C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast
Article
Selim, A., Elayat, G., Naase, M. and Wells, C. 2002. C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast. The Breast. 11 (6), pp. 466-472. https://doi.org/10.1054/brst.2002.0474
Type | Article |
---|---|
Title | C-myc oncoprotein expression and gene amplification in apocrine metaplasia and apocrine change within sclerosing adenosis of the breast |
Authors | Selim, A., Elayat, G., Naase, M. and Wells, C. |
Abstract | Overexpression and/or amplification of c- myc oncogene are known to occur in human breast carcinomas, particularly those of high grade. Apocrine metaplasia (APM) is a common finding within fibrocystic change, and in some cases appears to be associated with an elevated risk of subsequent breast cancer. It has been suggested that apocrine metaplasia within sclerosing adenosis of the breast, also called apocrine adenosis (AA), has a premalignant potential. Little, however, is known about cellular level genetic alterations in either APM or AA of the breast. Because of this, c- myc expression and amplification in APM and AA were studied. |
Publisher | Elsevier |
Churchill Livingstone | |
Journal | The Breast |
ISSN | 0960-9776 |
Publication dates | |
Dec 2002 | |
Publication process dates | |
Deposited | 22 Jun 2009 |
Output status | Published |
Additional information | PubMed PMID: 14965711. |
Digital Object Identifier (DOI) | https://doi.org/10.1054/brst.2002.0474 |
Language | English |
https://repository.mdx.ac.uk/item/81v1w
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