Dr Ghada Elayat


Dr Ghada Elayat
NameDr Ghada Elayat
Job titleLecturer in Medical Sciences
Research institute
Primary appointmentNatural Sciences
Email addressg.elayat@mdx.ac.uk
ORCIDhttps://orcid.org/0000-0002-8198-4309
Contact categoryResearcher

Biography

Biography

Dr Ghada Elayat

MBChB, PhD, CSci, FIBMS, FHEA

My journey in medicine began in Egypt, where I initially trained as a histopathologist. Later, I continued my training at the Histopathology Department, St Bartholomew's Hospital. While pursuing my PhD at the University of London, I also registered with the General Medical Council for a period to continue my training in Histopathology. After completing my PhD in 2006, I decided to shift my career towards academia and continued my career as a histopathologist and lecturer. In 2013, I joined MDX as a lecturer specialising in histopathology and clinical sciences. In 2022, I took on the role of Programme Leader for the BSc Medical Science programme, which has been running for two years now, with our first cohort set to graduate in 2025.

My PhD studies were focused on breast cancer biology with special interest in apocrine metaplastic changes and their relation to cancer development. My work in this area has resulted  in several publications in peer-reviewed journals. As my research evolved, I shifted my focus to bladder cancers, with a particular emphasis on the complexities of the tumour microenvironment.  In addition, I have explored the domains of chronic inflammation and actively contributed to research involving the antimicrobial peptides  pain, and periodontal status. My collective research work in the past six years has resulted in further publications in peer-reviewed journals, highlighting the continuous contributions to the advancement of knowledge in the field of cancer biology.

As a Fellow of the Institute of Biomedical Science (FIBMS) and a Chartered Scientist, I am deeply committed to upholding the highest professional standards in my field. Serving as an IBMS mentor, I am dedicated to nurturing the growth and development of fellow scientists, fostering a culture of excellence in both research and practice. 

Teaching

Programme leader BSc Medical Science

Module leader: BMS2125, BMS2515, BMS3326

I teach at both undergraduate/ postgraduate level and across several programmes.

Modules taught at undergraduate level:  BMS1014, BMS2125, BMS2515, BMS3136, BMS3326 and BMS3336 and BIO3419.

Modules taught at postgraduate level: BMS4217, BMS4237, BMS4507, BMS4547, BMS4227, BMS4117, BMS4137, BMS4997 and BMS4147

Supervisor of MSc, MRes and PhD projects.

Employment

Lecturer & Programme Leader BSc Medical Science
MDX
06 Jan 2020
31 Aug 2024

Education and qualifications

MBChB, Honours,
01 May 1993
Tanta University, Faculty of Medicine, Egypt
MSc
01 Feb 1997
Tanta University, Faculty of Medicine, Egypt
Doctorate in Molecular Pathology
01 May 2006
University of London, Queen Mary and Westfield College
Post Graduate Certificate in Higher Education
01 Jan 2018
Middlesex University

Grants

Joint Clinical Research Board (JCRB), Barts health NHS trust and Queen Mary University of London, UK, 2001
01 Jan 2001
Joint Clinical Research Board (JCRB), Barts health NHS trust and Queen Mary University of London, UK
Egyptian Government
01 Jan 1999
Egyptian Government, Higher Education Department

Prizes and Awards

Research outputs

Positive correlational shift between crevicular antimicrobial peptide LL-37, pain and periodontal status following non-surgical periodontal therapy. A pilot study

Madruga, D., Garcia, M., Martino, L., Hassan, H., Elayat, G., Ghali, L. and Ceballos, L. 2023. Positive correlational shift between crevicular antimicrobial peptide LL-37, pain and periodontal status following non-surgical periodontal therapy. A pilot study. BMC Oral Health. 23 (1), p. 335. https://doi.org/10.1186/s12903-023-03023-w

An overview of angiogenesis in bladder cancer

Elayat, G., Punev, I. and Selim, A. 2023. An overview of angiogenesis in bladder cancer. Current Oncology Reports. 25 (7), pp. 709-728. https://doi.org/10.1007/s11912-023-01421-5

Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment

Owen, H., Appiah, S., Hasan, N., Ghali, L., Elayat, G. and Bell, C. 2017. Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment. in: Zeng, B. and Zhao, K. (ed.) Neurobiology of Chinese Herb Medicine Elsevier.

Cyclin D-1 protein over-expression is not associated with gene amplification in benign and atypical apocrine lesions of the breast

Elayat, Ghada, Selim, Abdel-Ghani A., Gorman, Patricia, Tomlinson, Ian and Wells, Clive A. 2011. Cyclin D-1 protein over-expression is not associated with gene amplification in benign and atypical apocrine lesions of the breast. Pathology - Research and Practice. 207 (2), pp. 75-78. https://doi.org/10.1016/j.prp.2010.06.003

Cell turnover in apocrine metaplasia and apocrine adenosis of the breast

Elayat, G., Selim, A. and Wells, C. 2010. Cell turnover in apocrine metaplasia and apocrine adenosis of the breast. Annals of Diagnostic Pathology. 14 (1), pp. 1-7. https://doi.org/10.1016/j.anndiagpath.2009.05.001

Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast

Elayat, G., Selim, A. and Wells, C. 2009. Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast. Breast Journal. 15 (5), pp. 475-482. https://doi.org/10.1111/j.1524-4741.2009.00762.x

Cell cycle alterations and their relationship to proliferation in apocrine adenosis of the breast

Elayat, G., Selim, A. and Wells, C. 2009. Cell cycle alterations and their relationship to proliferation in apocrine adenosis of the breast. Histopathology. 54 (3), pp. 348-354. https://doi.org/10.1111/j.1365-2559.2009.03223.x

Non-operative breast pathology: Apocrine lesions

Wells, C. and Elayat, G. 2007. Non-operative breast pathology: Apocrine lesions. Journal of Clinical Pathology. 60 (12), pp. 1313-1320. https://doi.org/10.1136/jcp.2006.040626

C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast

Selim, A., Elayat, G., Naase, M. and Wells, C. 2002. C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast. The Breast. 11 (6), pp. 466-472. https://doi.org/10.1054/brst.2002.0474

Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast

Selim, A., Elayat, G. and Wells, C. 2002. Expression of c-erbB2, p53, Bcl-2, Bax, c-myc and Ki-67 in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast. Virchows Archiv. 441, p. 449–455. https://doi.org/10.1007/s00428-002-0691-0

Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: Microdissection microsatellite analysis

Selim, A., Ryan, A., Elayat, G. and Wells, C. 2002. Loss of heterozygosity and allelic imbalance in apocrine metaplasia of the breast: Microdissection microsatellite analysis. The Journal of Pathology. 196 (3), pp. 287-291. https://doi.org/10.1002/path.1043

c-erbB2 oncoprotein expression, gene amplification, and chromosome 17 aneusomy in apocrine adenosis of the breast

Selim, A., Elayat, G. and Wells, C. 2000. c-erbB2 oncoprotein expression, gene amplification, and chromosome 17 aneusomy in apocrine adenosis of the breast. The Journal of Pathology. 191 (2), pp. 138-142. https://doi.org/10.1002/(sici)1096-9896(200006)191:2<138::aid-path611>3.0.co;2-j
  • 479
    total views of outputs
  • 8
    total downloads of outputs
  • 18
    views of outputs this month
  • 2
    downloads of outputs this month