Assessment of adverse effects in clinical studies of antipsychotic medication: survey of methods used

Article

Pope, A., Adams, C., Paton, C., Weaver, T. and Barnes, T.R.E. 2010. Assessment of adverse effects in clinical studies of antipsychotic medication: survey of methods used. The British Journal of Psychiatry. 197 (1), pp. 67-72. https://doi.org/10.1192/bjp.bp.109.070961
TypeArticle
TitleAssessment of adverse effects in clinical studies of antipsychotic medication: survey of methods used
AuthorsPope, A., Adams, C., Paton, C., Weaver, T. and Barnes, T.R.E.
Abstract

Background: Clinical studies of antipsychotic medication are a primary source of data on the nature of, and relative liability for, adverse effects, relevant to prescribing decisions in clinical practice.
Aims: To identify how safety and tolerability data were collected and reported in recent clinical studies of antipsychotics.
Method: A survey was conducted of all 167 eligible studies published between 2002 and 2007 on the Cochrane Schizophrenia Group register.
Results: Extrapyramidal side-effects (EPS) and weight gain were most frequently assessed. A minority of reports addressed metabolic abnormalities, aversive subjective experiences and sexual dysfunction. Published rating scales were frequently used to evaluate EPS, but systematic methods were rarely applied to other treatment-emergent problems. The definition of individual adverse effects and the manner of reporting were inconsistent.
Conclusions: The way in which safety and tolerability data are collected and reported in clinical studies does not allow for fair and meaningful comparison of the relative risk profiles of individual antipsychotic drugs.

PublisherCambridge University Press (CUP)
Royal College of Psychiatrists
JournalThe British Journal of Psychiatry
ISSN0007-1250
Electronic1472-1465
Publication dates
PrintJul 2010
Publication process dates
Deposited02 Dec 2019
Accepted20 Apr 2010
Output statusPublished
Additional information

Published online by Cambridge University Press: 02 January 2018

Digital Object Identifier (DOI)https://doi.org/10.1192/bjp.bp.109.070961
PubMed ID20592438
Web of Science identifierWOS:000279596900014
Related Output
Has metadatahttp://europepmc.org/abstract/med/20592438
LanguageEnglish
Permalink -

https://repository.mdx.ac.uk/item/88q12

Log in to edit
  • 132
    total views
  • 0
    total downloads
  • 5
    views this month
  • 0
    downloads this month

Export as

Related outputs

Peer-supported Open Dialogue: a qualitative study of peer practitioners’ experiences and non-peer practitioners’ perspectives on peer involvement
Anestis, E., Weaver, T., Tew, J., Carr, S., Hendy, C., Melia, C., Clarke, K. and Pilling, S. 2025. Peer-supported Open Dialogue: a qualitative study of peer practitioners’ experiences and non-peer practitioners’ perspectives on peer involvement. BJPsych Open. 11 (5). https://doi.org/10.1192/bjo.2025.10833
Mobile telephone contingency management to encourage adherence to supervised medication among individuals most at risk of non-adherence to opioid agonist treatment: a study protocol for a feasibility study (TIES2)
Metrebian, N., Getty, C-A., Carr, E., Weaver, T., Pilling, S., Kelleher, M, Scott, J. and Strang, J. 2025. Mobile telephone contingency management to encourage adherence to supervised medication among individuals most at risk of non-adherence to opioid agonist treatment: a study protocol for a feasibility study (TIES2). Pilot and Feasibility Studies. 11 (1). https://doi.org/10.1186/s40814-025-01614-8
Addiction specialists' perspectives on digital contingency management and its role within UK drug and alcohol services: a qualitative exploration
Getty, C., Metrebian, N., Neale, J., Weaver, T. and Strang, J. 2025. Addiction specialists' perspectives on digital contingency management and its role within UK drug and alcohol services: a qualitative exploration. Drug and Alcohol Review. https://doi.org/10.1111/dar.14046
The effectiveness of the Offender Personality Disorder Pathway: a propensity score-matched analysis
Vamvakas, G., Jarrett, M., Barrett, B., Campbell, C., Forrester, A., Trebilcock, J., Walker, J., Weaver, T., Khondoker, M. and Moran, P. 2025. The effectiveness of the Offender Personality Disorder Pathway: a propensity score-matched analysis. Psychology, Crime and Law. 31 (6), pp. 716-736. https://doi.org/10.1080/1068316x.2024.2310532
Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression
Lisk, S., James, K., Shearer, J., Byford, S., Stallard, P., Deighton, J., Saunders, D., Yarrum, J., Fonagy, P., Weaver, T., Sclare, I., Day, C., Evans, C., Carter, B. and Brown, J. 2024. Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression. BMJ Mental Health. 27 (1). https://doi.org/10.1136/bmjment-2024-301192
Clinical effectiveness and cost-effectiveness of Structured Psychological Support for people with probable personality disorder in mental health services in England: study protocol for a randomised controlled trial
Crawford, M., Leeson, V.C., Evans, R., Goulden, N., Weaver, T., Trumm, A., Barrett. B., Khun-Thompson, F., Pandya, S.P., Saunders, K.E., Lamph, G., Woods, D., Smith, H., Greenall, T., Nicklin, V. and Barnicot, K. 2024. Clinical effectiveness and cost-effectiveness of Structured Psychological Support for people with probable personality disorder in mental health services in England: study protocol for a randomised controlled trial. BMJ Open. 14 (6). https://doi.org/10.1136/bmjopen-2024-086593
The Offender Personality Disorder (OPD) pathway for men in England and Wales: a qualitative study of pathway user views about services, perceived impact on psychological wellbeing, and implications for desistance
Jarrett, M., Trebilcock, J., Weaver, T., Forrester, A., Cambell, C., Khondoker, M., Vamvakas, G., Barrett, B. and Moran, P.A. 2024. The Offender Personality Disorder (OPD) pathway for men in England and Wales: a qualitative study of pathway user views about services, perceived impact on psychological wellbeing, and implications for desistance. Criminal Justice and Behavior. 52 (1), pp. 98-118. https://doi.org/10.1177/00938548241286829
Becoming an Open Dialogue practitioner: a qualitative study of practitioners’ training experiences and transitioning to practice
Anestis, E., Weaver, T., Melia, C., Clarke, K. and Pilling, S. 2024. Becoming an Open Dialogue practitioner: a qualitative study of practitioners’ training experiences and transitioning to practice. Frontiers in Psychology. 15, p. 1432327. https://doi.org/10.3389/fpsyg.2024.1432327
Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial.
Pilling, S., Clarke, K., Parker, G., James, K., Landau, S., Weaver, T., Razzaque, R. and Craig, T. 2022. Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial. Contemporary Clinical Trials. 113. https://doi.org/10.1016/j.cct.2021.106664
A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone
Getty, C., Weaver, T. and Metrebian, N. 2022. A qualitative exploration of patients' experience of mobile telephone‐delivered contingency management to promote adherence to supervised methadone. Drug and Alcohol Review. 42 (3), pp. 641-651. https://doi.org/10.1111/dar.13555
Causes of and alternatives to medication for behaviours that challenge in people with intellectual disabilities: direct care providers' perspectives
Deb, S., Limbu, B., Unwin, G. and Weaver, T. 2022. Causes of and alternatives to medication for behaviours that challenge in people with intellectual disabilities: direct care providers' perspectives. International Journal of Environmental Research and Public Health. 19 (16), pp. 1-14. https://doi.org/10.3390/ijerph19169988
Patients' beliefs towards contingency management: target behaviours, incentives and the remote application of these interventions
Getty, C., Weaver, T., Lynskey, M., Kirby, K., Dallery, J. and Metrebian, N. 2022. Patients' beliefs towards contingency management: target behaviours, incentives and the remote application of these interventions. Drug and Alcohol Review. 41 (1), pp. 96-105. https://doi.org/10.1111/dar.13314
Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial
Metrebian, N., Weaver, T., Goldsmith, K., Pilling, S., Hellier, J., Pickles, A., Shearer, J., Byford, S., Mitcheson, L., Bijral, P., Bogdan, N., Bowden-Jones, O., Day, E., Dunn, J., Glasper, A., Finch, E., Forshall, S., Akhtar, S., Bajaria, J., Bennett, C., Bishop, E., Charles, V., Davey, C., Desai, R., Goodfellow, C., Haque, F., Little, N., McKechnie, H., Mosler, F., Morris, J., Mutz, J., Pauli, R., Poovendran, D., Phillips, E. and Strang, J. 2021. Using a pragmatically adapted, low-cost contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial. BMJ Open. 11 (7). https://doi.org/10.1136/bmjopen-2020-046371
Evaluating the effectiveness and cost effectiveness of the ‘strengthening families, strengthening communities’ group-based parenting programme: study protocol and initial insights
Lodder, A., Mehay, A., Pavlickova, H., Hoare, Z., Box, L., Butt, J., Weaver, T., Crawford, M., Clutterbuck, D., Westbrook, N., Manning, K., Karlsen, S., Morris, S., Brand, A., Ramchandani, P., Kelly, Y., Heilmann, A. and Watt, R. 2021. Evaluating the effectiveness and cost effectiveness of the ‘strengthening families, strengthening communities’ group-based parenting programme: study protocol and initial insights. BMC Public Health. 21 (1), pp. 1-13. https://doi.org/10.1186/s12889-021-11912-4
Mobile telephone delivered contingency management for encouraging adherence to supervised methadone consumption: feasibility study for an RCT of clinical and cost-effectiveness (TIES)
Metrebian, N., Carr, E., Goldsmith, K., Weaver, T., Pilling, S., Shearer, J., Woolston-Thomas, K., Tas, B., Cooper, C., Getty, C., van der Waal, R., Kelleher, M., Finch, E., Bijral, P., Taylor, D., Scott, J. and Strang, J. 2021. Mobile telephone delivered contingency management for encouraging adherence to supervised methadone consumption: feasibility study for an RCT of clinical and cost-effectiveness (TIES). Pilot and Feasibility Studies. 7 (1), pp. 1-12. https://doi.org/10.1186/s40814-020-00761-4
A five-year prospective evaluation of a new community psychosis service in North London: introducing the Recovery and Enablement Track (RET)
Hurley, J., Jolley, S., Gibbons, O., Williams, A., Nath Varma, S., Bhandari, S., Mukherjee, K., Garraway, H., Jones, C., Aker, N., Appiah-Kusi, E. and Weaver, T. 2021. A five-year prospective evaluation of a new community psychosis service in North London: introducing the Recovery and Enablement Track (RET). Psychosis: Psychological, Social and Integrative Approaches. 13 (1), pp. 1-12. https://doi.org/10.1080/17522439.2020.1803954
Structured psychological support for people with personality disorder: feasibility randomised controlled trial of a low-intensity intervention
Crawford, M., Thana, L., Parker, J., Turner, O., Carney, A., McMurran, M., Moran, P., Weaver, T., Barrett, B., Roberts, S., Claringbold, A., Bassett, P., Sanatinia, R. and Spong, A. 2020. Structured psychological support for people with personality disorder: feasibility randomised controlled trial of a low-intensity intervention. BJPsych Open. 6 (2), pp. 1-9. https://doi.org/10.1192/bjo.2020.7
Monitoring cardiovascular disease risk inindividuals with severe mental illness in an inpatient mental health setting: a secondary data analysis.
Mwebe, H., Volante, M. and Weaver, T. 2020. Monitoring cardiovascular disease risk inindividuals with severe mental illness in an inpatient mental health setting: a secondary data analysis. British Journal of Mental Health Nursing. 9 (3), pp. 1-14. https://doi.org/10.12968/bjmh.2020.0005
Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis
Mwebe, H., Volante, M. and Weaver, T. 2020. Monitoring cardiovascular disease risk in individuals with severe mental illness in an inpatient mental health setting: a secondary data analysis. British Journal of Cardiac Nursing. 15 (11), pp. 1-15. https://doi.org/10.12968/bjca.2020.0157
Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial
Deb, S., Aimola, L., Leeson, V., Bodani, M., Li, L., Weaver, T., Sharp, D., Bassett, P. and Crawford, M. 2020. Risperidone versus placebo for aggression following traumatic brain injury: a feasibility randomised controlled trial. BMJ Open. 10 (9), pp. 1-12. https://doi.org/10.1136/bmjopen-2019-036300
Short-term PsychoEducation for Carers To Reduce Over Medication of people with intellectual disabilities (SPECTROM): study protocol
Deb, S., Limbu, B., Crawford, M. and Weaver, T. 2020. Short-term PsychoEducation for Carers To Reduce Over Medication of people with intellectual disabilities (SPECTROM): study protocol. BMJ Open. 10 (4). https://doi.org/10.1136/bmjopen-2020-037912
A systematic review of the literature regarding socially assistive robots in pre-tertiary education
Papadopoulos, R., Lazzarino, R., Miah, S., Weaver, T., Thomas, B. and Koulouglioti, C. 2020. A systematic review of the literature regarding socially assistive robots in pre-tertiary education. Computers and Education. 155. https://doi.org/10.1016/j.compedu.2020.103924
The experience of long stay in high and medium secure psychiatric hospitals in England: qualitative study of the patient perspective
Holley, J., Weaver, T. and Völlm, B. 2020. The experience of long stay in high and medium secure psychiatric hospitals in England: qualitative study of the patient perspective. International Journal of Mental Health Systems. 14 (1), pp. 1-12. https://doi.org/10.1186/s13033-020-00358-7
Randomised feasibility trial of the helping families programme-modified: an intensive parenting intervention for parents affected by severe personality difficulties
Day, C., Briskman, J., Crawford, M., Foote, L., Harris, L., Boadu, J., McCrone, P., McMurran, M., Michelson, D., Moran, P., Mosse, L., Scott, S., Stahl, D., Ramchandani, P. and Weaver, T. 2020. Randomised feasibility trial of the helping families programme-modified: an intensive parenting intervention for parents affected by severe personality difficulties. BMJ Open. 10 (2). https://doi.org/10.1136/bmjopen-2019-033637
Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness
Metrebian, N., Weaver, T., Pilling, S., Goldsmith, K., Carr, E., Shearer, J., Woolston-Thomas, K., Tas, B., Getty, C., Cooper, C., van der Waal, R., Kelleher, M., Finch, E., Bijral, P., Taylor, D., Scott, J. and Strang, J. 2020. Telephone delivered incentives for encouraging adherence to supervised methadone consumption (TIES): Study protocol for a feasibility study for an RCT of clinical and cost effectiveness. Contemporary Clinical Trials Communications. 17, pp. 1-8. https://doi.org/10.1016/j.conctc.2019.100506
The impact of involvement in mental health research on views about mental health services and service use: findings from a UK survey
Patterson, S., Trite, J. and Weaver, T. 2016. The impact of involvement in mental health research on views about mental health services and service use: findings from a UK survey. Mental Health and Addiction Research. 1 (2), pp. 47-51. https://doi.org/10.15761/MHAR.1000112
Improving health literacy about Tuberculosis among drug users. A pilot randomized controlled trial
Aceijas, C., Weaver, T., Baez-Caraballo, P., Cummings, N. and Devi Sowamber, N. 2019. Improving health literacy about Tuberculosis among drug users. A pilot randomized controlled trial. OCIMUM. https://doi.org/10.33513/ddad/1901-02
Mobile telephone-delivered contingency management interventions promoting behaviour change in individuals with substance use disorders: a meta-analysis
Getty, C., Morande, A., Lynsky, M., Weaver, T. and Metrebian, N. 2019. Mobile telephone-delivered contingency management interventions promoting behaviour change in individuals with substance use disorders: a meta-analysis. Addiction. 114 (11), pp. 1915-1925. https://doi.org/10.1111/add.14725
The Offender Personality Disorder pathway for women in England and Wales: a hopeful new development?
Cohen, R., Trebilcock, J., Weaver, T. and Moran, P. 2019. The Offender Personality Disorder pathway for women in England and Wales: a hopeful new development? Criminal Behaviour and Mental Health. 29 (5-6), pp. 257-260. https://doi.org/10.1002/cbm.2127
A more promising architecture? Commissioners’ perspectives on the reconfiguration of personality disorder services under the Offender Personality Disorder (OPD) pathway
Trebilcock, J., Jarrett, M., Weaver, T., Campbell, C., Forrester, A., Walker, J. and Moran, P. 2019. A more promising architecture? Commissioners’ perspectives on the reconfiguration of personality disorder services under the Offender Personality Disorder (OPD) pathway. Mental Health Review Journal: Research, Policy and Practice. 24 (4), pp. 306-316. https://doi.org/10.1108/MHRJ-06-2019-0021
Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial
Sheridan Rains, L., Marston, L., Hinton, M., Marwaha, S., Craig, T., Fowler, D., King, M., Omar, R., McCrone, P., Spencer, J., Taylor, J., Colman, S., Harder, C., Gilbert, E., Randhawa, A., Labuschagne, K., Jones, C., Stefanidou, T., Christoforou, M., Craig, M., Strang, J., Weaver, T. and Johnson, S. 2019. Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial. BMC Medicine. 17 (1), pp. 1-17. https://doi.org/10.1186/s12916-019-1395-5
Crisis resolution teams for people experiencing mental health crises: the CORE mixed-methods research programme including two RCTs
Lloyd-Evans, B., Christoforou, M., Osborn, D., Ambler, G., Marston, L., Lamb, D., Mason, O., Morant, N., Sullivan, S., Henderson, C., Hunter, R., Pilling, S., Nolan, F., Gray, R., Weaver, T., Kelly, K., Goater, N., Milton, A., Johnston, E., Fullarton, K., Lean, M., Paterson, B., Piotrowski, J., Davidson, M., Forsyth, R., Mosse, L., Leverton, M., O’Hanlon, P., Mundy, E., Mundy, T., Brown, E., Fahmy, S., Burgess, E., Churchard, A., Wheeler, C., Istead, H., Hindle, D. and Johnson, S. 2019. Crisis resolution teams for people experiencing mental health crises: the CORE mixed-methods research programme including two RCTs. Programme Grants for Applied Research. 7 (1), pp. 1-102. https://doi.org/10.3310/pgfar07010
Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study
Wallace, P., Andrews, M., Daley, K., Shenker, D., Gallagher, L., Watson, R., Weaver, T. and O’Donnell, A. 2017. Use of SMS texts for facilitating access to online alcohol interventions: a feasibility study. 14th annual conference of INEBRIA. New York, NY, USA 14 - 15 Sep 2017 BioMed Central. https://doi.org/10.1186/s13722-017-0087-8
Psychological Support for Personality (PSP) versus treatment as usual: study protocol for a feasibility randomized controlled trial of a low intensity intervention for people with personality disorder
Crawford, M.J., Thana, L., Parker, J., Turner, O., Xing, K.P., McMurran, M., Moran, P., Weaver, T., Barrett, B., Claringbold, A., Bassett, P. and Sanatinia, R. 2018. Psychological Support for Personality (PSP) versus treatment as usual: study protocol for a feasibility randomized controlled trial of a low intensity intervention for people with personality disorder. Trials. 19. https://doi.org/10.1186/s13063-018-2920-0
Aggression following traumatic brain injury: effectiveness of Risperidone (AFTER): study protocol for a feasibility randomised controlled trial
Deb, S., Leeson, V., Aimola, L., Bodani, M., Li, L., Weaver, T., Sharp, D. and Crawford, M. 2018. Aggression following traumatic brain injury: effectiveness of Risperidone (AFTER): study protocol for a feasibility randomised controlled trial. Trials. 19. https://doi.org/10.1186/s13063-018-2601-z
Experiences of parenting and clinical intervention for mothers affected by personality disorder: a pilot qualitative study combining parent and clinician perspectives
Wilson, R., Weaver, T., Michelson, D. and Day, C. 2018. Experiences of parenting and clinical intervention for mothers affected by personality disorder: a pilot qualitative study combining parent and clinician perspectives. BMC Psychiatry. 18 (1). https://doi.org/10.1186/s12888-018-1733-8
Positive reinforcement targeting abstinence in substance misuse (PRAISe): Study protocol for a Cluster RCT & process evaluation of contingency management
Metrebian, N., Weaver, T., Pilling, S., Hellier, J., Byford, S., Shearer, J., Mitcheson, L., Astbury, M., Bijral, P., Bogdan, N., Bowden-Jones, O., Day, E., Dunn, J., Finch, E., Forshall, S., Glasper, A., Morse, G., Akhtar, S., Bajaria, J., Bennett, C., Bishop, E., Charles, V., Davey, C., Desai, R., Goodfellow, C., Haque, F., Little, N., McKechnie, H., Morris, J., Mosler, F., Mutz, J., Pauli, R., Poovendran, D., Slater, E. and Strang, J. 2018. Positive reinforcement targeting abstinence in substance misuse (PRAISe): Study protocol for a Cluster RCT & process evaluation of contingency management. Contemporary Clinical Trials. 71, pp. 124-132. https://doi.org/10.1016/j.cct.2018.06.008
Characteristics and pathways of long-stay patients in high and medium secure settings in England; a secondary publication from a large mixed-methods study
Völlm, B., Edworthy, R., Huband, N., Talbot, E., Majid, S., Holley, J., Furtado, V., Weaver, T., McDonald, R. and Duggan, C. 2018. Characteristics and pathways of long-stay patients in high and medium secure settings in England; a secondary publication from a large mixed-methods study. Frontiers in Psychiatry. 9. https://doi.org/10.3389/fpsyt.2018.00140
A mixed-methods study exploring the characteristics and needs of long-stay patients in high and medium secure settings in England: implications for service organisation
Völlm, B., Edworthy, R., Holley, J., Talbot, E., Majid, S., Duggan, C., Weaver, T. and McDonald, R. 2017. A mixed-methods study exploring the characteristics and needs of long-stay patients in high and medium secure settings in England: implications for service organisation. Health Services and Delivery Research. 5 (11). https://doi.org/10.3310/hsdr05110
Randomised controlled trial of the clinical and cost-effectiveness of a peer-delivered self-management intervention to prevent relapse in crisis resolution team users: study protocol
Johnson, S., Mason, O., Osborn, D., Milton, A., Henderson, C., Marston, L., Ambler, G., Hunter, R., Pilling, S., Morant, N., Gray, R., Weaver, T., Nolan, F. and Lloyd-Evans, B. 2017. Randomised controlled trial of the clinical and cost-effectiveness of a peer-delivered self-management intervention to prevent relapse in crisis resolution team users: study protocol. BMJ Open. 7 (10). https://doi.org/10.1136/bmjopen-2016-015665
Feasibility trial of a psychoeducational intervention for parents with personality difficulties: The Helping Families Programme
Day, C., Briskman, J., Crawford, M., Harris, L., McCrone, P., McMurran, M., Moran, P., Morgan, L., Scott, S., Stahl, D., Ramchandani, P. and Weaver, T. 2017. Feasibility trial of a psychoeducational intervention for parents with personality difficulties: The Helping Families Programme. Contemporary Clinical Trials Communications. 8, pp. 67-74. https://doi.org/10.1016/j.conctc.2017.08.002
A randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised controlled trial
Johnson, S., Rains, L., Marwaha, S., Strang, J., Craig, T., Weaver, T., McCrone, P., King, M., Fowler, D., Pilling, S., Marston, L., Omar, R.Z., Craig, M. and Hinton, M. 2016. A randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised controlled trial. Trials. 17 (1). https://doi.org/10.1186/s13063-016-1620-x
Improving GHB withdrawal with baclofen: study protocol for a feasibility study for a randomised controlled trial
Lingford-Hughes, A., Patel, Y., Bowden-Jones, O., Crawford, M.J., Dargan, P.I., Gordon, F., Parrott, S., Weaver, T. and Wood, D.M. 2016. Improving GHB withdrawal with baclofen: study protocol for a feasibility study for a randomised controlled trial. Trials. 17. https://doi.org/10.1186/s13063-016-1593-9
Mind how you cross the gap! Outcomes for young people who failed to make the transition from child to adult services: the TRACK study
Islam, Z., Ford, T., Kramer, T., Paul, M., Parsons, H., Harley, K., Weaver, T., McLaren, S. and Singh, S. 2016. Mind how you cross the gap! Outcomes for young people who failed to make the transition from child to adult services: the TRACK study. BJPsych Bulletin. 40 (3), pp. 142-148. https://doi.org/10.1192/pb.bp.115.050690
An economic evaluation of contingency management for completion of hepatitis B vaccination in those on treatment for opiate dependence
Rafia, R., Dodd, P.J., Brennan, A., Meier, P.S., Hope, V.D., Ncube, F., Byford, S., Tie, H., Metrebian, N., Hellier, J., Weaver, T. and Strang, J. 2016. An economic evaluation of contingency management for completion of hepatitis B vaccination in those on treatment for opiate dependence. Addiction. 111 (9), pp. 1616-1627. https://doi.org/10.1111/add.13385
Hearing voices simulation: Process and outcomes of training
Patterson, S., Goulter, N. and Weaver, T. 2014. Hearing voices simulation: Process and outcomes of training. Journal of Mental Health Training, Education and Practice. 9 (1), pp. 46-58. https://doi.org/10.1108/JMHTEP-01-2013-0003
Use of contingency management incentives to improve completion of hepatitis B vaccination in people undergoing treatment for heroin dependence: a cluster randomised trial
Weaver, T., Metrebian, N., Hellier, J., Pilling, S., Charles, V., Little, N., Poovendran, D., Mitcheson, L., Ryan, F., Bowden-Jones, O., Dunn, J., Glasper, A., Finch, E. and Strang, J. 2014. Use of contingency management incentives to improve completion of hepatitis B vaccination in people undergoing treatment for heroin dependence: a cluster randomised trial. The Lancet. 384 (9938), pp. 153-163. https://doi.org/10.1016/S0140-6736(14)60196-3
Activity and views of service users involved in mental health research: UK survey
Patterson, S., Trite, J. and Weaver, T. 2014. Activity and views of service users involved in mental health research: UK survey. The British Journal of Psychiatry. 205 (1), pp. 68-75. https://doi.org/10.1192/bjp.bp.113.128637
Influences on recruitment to randomised controlled trials in mental health settings in England: a national cross-sectional survey of researchers working for the Mental Health Research Network
Borschmann, R., Patterson, S., Poovendran, D., Wilson, D. and Weaver, T. 2014. Influences on recruitment to randomised controlled trials in mental health settings in England: a national cross-sectional survey of researchers working for the Mental Health Research Network. BMC Medical Research Methodology. 14 (1). https://doi.org/10.1186/1471-2288-14-23
Monitoring and management of metabolic abnormalities: mixed-method evaluation of a successful intervention
Wilson, E., Randall, C., Patterson, S., Emmerson, B., Moudgil, V. and Weaver, T. 2014. Monitoring and management of metabolic abnormalities: mixed-method evaluation of a successful intervention. Australasian Psychiatry. 22 (3), pp. 248-253. https://doi.org/10.1177/1039856214529000
The effect of organisational resources and eligibility issues on transition from child and adolescent to adult mental health services
Belling, R., McLaren, S., Paul, M., Ford, T., Kramer, T., Weaver, T., Hovish, K., Islam, Z., White, S. and Singh, S. 2014. The effect of organisational resources and eligibility issues on transition from child and adolescent to adult mental health services. Journal of Health Services Research & Policy. 19 (3), pp. 169-176. https://doi.org/10.1177/1355819614527439
Multi-method Evaluation of the Management, Organisation and Staffing (MEMOS) in high security treatment services for people with Dangerous and Severe Personality Disorder (DSPD)
Trebilcock, J. and Weaver, T. 2010. Multi-method Evaluation of the Management, Organisation and Staffing (MEMOS) in high security treatment services for people with Dangerous and Severe Personality Disorder (DSPD). Personality Disorder Team.
Everybody knows that the prisoner is going nowhere: Parole Board members’ views about dangerous and severe personality disorder in England and Wales
Trebilcock, J. and Weaver, T. 2012. Everybody knows that the prisoner is going nowhere: Parole Board members’ views about dangerous and severe personality disorder in England and Wales. International Journal of Criminology and Sociology. 1, pp. 141-150. https://doi.org/10.6000/1929-4409.2012.01.14
‘Talking a different language’: an exploration of the influence of organizational cultures and working practices on transition from child to adult mental health services
McLaren, S., Belling, R., Paul, M., Ford, T., Kramer, T., Weaver, T., Hovish, K., Islam, Z., White, S. and Singh, S.P. 2013. ‘Talking a different language’: an exploration of the influence of organizational cultures and working practices on transition from child to adult mental health services. BMC Health Services Research. 13. https://doi.org/10.1186/1472-6963-13-254
The commissioning and provision of advocacy for problem drug users in English DATS; a cross sectional survey
Cargill, T., Weaver, T. and Patterson, S. 2012. The commissioning and provision of advocacy for problem drug users in English DATS; a cross sectional survey. Drugs: Education, Prevention, and Policy. 19 (2), pp. 163-170. https://doi.org/10.3109/09687637.2011.609204
Changing legal characteristics of dangerous and severe personality disorder (DSPD) patients and prisoners
Trebilcock, J. and Weaver, T. 2012. Changing legal characteristics of dangerous and severe personality disorder (DSPD) patients and prisoners. The Journal of Forensic Psychiatry & Psychology. 23 (2), pp. 237-243. https://doi.org/10.1080/14789949.2012.668212
‘It doesn't have to be treatable’: Mental Health Review Tribunal (MHRT) members’ views about Dangerous and Severe Personality Disorder (DSPD)
Trebilcock, J. and Weaver, T. 2012. ‘It doesn't have to be treatable’: Mental Health Review Tribunal (MHRT) members’ views about Dangerous and Severe Personality Disorder (DSPD). The Journal of Forensic Psychiatry & Psychology. 23 (2), pp. 244-260. https://doi.org/10.1080/14789949.2012.668208
Selecting outcome measures in mental health: the views of service users
Crawford, M.J., Robotham, D., Thana, L., Patterson, S., Weaver, T., Barber, R., Wykes, T. and Rose, D. 2011. Selecting outcome measures in mental health: the views of service users. Journal of Mental Health. 20 (4), pp. 336-346. https://doi.org/10.3109/09638237.2011.577114
Siblings of young people with Duchenne muscular dystrophy -- a qualitative study of impact and coping
Read, J., Kinali, M., Muntoni, F., Weaver, T. and Garralda, M.E. 2011. Siblings of young people with Duchenne muscular dystrophy -- a qualitative study of impact and coping. European Journal of Paediatric Neurology. 15 (1), pp. 21-28. https://doi.org/10.1016/j.ejpn.2010.07.006
Process, outcome and experience of transition from child to adult mental healthcare: multiperspective study
Singh, S.P., Paul, M., Ford, T., Kramer, T., Weaver, T., McLaren, S., Hovish, K., Islam, Z., Belling, R. and White, S. 2010. Process, outcome and experience of transition from child to adult mental healthcare: multiperspective study. The British Journal of Psychiatry. 197 (4), pp. 305-312. https://doi.org/10.1192/bjp.bp.109.075135
Drug service user groups: only a partial solution to the problem of developing user involvement
Patterson, S., Weaver, T. and Crawford, M. 2010. Drug service user groups: only a partial solution to the problem of developing user involvement. Drugs: Education, Prevention, and Policy. 17 (1), pp. 84-97. https://doi.org/10.3109/09687630802225495
The prevalence of personality disorder, its comorbidity with mental state disorders, and its clinical significance in community mental health teams
Newton-Howes, G., Tyrer, P., Anagnostakis, K., Cooper, S., Bowden-Jones, O. and Weaver, T. 2010. The prevalence of personality disorder, its comorbidity with mental state disorders, and its clinical significance in community mental health teams. Social Psychiatry and Psychiatric Epidemiology. 45 (4), pp. 453-460. https://doi.org/10.1007/s00127-009-0084-7
A qualitative study of illicit and non-prescribed drug use amongst people with psychotic disorders
Charles, V. and Weaver, T. 2010. A qualitative study of illicit and non-prescribed drug use amongst people with psychotic disorders. Journal of Mental Health. 19 (1), pp. 99-106. https://doi.org/10.3109/09638230802523039
Child involvement in the paediatric consultation: a qualitative study of children and carers' views
Taylor, S., Haase-Casanovas, S., Weaver, T., Kidd, J. and Garralda, E.M. 2010. Child involvement in the paediatric consultation: a qualitative study of children and carers' views. Child: Care, Health and Development. 36 (5), pp. 678-685. https://doi.org/10.1111/j.1365-2214.2010.01076.x
Delusions and qualitative confusions: a dialogic collaborative exploration
Patterson, S., Hart, J. and Weaver, T. 2010. Delusions and qualitative confusions: a dialogic collaborative exploration. Qualitative Health Research. 20 (7), pp. 1008-1018. https://doi.org/10.1177/1049732310363805
User involvement in efforts to improve the quality of drug misuse services in England: a national survey
Patterson, S., Weaver, T., Agath, K., Rutter, D., Albert, E. and Crawford, M.J. 2009. User involvement in efforts to improve the quality of drug misuse services in England: a national survey. Drugs: Education, Prevention, and Policy. 16 (4), pp. 364-377. https://doi.org/10.1080/09687630802061544
Dedicated personality disorder services: a qualitative analysis of service structure and treatment process
Price, K., Gillespie, S., Rutter, D., Dhillon, K., Gibson, S., Faulkner, A., Weaver, T. and Crawford, M.J. 2009. Dedicated personality disorder services: a qualitative analysis of service structure and treatment process. Journal of Mental Health. 18 (6), pp. 467-475. https://doi.org/10.3109/09638230902968191
'They can't solve the problem without us': a qualitative study of stakeholder perspectives on user involvement in drug treatment services in England
Patterson, S., Weaver, T., Agath, K., Albert, E., Rhodes, T., Rutter, D. and Crawford, M. 2009. 'They can't solve the problem without us': a qualitative study of stakeholder perspectives on user involvement in drug treatment services in England. Health and Social Care in the Community. 17 (1), pp. 54-62. https://doi.org/10.1111/j.1365-2524.2008.00797.x
Use and perceived utility of structured violence risk assessments in English medium secure forensic units
Khiroya, R., Weaver, T. and Maden, A. 2009. Use and perceived utility of structured violence risk assessments in English medium secure forensic units. Psychiatric Bulletin. 33 (4), pp. 129-132. https://doi.org/10.1192/pb.bp.108.019810
Transitions of care from child and adolescent mental health services to adult mental health services (TRACK study): a study of protocols in Greater London
Singh, S.P., Paul, M., Ford, T., Kramer, T. and Weaver, T. 2008. Transitions of care from child and adolescent mental health services to adult mental health services (TRACK study): a study of protocols in Greater London. BMC Health Services Research. 8 (1), pp. 1-7. https://doi.org/10.1186/1472-6963-8-135
Attitudes of staff towards patients with personality disorder in community mental health teams
Newton-Howes, G., Weaver, T. and Tyrer, P. 2008. Attitudes of staff towards patients with personality disorder in community mental health teams. Australian & New Zealand Journal of Psychiatry. 42 (7), pp. 572-577. https://doi.org/10.1080/00048670802119739
Social functioning of patients with personality disorder in secondary care
Newton-Howes, G., Tyrer, P. and Weaver, T. 2008. Social functioning of patients with personality disorder in secondary care. Psychiatric Services. 59 (9), pp. 1033-1037. https://doi.org/10.1176/ps.2008.59.9.1033
Dedicated community-based services for adults with personality disorder: Delphi study
Crawford, M.J., Price, K., Rutter, D., Moran, P., Tyrer, P., Bateman, A., Fonagy, P. and Weaver, T. 2008. Dedicated community-based services for adults with personality disorder: Delphi study. The British Journal of Psychiatry. 193 (4), pp. 342-343. https://doi.org/10.1192/bjp.bp.107.043042
Role of qualitative research to inform design of epidemiological studies: a cohort study of mental health of migrants from the former Yugoslavia
Djuretic, T., Crawford, M.J. and Weaver, T. 2007. Role of qualitative research to inform design of epidemiological studies: a cohort study of mental health of migrants from the former Yugoslavia. Journal of Mental Health. 16 (6), pp. 743-755. https://doi.org/10.1080/09638230701496394
Prevalence of personality disorder in alcohol and drug services and associated comorbidity
Bowden-Jones, O., Iqbal, M., Tyrer, P., Seivewright, N., Cooper, S., Judd, A., Weaver, T. and the COSMIC study team 2004. Prevalence of personality disorder in alcohol and drug services and associated comorbidity. Addiction. 99 (10), pp. 1306-1314. https://doi.org/10.1111/j.1360-0443.2004.00813.x
User involvement in the planning and delivery of mental health services: a cross-sectional survey of service users and providers
Crawford, M.J., Aldridge, T., Bhui, K., Rutter, D., Manley, C., Weaver, T., Tyrer, P. and Fulop, N. 2003. User involvement in the planning and delivery of mental health services: a cross-sectional survey of service users and providers. Acta Psychiatrica Scandinavica. 107 (6), pp. 410-414. https://doi.org/10.1034/j.1600-0447.2003.00049.x
Assessing the value of assertive outreach: Qualitative study of process and outcome generation in the UK700 trial
Weaver, T., Tyrer, P., Ritchie, J. and Renton, A. 2003. Assessing the value of assertive outreach: Qualitative study of process and outcome generation in the UK700 trial. The British Journal of Psychiatry. 183 (5), pp. 437-435. https://doi.org/10.1192/bjp.183.5.437
Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: prevalence and service needs in an inner London borough
Weaver, T., Rutter, D., Madden, P., Ward, J., Stimson, G. and Renton, A. 2001. Results of a screening survey for co-morbid substance misuse amongst patients in treatment for psychotic disorders: prevalence and service needs in an inner London borough. Social Psychiatry and Psychiatric Epidemiology. 36 (8), pp. 399-406. https://doi.org/10.1007/s001270170030
The prevalence and management of co-morbid substance misuse and mental illness: results of a screening survey in substance misuse and mental health treatment populations
Weaver, T., Hickman, M., Rutter, D., Ward, J., Stimson, G. and Renton, A. 2001. The prevalence and management of co-morbid substance misuse and mental illness: results of a screening survey in substance misuse and mental health treatment populations. Drug and Alcohol Review. 20 (4), pp. 407-416. https://doi.org/10.1080/09595230120092724
Residents' perceptions of water quality improvements following remediation work in the Pymme's Brook catchment, north London, UK
Faulkner, H., Green, A., Pellaumail, K. and Weaver, T. 2001. Residents' perceptions of water quality improvements following remediation work in the Pymme's Brook catchment, north London, UK. Journal of Environmental Management. 62 (3), pp. 239-254. https://doi.org/10.1006/jema.2001.0435
The Bentham unit: a pilot remand and assessment service for male mentally disordered remand prisoners. II: Report of an independent evaluation
Weaver, T., Taylor, F., Cunningham, B. and Maden, A. 1997. The Bentham unit: a pilot remand and assessment service for male mentally disordered remand prisoners. II: Report of an independent evaluation. The British Journal of Psychiatry. 170 (5), pp. 462-466. https://doi.org/10.1192/bjp.170.5.462