Mechanically robust and transparent N-Halamine grafted PVA-co-PE films with renewable antimicrobial activity

Article


Si, Y., Cossu, A., Nitin, N., Ma, Y., Zhao, C., Chiou, B., Cao, T., Wang, D. and Sun, G. 2017. Mechanically robust and transparent N-Halamine grafted PVA-co-PE films with renewable antimicrobial activity. Macromolecular Bioscience. 17 (3). https://doi.org/10.1002/mabi.201600304
TypeArticle
TitleMechanically robust and transparent N-Halamine grafted PVA-co-PE films with renewable antimicrobial activity
AuthorsSi, Y., Cossu, A., Nitin, N., Ma, Y., Zhao, C., Chiou, B., Cao, T., Wang, D. and Sun, G.
Abstract

Antimicrobial polymeric films that are both mechanically robust and function renewable would have broad technological implications for areas ranging from medical safety and bioengineering to foods industry; however, creating such materials has proven extremely challenging. Here, a novel strategy is reported to create high‐strength N‐halamine incorporated poly(vinyl alcohol‐co‐ethylene) films (HAF films) with renewable antimicrobial activity by combining melt radical graft polymerization and reactive extrusion technique. The approach allows here the intrinsically rechargeable N‐halamine moieties to be covalently incorporated into polymeric films with high biocidal activity and durability. The resulting HAF films exhibit integrated properties of robust mechanical strength, high transparency, rechargeable chlorination capability (>300 ppm), and long‐term durability, which can effectively offer 3–5 logs CFU reduction against typical pathogenic bacterium Escherichia coli within a short contact time of 1 h, even at high organism conditions. The successful synthesis of HAF films also provides a versatile platform for exploring the applications of antimicrobial N‐halamine moieties in a self‐supporting, structurally adaptive, and function renewable form.

Keywordsantimicrobial; medical safety; N-halamine; polymeric films; renewable
LanguageEnglish
PublisherWiley
JournalMacromolecular Bioscience
ISSN1616-5187
Electronic1616-5195
Publication dates
Online28 Sep 2016
Print16 Mar 2017
Publication process dates
Deposited25 Nov 2019
Submitted21 Jul 2016
Accepted28 Aug 2016
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.1002/mabi.201600304
Scopus EID2-s2.0-84989223273
Web of Science identifierWOS:000397503200014
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