Youths are less susceptible to exercise-induced muscle damage than adults; a systematic review with meta-analysis

Article


Fernandes, J., Hayes, L., Dingley, A., Moeskops, S., Oliver, J., Arede, J., Twist, C. and Wilson, L. 2023. Youths are less susceptible to exercise-induced muscle damage than adults; a systematic review with meta-analysis. Pediatric Exercise Science. https://doi.org/10.1123/pes.2023-0108
TypeArticle
TitleYouths are less susceptible to exercise-induced muscle damage than adults; a systematic review with meta-analysis
AuthorsFernandes, J., Hayes, L., Dingley, A., Moeskops, S., Oliver, J., Arede, J., Twist, C. and Wilson, L.
Abstract

Purpose; This meta-analysis aimed to 1) provide a comparison of peak changes in indirect markers of EIMD in youths versus adults and 2) determine if the involved limb moderated this effect. Method; Studies were eligible for inclusion if they 1) provided a human youth versus adult comparison, 2) provided data on muscle strength, soreness or creatine kinase (CK) markers beyond ≥ 24 hours, 3) did not provide a recovery treatment. Effect sizes (ES) were presented alongside 95% confidence intervals. Results; EIMD exhibited larger effects on adults than in youths for muscle strength (ES=-2.01; P<0.001), muscle soreness (ES=-1.52; P<0.001) and CK (ES=-1.98; P<0.001). The random effects meta-regression examined the effects of upper- and lower-limb exercise in youths and adults was significant for muscle soreness (coefficient estimate =1.11; P< 0.001) but not muscle strength or CK (P>0.05). As such, the between-group effects for muscle soreness (ES=-2.10 versus -1.03; P<0.05) were greater in the upper- than lower-limb. Conclusion; The magnitude of EIMD in youths is substantially less than their adult counterparts, and this effect is greater in upper- than lower-limbs for muscle soreness. These findings help guide practitioners who may be concerned about the potential impact of EIMD when training youth athletes.

Keywordseccentric exercise; muscle strength; soreness; creatine kinase
Sustainable Development Goals3 Good health and well-being
Middlesex University ThemeHealth & Wellbeing
LanguageEnglish
PublisherHuman Kinetics
JournalPediatric Exercise Science
ISSN0899-8493
Electronic1543-2920
Publication dates
Online08 Dec 2023
Publication process dates
AcceptedSep 2023
Deposited20 Nov 2023
Output statusPublished
Accepted author manuscript
File Access Level
Open
Copyright Statement

Accepted author manuscript version reprinted, by permission, from Pediatric Exercise Science , 2023, https://doi.org/10.1123/pes.2023-0108 . © Human Kinetics, Inc.

Digital Object Identifier (DOI)https://doi.org/10.1123/pes.2023-0108
Web of Science identifierWOS:001123673500001
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