Post-operative pediatric cerebellar mutism syndrome and its association with hypertrophic olivary degeneration
Article
Avula, S., Spiteri, M., Kumar, R., Lewis, E., Harave, S., Windridge, D., Ong, C. and Pizer, B. 2016. Post-operative pediatric cerebellar mutism syndrome and its association with hypertrophic olivary degeneration. Quantitative Imaging in Medicine and Surgery. 6 (5), pp. 535-544. https://doi.org/10.21037/qims.2016.10.11
Type | Article |
---|---|
Title | Post-operative pediatric cerebellar mutism syndrome and its association with hypertrophic olivary degeneration |
Authors | Avula, S., Spiteri, M., Kumar, R., Lewis, E., Harave, S., Windridge, D., Ong, C. and Pizer, B. |
Abstract | Background: The dentato-thalamo-cortical (DTC) pathway is recognized as the anatomical substrate for postoperative pediatric cerebellar mutism (POPCMS), a well-recognized complication affecting up to 31% of children undergoing posterior fossa brain tumour resection. The proximal structures of the DTC pathway also form a segment of the Guillain and Mollaret triangle, a neural network which when disrupted causes hypertrophic olivary degeneration (HOD) of the inferior olivary nucleus (ION). We hypothesize that there is an association between the occurrence of POPCMS and HOD and aim to evaluate this on MR imaging using qualitative and quantitative analysis of the ION in children with and without POPCMS. |
Keywords | Cerebellar mutism syndrome (CMS); hypertrophic olivary degeneration; posterior fossa syndrome (PFS); postoperative pediatric cerebellar mutism syndrome |
Publisher | AME Publishing Company |
Journal | Quantitative Imaging in Medicine and Surgery |
ISSN | 2223-4292 |
Electronic | 2223-4306 |
Publication dates | |
Oct 2016 | |
Publication process dates | |
Deposited | 27 Feb 2018 |
Accepted | 10 Oct 2016 |
Submitted | 17 Sep 2016 |
Output status | Published |
Publisher's version | |
Copyright Statement | © Quantitative Imaging in Medicine and Surgery. All rights reserved. Reproduced here with permission of Quantitative Imaging in Medicine and Surgery |
Digital Object Identifier (DOI) | https://doi.org/10.21037/qims.2016.10.11 |
PubMed ID | 27942473 |
PubMed Central ID | 5130563 |
Web of Science identifier | WOS:000391389300008 |
Language | English |
https://repository.mdx.ac.uk/item/877w9
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