Screen key genes associated with distraction-induced osteogenesis of stem cells using bioinformatics methods
Article
Chen, J., Hua, J. and Song, W. 2021. Screen key genes associated with distraction-induced osteogenesis of stem cells using bioinformatics methods. International Journal of Molecular Sciences. 22 (12). https://doi.org/10.3390/ijms22126505
Type | Article |
---|---|
Title | Screen key genes associated with distraction-induced osteogenesis of stem cells using bioinformatics methods |
Authors | Chen, J., Hua, J. and Song, W. |
Abstract | Background: Applying mesenchymal stem cells (MSCs), together with the distraction osteogenesis (DO) process, displayed enhanced bone quality and shorter treatment periods. The DO guides the differentiation of MSCs by providing mechanical clues. However, the underlying key genes and pathways are largely unknown. The aim of this study was to screen and identify hub genes involved in distraction-induced osteogenesis of MSCs and potential molecular mechanisms. |
Keywords | Bioinformatics, distraction osteogenesis, gene expression, microarray, mesenchymal stem cells |
Research Group | Biophysics and Bioengineering group |
Publisher | MDPI AG |
Journal | International Journal of Molecular Sciences |
ISSN | 1661-6596 |
Electronic | 1422-0067 |
Publication dates | |
Online | 17 Jun 2021 |
17 Jun 2021 | |
Publication process dates | |
Deposited | 21 Jun 2021 |
Accepted | 14 Jun 2021 |
Output status | Published |
Publisher's version | License File Access Level Open |
Copyright Statement | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Additional information | This article belongs to the Special Issue Different Strategies for Osteogenic Differentiation and Bone Regeneration. |
Digital Object Identifier (DOI) | https://doi.org/10.3390/ijms22126505 |
Language | English |
https://repository.mdx.ac.uk/item/8965x
Download files
51
total views8
total downloads2
views this month0
downloads this month