Dr Erika Loizidou


NameDr Erika Loizidou
Job titleHourly Academic
Research institute
Primary appointmentNatural Sciences
ORCIDhttps://orcid.org/0000-0002-4834-6639
Contact categoryAcademic staff (past)

Research outputs

Identification of a new class of proteasome inhibitors based on a naphthyl-azotricyclic-urea-phenyl scaffold

Allardyce, D., Adu Mantey, P., Szalecka, M., Nkwo, R. and Loizidou, E. 2023. Identification of a new class of proteasome inhibitors based on a naphthyl-azotricyclic-urea-phenyl scaffold. RSC Medicinal Chemistry. 14 (3), pp. 573-582. https://doi.org/10.1039/D2MD00404F

Nanomedicines and microneedles: A guide to their analysis and application

Sully, R., Moore, C., Garelick, H., Loizidou, E., Podoleanu, A. and Gubala, V. 2021. Nanomedicines and microneedles: A guide to their analysis and application. Analytical Methods. 13 (30), pp. 3326-3347. https://doi.org/10.1039/d1ay00954k

Nanoparticle-infused-biodegradable-microneedles as drug-delivery systems: Preparation and characterisation

Sully, R., Garelick, H., Loizidou, E., Podoleanu, A. and Gubala, V. 2021. Nanoparticle-infused-biodegradable-microneedles as drug-delivery systems: Preparation and characterisation. Materials Advances. 2 (16), pp. 5432-5442. https://doi.org/10.1039/D1MA00135C

An experimental FTIR-ATR and computational study of H-bonding in ethanol/water mixtures

Zeinalipour-Yazdi, C. and Loizidou, E. 2021. An experimental FTIR-ATR and computational study of H-bonding in ethanol/water mixtures. Chemical Physics. 550 (1), pp. 1-7. https://doi.org/10.1016/j.chemphys.2021.111295

Size-dependent bond dissociation enthalpies in single-walled carbon nanotubes

Zenalipour-Yazdi, C., Loizidou, E. and Chutia, A. 2019. Size-dependent bond dissociation enthalpies in single-walled carbon nanotubes. Chemical Physics Letters. 731, pp. 1-6. https://doi.org/10.1016/j.cplett.2019.136628

Argyrin B a non-competitive inhibitor of the human immunoproteasome exhibiting preference for β1i

Allardyce, D., Bell, C. and Loizidou, E. 2019. Argyrin B a non-competitive inhibitor of the human immunoproteasome exhibiting preference for β1i. Chemical Biology and Drug Design. 94 (2), pp. 1556-1567. https://doi.org/10.1111/cbdd.13539

The potential use of microneedles as an alternative method for skin cancer treatment

Loizidou, E., Yagnik, D., Szalecka, M. and Nguyen, D. 2019. The potential use of microneedles as an alternative method for skin cancer treatment. The World Congress on Advanced Treatments and Technologies in Skin Cancer (Skin-Cancer2019). Vienna, Austria 04 - 05 Apr 2019

Analysis of argyrin B binding at constitutive and immunoproteasome active sites using molecular modelling and kinetic assays

Allardyce, D., Bell, C. and Loizidou, E. 2017. Analysis of argyrin B binding at constitutive and immunoproteasome active sites using molecular modelling and kinetic assays. Computational Advances in Drug Discovery (Structure Based Drug Design). Lausanne, Switzerland 05 - 08 Sep 2017

Study of the cap structure of (3,3), (4,4) and (5,5)-SWCNTs: application of the sphere-in-contact model

Zeinalipour-Yazdi, C. and Loizidou, E. 2017. Study of the cap structure of (3,3), (4,4) and (5,5)-SWCNTs: application of the sphere-in-contact model. Carbon. 115, pp. 819-827. https://doi.org/10.1016/j.carbon.2017.01.074

Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis

Loizidou, E., Inoue, N., Ashton-Barnett, J., Barrow, D. and Allender, C. 2016. Evaluation of geometrical effects of microneedles on skin penetration by CT scan and finite element analysis. European Journal of Pharmaceutics and Biopharmaceutics. 107, pp. 1-6. https://doi.org/10.1016/j.ejpb.2016.06.023

Teaching atomic structure as a threshold concept in chemistry for biologists

Loizidou, E. and Jones, H. 2016. Teaching atomic structure as a threshold concept in chemistry for biologists. 253rd American Chemical Society National Meeting & Exposition. San Francisco, CA, USA 02 - 06 Apr 2017

Part I: total synthesis of azaspiracid-3 Part II: molecular recognition studies in aqueous solutions facilitated by a receptor-modified polymer

Loizidou, E. 2006. Part I: total synthesis of azaspiracid-3 Part II: molecular recognition studies in aqueous solutions facilitated by a receptor-modified polymer. PhD thesis University of California San Diego / San Diego State University Chemistry

Structural characterization and transdermal delivery studies on sugar microneedles: experimental and finite element modelling analyses

Loizidou, E., Williams, N., Barrow, D., Eaton, M., McCrory, J., Evans, S. and Allender, C. 2015. Structural characterization and transdermal delivery studies on sugar microneedles: experimental and finite element modelling analyses. European Journal of Pharmaceutics and Biopharmaceutics. 89, pp. 224-231. https://doi.org/10.1016/j.ejpb.2014.11.023

Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity

Loizidou, E. and Zeinalipour-Yazdi, C. 2014. Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity. Chemical Biology and Drug Design. 84 (1), pp. 99-107. https://doi.org/10.1111/cbdd.12298

Design of argyrin analogues as proteasome inhibitors with subunit specicificity

Loizidou, E. and Zeinalipour-Yazdi, C. 2014. Design of argyrin analogues as proteasome inhibitors with subunit specicificity. 247th ACS National Meeting. Dallas, TX, USA 16 - 20 Mar 2014

Simulating the effect of geometry on the structural properties of microneedles

Loizidou, E., Ashton-Barnett, J., Barrow, D. and Allender, C. 2014. Simulating the effect of geometry on the structural properties of microneedles. Perspectives in Percutaneous Penetration Fourteenth International Conference including FP7 HIPODERM Symposium on High Potency Dermatologicals. La Grande Motte, France 23 - 25 Apr 2014

Structural properties of sugar microneedles: a finite element analysis

Loizidou, E., Barrow, D. and Allender, C. 2014. Structural properties of sugar microneedles: a finite element analysis. Perspectives in Percutaneous Penetration Fourteenth International Conference including FP7 HIPODERM Symposium on High Potency Dermatologicals. La Grande Motte, France 23 - 25 Apr 2014

Rational design of argyrin analogues as selective inhibitors of the proteasome

Loizidou, E. and Zeinalipour-Yazdi, C. 2012. Rational design of argyrin analogues as selective inhibitors of the proteasome. COST Conference on Personalised Medicine. Larnaca, Cyprus 17 - 22 Jun 2012

Multi-objective optimization methods in de novo drug design

Nicolaou, C., Kannas, C. and Loizidou, E. 2012. Multi-objective optimization methods in de novo drug design. Mini Reviews in Medicinal Chemistry. 12 (10), pp. 979-987. https://doi.org/10.2174/138955712802762284

Receptor-attached amphiphilic terpolymer for selective drug recognition in aqueous solutions

Loizidou, E., Sun, L. and Zeinalipour-Yazdi, C. 2011. Receptor-attached amphiphilic terpolymer for selective drug recognition in aqueous solutions. Journal of Molecular Recognition. 24 (4), pp. 678-686. https://doi.org/10.1002/jmr.1098

Analysis of binding parameters of HIV-1 integrase inhibitors: correlates of drug inhibition and resistance

Loizidou, E., Zeinalipour-Yazdi, C., Christofides, T. and Kostrikis, L. 2009. Analysis of binding parameters of HIV-1 integrase inhibitors: correlates of drug inhibition and resistance. Bioorganic & Medicinal Chemistry. 17 (13), pp. 4806-4818. https://doi.org/10.1016/j.bmc.2009.04.058

Implications of HIV-1 M group polymorphisms on intergase inhibitor efficacy and resistance: genetic and structural in-silico analyses

Loizidou, E., Kousiappa, I., Zeinalipour-Yazdi, C., Van De Vijver, D. and Kostrikis, L. 2009. Implications of HIV-1 M group polymorphisms on intergase inhibitor efficacy and resistance: genetic and structural in-silico analyses. Biochemistry. 48 (1), pp. 4-6. https://doi.org/10.1021/bi8019349

Structure-based computational analysis of the implications of subtype specific polymorphisms on the efficacy of integrase inhibitors

Loizidou, E., Kousiappa, I., Zeinalipour-Yazdi, C., Van De Vijver, D. and Kostrikis, L. 2009. Structure-based computational analysis of the implications of subtype specific polymorphisms on the efficacy of integrase inhibitors. 7th European HIV Drug Resistance Workshop. Stockholm, Sweden

Structural assignment and total synthesis of azaspiracid-1

Frederick, M., Cole, K., Petrovic, G., Loizidou, E. and Nicolaou, K. 2007. Structural assignment and total synthesis of azaspiracid-1. in: Botana, L. (ed.) Phycotoxins: chemistry and biochemistry Ames, Iowa WileyBlackwell. pp. 297-309

HIV-1 integrase inhibitors: from biology to chemotherapeutics

Loizidou, E., Nicolaou, C., Nicolaides, A. and Kostrikis, L. 2007. HIV-1 integrase inhibitors: from biology to chemotherapeutics. Current HIV Research. 5 (4), pp. 365-388. https://doi.org/10.2174/157016207781023965

Second generation total synthesis of azaspiracids-1, -2 and -3

Nicolaou, K., Frederick, M., Loizidou, E., Petrovic, G., Cole, K., Koftis, T. and Yamada, Y. 2006. Second generation total synthesis of azaspiracids-1, -2 and -3. Chemistry: an Asian Journal. 1 (1-2), pp. 245-263. https://doi.org/10.1002/asia.200600059

Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3

Nicolaou, K., Frederick, M., Petrovic, G., Cole, K. and Loizidou, E. 2006. Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3. Angewandte Chemie International Edition. 45 (16), pp. 2609-2615. https://doi.org/10.1002/anie.200600295

Total synthesis and structural elucidation of azaspiracid-1 : construction of key building blocks for originally proposed structure

Nicolaou, K., Pihko, P., Bernal, F., Frederick, M., Qian, W., Uesaka, N., Diedrichs, N., Hinrichs, J., Koftis, T., Loizidou, E., Petrovic, G., Rodriquez, M., Sarlah, D. and Zou, N. 2006. Total synthesis and structural elucidation of azaspiracid-1 : construction of key building blocks for originally proposed structure. Journal of the American Chemical Society. 128 (7), pp. 2244-2257. https://doi.org/10.1021/ja0547477

Studies toward the synthesis of azadirachtin, part 2 : construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-proximity effects

Nicolaou, K., Sasmal, P., Koftis, T., Converso, A., Loizidou, E., Kaiser, F., Roecker, A., Dellios, C., Sun, X. and Petrovic, G. 2005. Studies toward the synthesis of azadirachtin, part 2 : construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-proximity effects. Angewandte Chemie International Edition. 44 (22), pp. 3447-3452. https://doi.org/10.1002/anie.200500217

Artificial receptor-attached amphiphilic copolymer for barbiturate binding in aqueous media

Loizidou, E., Zeinalipour-Yazdi, C. and Sun, L. 2004. Artificial receptor-attached amphiphilic copolymer for barbiturate binding in aqueous media. Biomacromolecules. 5 (5), pp. 1647-1652. https://doi.org/10.1021/bm0497320

Molecular recognition of barbiturate artificial receptor covalently bound to an amphiphilic copolymer

Loizidou, E. and Sun, L. 2003. Molecular recognition of barbiturate artificial receptor covalently bound to an amphiphilic copolymer. 226th ACS National Meeting. New York, New York, USA 07 - 11 Sep 2003

Molecular recognition of barbiturate artificial receptor covalently bound to an amphiphilic copolymer

Loizidou, E. and Sun, L. 2003. Molecular recognition of barbiturate artificial receptor covalently bound to an amphiphilic copolymer. International Symposium on the Synthesis and Characterization of Macromolecules. Amsterdam, Netherlands 07 - 11 Feb 2003

Characterization of amphiphilic polymers covalently attached with Pirkle-concept chiral selectors for chiral seperations by Merck

Loizidou, E., Zhang, K. and Sun, L. 2002. Characterization of amphiphilic polymers covalently attached with Pirkle-concept chiral selectors for chiral seperations by Merck. 224th ACS National Meeting. 18 Aug 2002

Synthesis and characterization of novel networks with nano-engineered structures: cross-linked star homopolymers

Vamvakaki, M., Hadjiyiannakou, S., Loizidou, E. and Patrickios, C. 2001. Synthesis and characterization of novel networks with nano-engineered structures: cross-linked star homopolymers. Chemistry of Materials. 13 (12), pp. 4738-4744. https://doi.org/10.1021/cm010569e

AB diblock and ABC triblock amphiphilic copolymers containing fluorine

Loizidou, E., Haralambous, D., Vamvakaki, M., Patrickios, C., Krasia, T. and Antonietti, M. 2001. AB diblock and ABC triblock amphiphilic copolymers containing fluorine. 221th ACS National Meeting. San Diego, CA, USA 01 Apr 2001
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