Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3

Article


Nicolaou, K., Frederick, M., Petrovic, G., Cole, K. and Loizidou, E. 2006. Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. Angewandte Chemie International Edition. 45 (16), pp. 2609-2615. https://doi.org/10.1002/anie.200600295
TypeArticle
TitleTotal synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3
AuthorsNicolaou, K., Frederick, M., Petrovic, G., Cole, K. and Loizidou, E.
Abstract

The 39 steps: The recently proposed revised structures of azaspiracid-2 and -3 (see picture), the two most potent members of the azaspiracid family, have been confirmed through the total syntheses of the two compounds. These 39-step syntheses represent a major improvement over the first-generation synthesis of azaspiracid-1 (50 steps).

PublisherWiley-VCH Verlag
JournalAngewandte Chemie International Edition
ISSN1433-7851
Publication dates
Print10 Apr 2006
Publication process dates
Deposited06 Mar 2015
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.1002/anie.200600295
LanguageEnglish
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