Do electrical stimulation enhance pressure ulcer healing in people living with spinal cord injuries: a meta-analysis and systematic review of randomised and non-randomised controlled trials

Conference paper

Liu, L., Moody, J. and Gall, A. 2015. Do electrical stimulation enhance pressure ulcer healing in people living with spinal cord injuries: a meta-analysis and systematic review of randomised and non-randomised controlled trials. 25th Conference of the European Wound Management Association (EWMA 2015). ExCeL London, UK 13 - 15 May 2015
TypeConference paper
TitleDo electrical stimulation enhance pressure ulcer healing in people living with spinal cord injuries: a meta-analysis and systematic review of randomised and non-randomised controlled trials
AuthorsLiu, L., Moody, J. and Gall, A.
Abstract

Aim: To quantitatively analyse the effect of ES on PrU healing compared with standard wound care (SWC) and/or sham stimulation.
Method: Review was limited to peer-reviewed studies published in English from 1970 to May 2014. Studies included randomized controlled trials (RCTs) and non-RCTs. Methodological quality was assessed using established instruments. Pooled analyses were performed to calculate mean difference (MD) for continuous data, odds ratio (OR) for dichotomous data.
Results / Discussion: Eight prospective controlled studies were reviewed, five studies were RCTs, and three studies were non-RCTs. Pooled analyses of eight trials showed ES significantly improved daily healing rate (MD 0.89, 95% CI 0.23-1.55, p=0.008) with significant heterogeneity. Pulsed current ES significantly improved daily healing rates compared with constant direct current (DC) or alternating current (AC) in two trials (MD 1.50, 95% CI 0.62, 2.39, p=0.0009, I2=81%). Pooled analysis of two trials showed significant higher numbers of ulcer healed (OR 2.95, 95% CI 1.69–5.17, p=0.0002, I2=0%) with ES treatment. There was a trend towards less number of ulcer worsened with ES treatment (OR 0.38, 95% CI 0.12–1.24, p=0.11, I2=18%).intervals (CI).
Conclusion: ES can significantly enhance PrU healing in SCI according to limited level I evidence. Pulsed current ES may confer better benefit on PrU healing than DC or AC. Electrodes placed on wound bed maybe superior to those applied on the intact skin.

Conference25th Conference of the European Wound Management Association (EWMA 2015)
Publication dates
Print14 May 2015
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Deposited22 Apr 2015
Output statusPublished
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Attached is an author version of a conference paper presented at the 25th Conference of the European Wound Management Association (EWMA 2015).

Web address (URL)http://ewma2015.org/scientific/ewma-2015-abstracts.html
LanguageEnglish
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