Phenotypic plasticity in melanoma: the impact on management strategies

Magazine

Elayat, G. 2024. Phenotypic plasticity in melanoma: the impact on management strategies. Redactive Publishing.
TypeMagazine
TitlePhenotypic plasticity in melanoma: the impact on management strategies
AuthorsElayat, G.
Abstract

The concept of phenotypic plasticity has emerged as a significant aspect of cancer biology. Phenotypic plasticity, which refers to the ability of organisms or cells to modify their traits in response to different surroundings, is a widespread phenomenon in nature. This adaptability allows organisms to thrive in varying environments. In the context of cancer, phenotypic plasticity plays a crucial role in gene regulatory networks. Cancer cells employ similar mechanisms to adapt and survive within their dynamic microenvironment, especially during processes like metastasis and exposure to therapeutic treatments.

Sustainable Development Goals4 Quality education
Middlesex University ThemeHealth & Wellbeing
Publication or CollectionBiomedical Scientist
ISSN1352-7673
PublisherRedactive Publishing
Institute of Biomedical Science
Publication dates
Online04 Jul 2024
Publication process dates
Deposited14 Aug 2024
Output statusPublished
Web address (URL)https://thebiomedicalscientist.net/2024/07/04/phenotypic-plasticity-melanoma-impact-management-strategies
Permalink -

https://repository.mdx.ac.uk/item/17x291

Log in to edit
  • 13
    total views
  • 0
    total downloads
  • 2
    views this month
  • 0
    downloads this month

Export as

Related outputs

Angiogenesis in breast cancer: insights and innovations
Elayat, G. and Selim, A. 2024. Angiogenesis in breast cancer: insights and innovations. Clinical and Experimental Medicine. 24 (1). https://doi.org/10.1007/s10238-024-01446-5
Positive correlational shift between crevicular antimicrobial peptide LL-37, pain and periodontal status following non-surgical periodontal therapy. A pilot study
Madruga, D., Garcia, M., Martino, L., Hassan, H., Elayat, G., Ghali, L. and Ceballos, L. 2023. Positive correlational shift between crevicular antimicrobial peptide LL-37, pain and periodontal status following non-surgical periodontal therapy. A pilot study. BMC Oral Health. 23 (1), p. 335. https://doi.org/10.1186/s12903-023-03023-w
An overview of angiogenesis in bladder cancer
Elayat, G., Punev, I. and Selim, A. 2023. An overview of angiogenesis in bladder cancer. Current Oncology Reports. 25 (7), pp. 709-728. https://doi.org/10.1007/s11912-023-01421-5
Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment
Owen, H., Appiah, S., Hasan, N., Ghali, L., Elayat, G. and Bell, C. 2017. Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment. in: Zeng, B. and Zhao, K. (ed.) Neurobiology of Chinese Herb Medicine Elsevier.
Cyclin D-1 protein over-expression is not associated with gene amplification in benign and atypical apocrine lesions of the breast
Elayat, Ghada, Selim, Abdel-Ghani A., Gorman, Patricia, Tomlinson, Ian and Wells, Clive A. 2011. Cyclin D-1 protein over-expression is not associated with gene amplification in benign and atypical apocrine lesions of the breast. Pathology - Research and Practice. 207 (2), pp. 75-78. https://doi.org/10.1016/j.prp.2010.06.003
Cell turnover in apocrine metaplasia and apocrine adenosis of the breast
Elayat, G., Selim, A. and Wells, C. 2010. Cell turnover in apocrine metaplasia and apocrine adenosis of the breast. Annals of Diagnostic Pathology. 14 (1), pp. 1-7. https://doi.org/10.1016/j.anndiagpath.2009.05.001
Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast
Elayat, G., Selim, A. and Wells, C. 2009. Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast. Breast Journal. 15 (5), pp. 475-482. https://doi.org/10.1111/j.1524-4741.2009.00762.x
Cell cycle alterations and their relationship to proliferation in apocrine adenosis of the breast
Elayat, G., Selim, A. and Wells, C. 2009. Cell cycle alterations and their relationship to proliferation in apocrine adenosis of the breast. Histopathology. 54 (3), pp. 348-354. https://doi.org/10.1111/j.1365-2559.2009.03223.x
Non-operative breast pathology: Apocrine lesions
Wells, C. and Elayat, G. 2007. Non-operative breast pathology: Apocrine lesions. Journal of Clinical Pathology. 60 (12), pp. 1313-1320. https://doi.org/10.1136/jcp.2006.040626
C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast
Selim, A., Elayat, G., Naase, M. and Wells, C. 2002. C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast. The Breast. 11 (6), pp. 466-472. https://doi.org/10.1054/brst.2002.0474
Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast
Selim, A., Elayat, G. and Wells, C. 2002. Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast. Virchows Archiv. 441, p. 449–455. https://doi.org/10.1007/s00428-002-0691-0
Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: Microdissection microsatellite analysis
Selim, A., Ryan, A., Elayat, G. and Wells, C. 2002. Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: Microdissection microsatellite analysis. The Journal of Pathology. 196 (3), pp. 287-291. https://doi.org/10.1002/path.1043
c-erbB2 oncoprotein expression, gene amplification, and chromosome 17 aneusomy in apocrine adenosis of the breast
Selim, A., Elayat, G. and Wells, C. 2000. c-erbB2 oncoprotein expression, gene amplification, and chromosome 17 aneusomy in apocrine adenosis of the breast. The Journal of Pathology. 191 (2), pp. 138-142. https://doi.org/10.1002/(sici)1096-9896(200006)191:2<138::aid-path611>3.0.co;2-j