, T. and Sreenivasaprasad, S. 2021. Genome sequence of the biocontrol agent Coniothyrium minitans Conio (IMI 134523). Molecular Plant-Microbe Interactions. 34 (2), pp. 222-225. https://doi.org/10.1094/MPMI-05-20-0124-A

Architecture and self-assembly of Clostridium sporogenes and Clostridium botulinum spore surfaces illustrate a general protective strategy across spore formers

Janganan, T.K.,, Mullin, N., Dafis-Sagarmendi, A., Brunt, J., Tzokov, S.B., Stringer, S., Moir, A., Chaudhuri, R.R., Fagan, R.P., Hobbs, J.K. and Bullough, P.A. 2020. Architecture and self-assembly of Clostridium sporogenes and Clostridium botulinum spore surfaces illustrate a general protective strategy across spore formers. mSphere. 5 (4). https://doi.org/10.1128/msphere.00424-20

ATP-binding cassette transporter VcaM from Vibrio cholerae is dependent on the outer membrane factor family for its function

Lu, W.J., Lin, H.J., Janganan, T.K., Li, C.Y., Chin, W.C., Bavro, V.N. and Lin, H.T.V. 2018. ATP-binding cassette transporter VcaM from Vibrio cholerae is dependent on the outer membrane factor family for its function. International Journal of Molecular Sciences. 19 (4). https://doi.org/10.3390/ijms19041000

Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains

Janganan, T.K., Mullin, N., Stringer, S., Fagan, R.P., Hobbs, J.K., Moir, A. and Bullough, P.A. 2016. Characterization of the spore surface and exosporium proteins of Clostridium sporogenes; implications for Clostridium botulinum group I strains. Food Microbiology. 59, pp. 205-212. https://doi.org/10.1016/j.fm.2016.06.003

A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes

Janganan T.K., Chen, G., Chen, D., Menino, J.F., Rodrigues, F., Borges-Walmsley, M.I. and Walmsley, A.R. 2015. A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes. PLoS ONE. 10 (9). https://doi.org/10.1371/journal.pone.0136866

Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump

Janganan T.K., Bavro, V.N., Zhang, L., Borges-Walmsley, M.I. and Walmsley, A.R. 2013. Tripartite efflux pumps: energy is required for dissociation, but not assembly or opening of the outer membrane channel of the pump. Molecular Microbiology. 88 (3), pp. 590-602. https://doi.org/10.1111/mmi.12211

The regulation of the CAMP signalling pathway in the human pathogenic fungus, Paracoccidioides brasiliensis

Janganan, T.K. 2008. The regulation of the CAMP signalling pathway in the human pathogenic fungus, Paracoccidioides brasiliensis. PhD thesis Durham University School of Biosciences

Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3: 6: 3

Janganan T.K., Bavro, V.N., Zhang, L., Vinkovic, D.M., Barrera, N.P., Robinson, C.V., Borges-Walmsley, M.I. and Walmsley, A.R. 2011. Evidence for the assembly of a bacterial tripartite multidrug pump with a stoichiometry of 3: 6: 3. Journal of Biological Chemistry. 286 (30), pp. 26900-26912. https://doi.org/10.1074/jbc.M111.246595Als

Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner

Janganan, T.K., Zhang, L., Barrera, N.P., Bavro, V.N., Vinkovic, D.M., Robinson, C.V., Borges-Walmsley, M.I. and Walmsley, A.R. 2011. Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner. Journal of Biological Chemistry. 286 (7), pp. 5484-5493. https://doi.org/10.1074/jbc.M110.187658

The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis

Chen, D., Janganan, T.K., Chen, G., Marques, E.R., Kress, M.R., Goldman, G.H., Walmsley, A.R. and Borges-Walmsley, M.I. 2007. The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis. Molecular Microbiology. 65 (3), pp. 761-779. https://doi.org/10.1111/j.1365-2958.2007.05824.x
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