Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness
Article
Metrebian, N., Weaver, T., Pilling, S., Goldsmith, K., Carr, E., Shearer, J., Woolston-Thomas, K., Tas, B., Getty, C., Cooper, C., van der Waal, R., Kelleher, M., Finch, E., Bijral, P., Taylor, D., Scott, J. and Strang, J. 2020. Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness. Contemporary Clinical Trials Communications. 17, pp. 1-8. https://doi.org/10.1016/j.conctc.2019.100506
| Type | Article |
|---|---|
| Title | Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness |
| Authors | Metrebian, N., Weaver, T., Pilling, S., Goldsmith, K., Carr, E., Shearer, J., Woolston-Thomas, K., Tas, B., Getty, C., Cooper, C., van der Waal, R., Kelleher, M., Finch, E., Bijral, P., Taylor, D., Scott, J. and Strang, J. |
| Abstract | The majority of people receiving treatment for their heroin addiction, are prescribed methadone; for which there is an extensive evidence base. When treatment starts, people take their daily dose of methadone under supervision at a community pharmacy. Supervision guarantees methadone is taken as directed by the individual for whom it has been prescribed, helps to ensure individuals take their correct dose every day, and safeguards against diversion and overdose. However, individuals often fail to attend the pharmacy to take their methadone. Each missed dose is of concern. If a patient misses their daily dose of methadone, they will start to experience opiate withdrawal and cravings and are more likely to use heroin. If they miss three days dose, there are concerns that they may lose tolerance to the drug and may be at risk of overdose when the next dose is taken. Hence there is an urgent need to develop effective interventions for medication adherence. Research suggests that incentive-based medication adherence interventions may be very effective, but there are few controlled trials and the provision of incentives requires time and organisational systems which can be challenging in pharmacies. The investigators have developed the technology to deliver incentives by mobile telephone. This cluster randomised trial will test the feasibility of conducting a future trial evaluating the clinical and cost effectiveness of using telephone delivered incentives (praise and modest financial rewards via text messaging) to encourage adherence with supervised consumption of methadone in community pharmacies. Three drug services (each with two or three community pharmacies supervising methadone consumption that will enrol 20 individuals, a total of 60 participants) will be recruited and randomly allocated to deliver either i) telephone delivered incentives, ii) telephone delivered reminders or iii) no telephone system. Acceptability, recruitment, follow-up, and suitable measures of clinical and cost effectiveness will be assessed. Findings from this feasibility study will be assessed against stated progression criteria and used to inform a future confirmatory trial of the clinical and cost effectiveness of telephone delivered incentives to encourage medication adherence. ISRCTN58958179 (retrospectively registered). [Abstract copyright: © 2019 Published by Elsevier Inc.] |
| Keywords | Opiate substitution treatment; Methadone; Supervised consumption; Pharmacies; Contingency management; Medication adherence; Financial incentives; Behavioural reinforcement; Heroin use |
| Publisher | Elsevier |
| Journal | Contemporary Clinical Trials Communications |
| ISSN | |
| Electronic | 2451-8654 |
| Publication dates | |
| Online | 10 Dec 2019 |
| 01 Mar 2020 | |
| Publication process dates | |
| Deposited | 21 Jan 2020 |
| Accepted | 07 Dec 2019 |
| Output status | Published |
| Publisher's version | License |
| Copyright Statement | © 2019 Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. |
| Digital Object Identifier (DOI) | https://doi.org/10.1016/j.conctc.2019.100506 |
| Web of Science identifier | WOS:000546224900014 |
| Language | English |
Permalink -
https://repository.mdx.ac.uk/item/88vwq
Download files
77
total views17
total downloads2
views this month0
downloads this month
Export as
Related outputs
Becoming an Open Dialogue practitioner: a qualitative study of practitioners’ training experiences and transitioning to practice
Anestis, E., Weaver, T., Melia, C., Clarke, K. and Pilling, S. 2024. Becoming an Open Dialogue practitioner: a qualitative study of practitioners’ training experiences and transitioning to practice. Frontiers in Psychology. 15, p. 1432327. https://doi.org/10.3389/fpsyg.2024.1432327The effectiveness of the Offender Personality Disorder Pathway: a propensity score-matched analysis
Vamvakas, G., Jarrett, M., Barrett, B., Campbell, C., Forrester, A., Trebilcock, J., Walker, J., Weaver, T., Khondoker, M. and Moran, P. 2024. The effectiveness of the Offender Personality Disorder Pathway: a propensity score-matched analysis. Psychology, Crime and Law. https://doi.org/10.1080/1068316x.2024.2310532A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone
Getty, C., Weaver, T. and Metrebian, N. 2023. A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone. Drug and Alcohol Review. 42 (3), pp. 641-651. https://doi.org/10.1111/dar.13555
A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone
Getty, C., Weaver, T. and Metrebian, N. 2022. A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone. Drug and Alcohol Review. https://doi.org/10.1111/dar.13555Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: prevalence and service needs in an inner London borough
Weaver, T., Rutter, D., Madden, P., Ward, J., Stimson, G. and Renton, A. 2001. Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: prevalence and service needs in an inner London borough. Social Psychiatry and Psychiatric Epidemiology. 36 (8), pp. 399-406. https://doi.org/10.1007/s001270170030The prevalence and management of co-morbid substance misuse and mental illness: results of a screening survey in substance misuse and mental health treatment populations
Weaver, T., Hickman, M., Rutter, D., Ward, J., Stimson, G. and Renton, A. 2001. The prevalence and management of co-morbid substance misuse and mental illness: results of a screening survey in substance misuse and mental health treatment populations. Drug and Alcohol Review. 20 (4), pp. 407-416. https://doi.org/10.1080/09595230120092724Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis.
Mwebe, H., Volante, M. and Weaver, T. 2020. Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis. British Journal of Mental Health Nursing. 9 (3), pp. 1-14. https://doi.org/10.12968/bjmh.2020.0005Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis
Mwebe, H., Volante, M. and Weaver, T. 2020. Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis. British Journal of Cardiac Nursing. 15 (11), pp. 1-15. https://doi.org/10.12968/bjca.2020.0157Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial.
Pilling, S., Clarke, K., Parker, G., James, K., Landau, S., Weaver, T., Razzaque, R. and Craig, T. 2022. Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial. Contemporary Clinical Trials. 113. https://doi.org/10.1016/j.cct.2021.106664Causes of and alternatives to medication for behaviours that challenge in people with intellectual disabilities: direct care providers' perspectives
Deb, S., Limbu, B., Unwin, G. and Weaver, T. 2022. Causes of and alternatives to medication for behaviours that challenge in people with intellectual disabilities: direct care providers' perspectives. International Journal of Environmental Research and Public Health. 19 (16), pp. 1-14. https://doi.org/10.3390/ijerph19169988Patients' beliefs towards contingency management: Target behaviours, incentives and the remote application of these interventions
Getty, C., Weaver, T., Lynskey, M., Kirby, K., Dallery, J. and Metrebian, N. 2022. Patients' beliefs towards contingency management: Target behaviours, incentives and the remote application of these interventions. Drug and Alcohol Review. 41 (1), pp. 96-105. https://doi.org/10.1111/dar.13314Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial
Metrebian, N., Weaver, T., Goldsmith, K., Pilling, S., Hellier, J., Pickles, A., Shearer, J., Byford, S., Mitcheson, L., Bijral, P., Bogdan, N., Bowden-Jones, O., Day, E., Dunn, J., Glasper, A., Finch, E., Forshall, S., Akhtar, S., Bajaria, J., Bennett, C., Bishop, E., Charles, V., Davey, C., Desai, R., Goodfellow, C., Haque, F., Little, N., McKechnie, H., Mosler, F., Morris, J., Mutz, J., Pauli, R., Poovendran, D., Phillips, E. and Strang, J. 2021. Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial. BMJ Open. 11 (7). https://doi.org/10.1136/bmjopen-2020-046371