Electrochemical isothiocyanation of primary amines

Article

Kiaku, C., Walsh, J.M., Leech, M.C., Poole, D.L., Mason, J., Goodall, I.C.A., Devo, P. and Lam, K. 2023. Electrochemical isothiocyanation of primary amines. Organic Letters. 25 (7), pp. 1147-1150. https://doi.org/10.1021/acs.orglett.3c00128
TypeArticle
TitleElectrochemical isothiocyanation of primary amines
AuthorsKiaku, C., Walsh, J.M., Leech, M.C., Poole, D.L., Mason, J., Goodall, I.C.A., Devo, P. and Lam, K.
Abstract

Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical, mild, high-yielding, and supporting-electrolyte-free electrochemical method for the preparation of aliphatic and aromatic isothiocyanates from amine and carbon disulfide.

KeywordsAmines; Desulfurization; Disulfides; Electrodes; Salts
Sustainable Development Goals12 Responsible consumption and production
Middlesex University ThemeSustainability
PublisherAmerican Chemical Society (ACS)
JournalOrganic Letters
ISSN1523-7060
Electronic1523-7052
Publication dates
Online14 Feb 2023
Print24 Feb 2023
Publication process dates
Submitted12 Jan 2023
Deposited02 Jun 2025
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.1021/acs.orglett.3c00128
Web of Science identifierWOS:000933929300001
Related Output
Has versionhttps://gala.gre.ac.uk/id/eprint/38568/
Permalink -

https://repository.mdx.ac.uk/item/1q1xw2

Log in to edit
Fetching citation counts from Clarivate.
  • 4
    total views
  • 0
    total downloads
  • 4
    views this month
  • 0
    downloads this month

Export as

Related outputs

An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS).
Devo, P., Cretu, V., Radhakrishnan, H., Hamilton-Pink, D., Boussios, S. and Ovsepian, S. 2024. An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS). Journal of Neural Transmission. https://doi.org/10.1007/s00702-024-02862-3
Ageing perspective on cognitive outcomes from ancillary reproductive hormone adjustments
Zhang, G., Devo, P., O'Leary, V.B. and Ovsepian, S.V. 2023. Ageing perspective on cognitive outcomes from ancillary reproductive hormone adjustments. Heliyon. 9 (8). https://doi.org/10.1016/j.heliyon.2023.e19050
Exosomes in the diagnosis and treatment of renal cell cancer
Boussios, S., Devo, P., Goodall, I.C.A., Sirlantzis, K., Ghose, A., Shinde, S.D., Papadopoulos, V., Sanchez, E., Rassy, E. and Ovsepian, S.V. 2023. Exosomes in the diagnosis and treatment of renal cell cancer. International Journal of Molecular Sciences. 24 (18). https://doi.org/10.3390/ijms241814356
eFluorination using cheap and readily available tetrafluoroborate salts
Leech, M.C., Nagornii, D., Walsh, J.M., Kiaku, C., Poole, D.L., Mason, J., Goodall, I.C.A., Devo, P. and Lam, K. 2023. eFluorination using cheap and readily available tetrafluoroborate salts. Organic Letters. 25 (9), p. 1353–1358. https://doi.org/10.1021/acs.orglett.2c04305
eFluorination of activated alcohols using collidinium tetrafluoroborate
Kiaku, C., Martinage, D., Sicim, Y., Leech, M.C., Walsh, J.M., Poole, D.L., Mason, J., Goodall, I.C.A., Devo, P. and Lam, K. 2023. eFluorination of activated alcohols using collidinium tetrafluoroborate. Organic Letters. 26 (14), pp. 2697-2701. https://doi.org/10.1021/acs.orglett.3c00976
eHydrogenation: hydrogen-free electrochemical hydrogenation
Russo, C., Leech, M.C., Walsh, J.M., Higham, J.I., Giannessi, L., Lambert, E., Kiaku, C., Poole, D.L., Mason, J., Goodall, C.A.I., Devo, P., Giustiniano, M., Radi, M. and Lam, K. 2023. eHydrogenation: hydrogen-free electrochemical hydrogenation. Angewandte Chemie International Edition. 62 (38). https://doi.org/10.1002/anie.202309563
Synthesis of N-Glucosyl Ethyl and Butyl Phosphoramidates
Subratti, A., Jalsa, N.K. and Devo, P. 2021. Synthesis of N-Glucosyl Ethyl and Butyl Phosphoramidates. in: Kosma, P., Wrodnigg, T.M. and Stütz, A. (ed.) Carbohydrate chemistry: Proven synthetic methods, volume 5 CRC Press. pp. 37-42