Dr Sandra Appiah


NameDr Sandra Appiah
Job titleAssociate Professor in Chemistry/Biochemistry
Research institute
Primary appointmentNatural Sciences
Email addresss.appiah@mdx.ac.uk
ORCIDhttps://orcid.org/0000-0002-7497-3388
Contact categoryResearcher

Research outputs

Intentionality for inclusivity - the journey at Middlesex University

Roberts, H., Punev, I., Allardyce, D., Kyprianou, A., Appiah, S., Megeney, A., Calin, A., Gallacher, D. and Mill, R. 2022. Intentionality for inclusivity - the journey at Middlesex University. McGraw Hill.

Betulinic Acid–Doxorubicin-Drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model

Vu, M., Kassouf, N. and Appiah, S. 2021. Betulinic Acid–Doxorubicin-Drug combination induced apoptotic death via ROS stimulation in a relapsed AML MOLM-13 cell model. Antioxidants. 10 (9). https://doi.org/10.3390/antiox10091456

α-Mangostin and Doxorubicin Combination Synergistically Inhibited Cell Growth, Induced Cell Apoptosis with Increased Bak Protein and Decreased FLT3-ITD Phosphorylation in AML MOLM-13 Cell Line

Osemeke, C., Wen, S., Garelick, H. and Appiah, S. 2021. α-Mangostin and Doxorubicin Combination Synergistically Inhibited Cell Growth, Induced Cell Apoptosis with Increased Bak Protein and Decreased FLT3-ITD Phosphorylation in AML MOLM-13 Cell Line. Clinical Oncology and Research. 4 (8), pp. 1-10. https://doi.org/10.31487/j.COR.2021.08.12

Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 expression

Vu, M., Kassouf, N., Ofili, R., Lund, T., Bell, C. and Appiah, S. 2020. Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl‑2 in acute myeloid leukaemia MOLM‑13 cells with reduced Beclin 1 expression. International Journal of Oncology. 57 (1), pp. 113-121. https://doi.org/10.3892/ijo.2020.5052

Betulinic acid-doxorubicin drug combination synergistically supresses cell viability and enhances apoptotic death in acute myeloid leukaemia cell lines by increasing Bax/Bcl-2 ratio

Vu, M., Kassouf, N., Bell, C. and Appiah, S. 2018. Betulinic acid-doxorubicin drug combination synergistically supresses cell viability and enhances apoptotic death in acute myeloid leukaemia cell lines by increasing Bax/Bcl-2 ratio. NCRI Cancer Conference (2018). Glasgow, Scotland 04 - 06 Nov 2018

The combination of curcumin and doxorubicin shows a selective cytotoxic effect on acute myeloid leukaemia cell line

Hasan, N., Roberts, H., Ghali, L. and Appiah, S. 2018. The combination of curcumin and doxorubicin shows a selective cytotoxic effect on acute myeloid leukaemia cell line. NCRI Cancer Conference (2018). Glasgow, Scotland 04 - 06 Nov 2018

α-Mangostin, singly and in combination with Doxorubicin, as pro-apoptotic agents and protein kinase inhibitors In the AML cell line, Molm13

Osemeke, C., Garelick, H., Wen, S. and Appiah, S. 2018. α-Mangostin, singly and in combination with Doxorubicin, as pro-apoptotic agents and protein kinase inhibitors In the AML cell line, Molm13. EACR Conference Series: A matter of Life or Death. from Basic cell Death Mechanism to Novel cancer Treatment. Amstardam, Netherlands

Liposome‑delivered baicalein induction of myeloid leukemia K562 cell death via reactive oxygen species generation

Wang, S., Wen, S., Bell, C. and Appiah, S. 2018. Liposome‑delivered baicalein induction of myeloid leukemia K562 cell death via reactive oxygen species generation. Molecular Medicine Reports. 17 (3), pp. 4524-4530. https://doi.org/10.3892/mmr.2018.8396

Doxorubicin combined with Alpha Mangostin as pro-apoptotic agents and as potential kinase inhibitors of acute Myeloid Leukaemia

Osemeke, C., Garelick, H., Wen, S. and Appiah, S. 2017. Doxorubicin combined with Alpha Mangostin as pro-apoptotic agents and as potential kinase inhibitors of acute Myeloid Leukaemia. 2017 NCRI Cancer Conference. Liverpool, UK 05 - 08 Nov 2017

Evidence for the outcomes and impact of clinical pharmacy: context of UK hospital pharmacy practice

Onatade, R., Appiah, S., Stephens, M. and Garelick, H. 2018. Evidence for the outcomes and impact of clinical pharmacy: context of UK hospital pharmacy practice. European Journal of Hospital Pharmacy. 25 (e1), pp. e21-e28. https://doi.org/10.1136/ejhpharm-2017-001303

Potential interactions of Alpha Mangostin with Doxorubicin as potential Kinase inhibitors on myeloid leukaemic cell line

Osemeke, C., Garelick, H., Wen, S. and Appiah, S. 2017. Potential interactions of Alpha Mangostin with Doxorubicin as potential Kinase inhibitors on myeloid leukaemic cell line. 2017 Middlesex University Research Student Summer Conference. London, UK 28 - 29 Jun 2017

Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study

Appiah, S., Lawley, B., Vu, M., Bell, C. and Jones, H. 2017. Evaluation of the effectiveness of Eladi Keram for the treatment of acne vulgaris: a randomised controlled pilot study. European Journal of Integrative Medicine. 12, pp. 38-43. https://doi.org/10.1016/j.eujim.2017.04.004

Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment

Owen, H., Appiah, S., Hasan, N., Ghali, L., Elayat, G. and Bell, C. 2017. Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment. in: Zeng, B. and Zhao, K. (ed.) Neurobiology of Chinese Herb Medicine Elsevier.

Antiinflammatory and hepatoprotective medicinal herbs as potential substitutes for bear bile

Appiah, S., Revitt, D., Jones, H., Vu, M., Simmonds, M. and Bell, C. 2017. Antiinflammatory and hepatoprotective medicinal herbs as potential substitutes for bear bile. in: Zeng, B. and Zhao, K. (ed.) Neurobiology of Chinese Herb Medicine Elsevier.

Combinational effect of phytochemicals on the action of chemotherapy drugs on acute myeloid leukaemic cell lines

Osemeke, C., Garelick, H., Wen, S. and Appiah, S. 2016. Combinational effect of phytochemicals on the action of chemotherapy drugs on acute myeloid leukaemic cell lines. 2016 Middlesex University Research Student Summer Conference. London, UK 29 - 30 Jun 2016

Potential interaction between natural compounds and chemotherapeutic drugs on leukaemia cell line

Osemeke, C., Garelick, H., Wen, S. and Appiah, S. 2015. Potential interaction between natural compounds and chemotherapeutic drugs on leukaemia cell line. 2015 Middlesex University Research Student Summer Conference. Middlesex University, London, United Kingdom 17 - 18 Jun 2015

The role of vitamin In type 2 diabetes

Ali, A., Appiah, S., Shah, A. and Ghali, L. 2014. The role of vitamin In type 2 diabetes. Middlesex University Postgraduate Summer Conference. London, UK 19 Jun 2014

Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines

Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2014. Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines. Middlesex University Postgraduate Summer Conference. London, UK 19 Jun 2014

Impact of inulin on bile acids induced colon cancer

Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2013. Impact of inulin on bile acids induced colon cancer. Third AACR International Conference on Frontiers in Basic Cancer Research. National Harbor, MD, United States 18 - 22 Sep 2013

Evaluation of herbs as potential alternatives for bear bile and rhino horn used in traditional Chinese medicines: chemical and biological analysis.

Appiah, S. 2006. Evaluation of herbs as potential alternatives for bear bile and rhino horn used in traditional Chinese medicines: chemical and biological analysis. PhD thesis Middlesex University School of Health and Social Sciences

Screening for Downs Syndrome pregnancy by mass spectral glycofingerprinting hCG-beta core in neat pregnancy urine.

Luttoo, J., Appiah, S., Butler, S. and Iles, R. 2009. Screening for Downs Syndrome pregnancy by mass spectral glycofingerprinting hCG-beta core in neat pregnancy urine. Middlesex University Postgraduate Summer Conference. London, UK

Herbal alternatives to bear bile: effects of scutellaria baicalensis Georgi on IL-6 promoter and CYP3A4 activities.

Appiah, S., Bremner, P., Kokubun, T., Russell, M., Bell, C., Heinrich, M. and Simmonds, M. 2006. Herbal alternatives to bear bile: effects of scutellaria baicalensis Georgi on IL-6 promoter and CYP3A4 activities. 13th Annual Symposium on Complementary Health Care. Exeter, UK 12 - 14 Dec 2006

Plant substances as alternatives for animal products in traditional medicines.

Bell, C., Simmonds, M., Appiah, S. and Howes, M. 2006. Plant substances as alternatives for animal products in traditional medicines. London Department for the Environment, Food and Rural Affairs.

Investigation of the safety and efficacy of Chinese herbs traditionally used to treat inflammatory diseases

Appiah, S., Kokubun, T., Bremner, P., Heinrich, M., Bell, C. and Simmonds, M. 2003. Investigation of the safety and efficacy of Chinese herbs traditionally used to treat inflammatory diseases. 10th Annual Symposium on Complementary Health Care. London, UK 21 - 22 Nov 2003
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