Molecular Biology group


TitleMolecular Biology group

Latest research outputs

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Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ
Burczynska, B., Kobrouly, L., Butler, S., Naase, M. and Iles, R. 2014. Novel insights into the expression of CGB1 & 2 genes by epithelial cancer cell lines secreting ectopic free hCGβ. Anticancer Research. 34 (5), pp. 2239-2248.

Article

UVA-induced carbon-centered radicals in lightly pigmented cells detected using ESR spectroscopy
Kassouf, N., Kay, C., Volkov, A., Chiang, S., Birch-Machin, M., El-Khamisy, S. and Haywood, R. 2018. UVA-induced carbon-centered radicals in lightly pigmented cells detected using ESR spectroscopy. Free Radical Biology and Medicine. 126, pp. 153-165. https://doi.org/10.1016/j.freeradbiomed.2018.07.019

Article

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage
Chiang, S., Meagher, M., Kassouf, N., Hafezparast, M., McKinnon, P., Haywood, R. and El-Khamisy, S. 2017. Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage. Science Advances. 3 (4). https://doi.org/10.1126/sciadv.1602506

Article

Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins
Haywood, R., Andrady, C., Kassouf, N. and Sheppard, N. 2011. Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins. Photochemistry and Photobiology. 87 (1), pp. 117-130. https://doi.org/10.1111/j.1751-1097.2010.00850.x

Article

Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers
Irshad, S., Mahul-Mellier, A., Kassouf, N., Lemarie, A. and Grimm, S. 2009. Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers. Cell Death and Differentiation. 16 (6), pp. 890-898. https://doi.org/10.1038/cdd.2009.21

Article

Implications of spatial genetic patterns for conserving African leopards
Ropiquet, A., Knight, A., Born, C., Martins, Q., Balme, G., Kirkendall, L., Hunter, L., Senekal, C. and Matthee, C. 2015. Implications of spatial genetic patterns for conserving African leopards. Comptes Rendus Biologies. 338 (11), pp. 728-737. https://doi.org/10.1016/j.crvi.2015.06.019

Article

Biological water quality assessment in running water sites harbouring the endangered crayfish, Austropotamobius pallipes based on macroinvertebrates and its potential in habitat selection for restocking
Grandjean, F., Jouteux, R., Ropiquet, A., Bachelier, E. and Bramard, M. 2001. Biological water quality assessment in running water sites harbouring the endangered crayfish, Austropotamobius pallipes based on macroinvertebrates and its potential in habitat selection for restocking. in: Whisson, E. (ed.) Freshwater Crayfish.XIII Perth, Australia Freshwater Crayfish.XIII.

Book chapter

Combining multiple autosomal introns for studying shallow phylogeny and taxonomy of Laurasiatherian mammals: application to the tribe Bovini (Cetartiodactyla, Bovidae)
Hassanin, A., An, J., Ropiquet, A., Nguyen, T. and Couloux, A. 2013. Combining multiple autosomal introns for studying shallow phylogeny and taxonomy of Laurasiatherian mammals: application to the tribe Bovini (Cetartiodactyla, Bovidae). Molecular Phylogenetics and Evolution. 66 (3), pp. 766-775. https://doi.org/10.1016/j.ympev.2012.11.003

Article

Has the kouprey (Bos Sauveli Urbain, 1937) been domesticated in Cambodia? = Le kouprey (Bos sauveli Urbain, 1937) a-t-il été domestiqué au Cambodge?
Hassanin, A., Ropiquet, A., Cornette, R., Tranier, M., Pfeffer, P., Candegabe, P. and Lemaire, M. 2006. Has the kouprey (Bos Sauveli Urbain, 1937) been domesticated in Cambodia? = Le kouprey (Bos sauveli Urbain, 1937) a-t-il été domestiqué au Cambodge? Comptes Rendus Biologies. 329 (2), pp. 124-135. https://doi.org/10.1016/j.crvi.2005.11.003

Article

What is the taxonomic status of the Cambodian banteng and does it have close genetic links with the kouprey?
Hassanin, A. and Ropiquet, A. 2006. What is the taxonomic status of the Cambodian banteng and does it have close genetic links with the kouprey? Journal of Zoology. 271 (3), pp. 246-252. https://doi.org/10.1111/j.1469-7998.2006.00272.x

Article

Molecular phylogeny of the tribe Bovini (Bovidae, Bovinae) and the taxonomic status of the Kouprey, Bos Sauveli Urbain 1937
Hassanin, A. and Ropiquet, A. 2004. Molecular phylogeny of the tribe Bovini (Bovidae, Bovinae) and the taxonomic status of the Kouprey, Bos Sauveli Urbain 1937. Molecular Phylogenetics and Evolution. 33 (3), pp. 896-907. https://doi.org/10.1016/j.ympev.2004.08.009

Article

Molecular phylogeny of caprines (Bovidae, Antilopinae): the question of their origin and diversification during the Miocene
Ropiquet, A. and Hassanin, A. 2005. Molecular phylogeny of caprines (Bovidae, Antilopinae): the question of their origin and diversification during the Miocene. Journal of Zoological Systematics and Evolutionary Research. 43 (1), pp. 49-60. https://doi.org/10.1111/j.1439-0469.2004.00290.x

Article

Molecular evidence for the polyphyly of the genus Hemitragus (Mammalia, Bovidae)
Ropiquet, A. and Hassanin, A. 2005. Molecular evidence for the polyphyly of the genus Hemitragus (Mammalia, Bovidae). Molecular Phylogenetics and Evolution. 36 (1), pp. 154-168. https://doi.org/10.1016/j.ympev.2005.01.002

Article

Mitochondrial and nuclear phylogenies of Cervidae (Mammalia, Ruminantia): systematics, morphology, and biogeography
Gilbert, C., Ropiquet, A. and Hassanin, A. 2006. Mitochondrial and nuclear phylogenies of Cervidae (Mammalia, Ruminantia): systematics, morphology, and biogeography. Molecular Phylogenetics and Evolution. 40 (1), pp. 101-117. https://doi.org/10.1016/j.ympev.2006.02.017

Article

Hybrid origin of the Pliocene ancestor of wild goats
Ropiquet, A. and Hassanin, A. 2006. Hybrid origin of the Pliocene ancestor of wild goats. Molecular Phylogenetics and Evolution. 41 (2), pp. 395-404. https://doi.org/10.1016/j.ympev.2006.05.033

Article

Resolving a zoological mystery: the kouprey is a real species
Hassanin, A. and Ropiquet, A. 2007. Resolving a zoological mystery: the kouprey is a real species. Proceedings of the Royal Society B: Biological Sciences. 274 (1627), pp. 2849-2855. https://doi.org/10.1098/rspb.2007.0830

Article

Mitochondrial DNA variability in Giraffa Camelopardalis: consequences for taxonomy, phylogeography and conservation of giraffes in West and Central Africa
Hassanin, A., Ropiquet, A., Gourmand, A., Chardonnet, B. and Rigoulet, J. 2007. Mitochondrial DNA variability in Giraffa Camelopardalis: consequences for taxonomy, phylogeography and conservation of giraffes in West and Central Africa. Comptes Rendus Biologies. 330 (3), pp. 265-274. https://doi.org/10.1016/j.crvi.2007.02.008

Article

Low genetic variability of the white-clawed crayfish in the Iberian Peninsula: its origin and management implications
Diéguez-Uribeondo, J., Royo, F., Souty-Grosset, C., Ropiquet, A. and Grandjean, F. 2008. Low genetic variability of the white-clawed crayfish in the Iberian Peninsula: its origin and management implications. Aquatic Conservation: Marine and Freshwater Ecosystems. 18 (1), pp. 19-31. https://doi.org/10.1002/aqc.811

Article

SuperTRI: a new approach based on branch support analyses of multiple independent data sets for assessing reliability of phylogenetic inferences
Ropiquet, A., Li, B. and Hassanin, A. 2009. SuperTRI: a new approach based on branch support analyses of multiple independent data sets for assessing reliability of phylogenetic inferences. Comptes Rendus Biologies. 332 (9), pp. 832-847. https://doi.org/10.1016/j.crvi.2009.05.001

Article

Evolution of the mitochondrial genome in mammals living at high altitude: new insights from a study of the tribe Caprini (Bovidae, Antilopinae)
Hassanin, A., Ropiquet, A., Couloux, A. and Cruaud, C. 2009. Evolution of the mitochondrial genome in mammals living at high altitude: new insights from a study of the tribe Caprini (Bovidae, Antilopinae). Journal of Molecular Evolution. 68 (4), pp. 293-310. https://doi.org/10.1007/s00239-009-9208-7

Article

Genetic variability of Austropotamobius Italicus in the Marches region: implications for conservation
Cataudella, R., Paolucci, M., Delaunay, C., Ropiquet, A., Hassanin, A., Balsamo, M. and Grandjean, F. 2010. Genetic variability of Austropotamobius Italicus in the Marches region: implications for conservation. Aquatic Conservation: Marine and Freshwater Ecosystems. 20 (3), pp. 261-268. https://doi.org/10.1002/aqc.1099

Article

Pattern and timing of diversification of Cetartiodactyla (Mammalia, Laurasiatheria), as revealed by a comprehensive analysis of mitochondrial genomes = Histoire évolutive des Cetartiodactyla (Mammalia, Laurasiatheria) racontée par l’analyse des génomes mitochondriaux
Hassanin, A., Delsuc, F., Ropiquet, A., Hammer, C., Jansen van Vuuren, B., Matthee, C., Ruiz-Garcia, M., Catzeflis, F., Areskoug, V., Nguyen, T. and Couloux, A. 2012. Pattern and timing of diversification of Cetartiodactyla (Mammalia, Laurasiatheria), as revealed by a comprehensive analysis of mitochondrial genomes = Histoire évolutive des Cetartiodactyla (Mammalia, Laurasiatheria) racontée par l’analyse des génomes mitochondriaux. Comptes Rendus Biologies. 335 (1), pp. 32-50. https://doi.org/10.1016/j.crvi.2011.11.002

Article

Cryptic speciation and chromosomal repatterning in the South African climbing mice Dendromus (Rodentia, Nesomyidae)
Solano, E., Taylor, P., Rautenbach, A., Ropiquet, A. and Castiglia, R. 2014. Cryptic speciation and chromosomal repatterning in the South African climbing mice Dendromus (Rodentia, Nesomyidae). PLoS ONE. 9 (2), pp. 1-9. https://doi.org/10.1371/journal.pone.0088799

Article

Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2+ elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets
Kassouf, N., Ambily, A., Watson, S., Hassock, S., Authi, H., Srivastava, S., Watson, S. and Authi, K. 2015. Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca2+ elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets. Cellular Signalling. 27 (7), pp. 1488-1498. https://doi.org/10.1016/j.cellsig.2015.03.008

Article

The role of plasma membrane STIM1 and Ca2+entry in platelet aggregation. STIM1 binds to novel proteins in human platelets
Ambily, A., Kaiser, W., Pierro, C., Chamberlain, E., Li, Z., Jones, C., Kassouf, N., Gibbins, J. and Authi, K. 2014. The role of plasma membrane STIM1 and Ca2+entry in platelet aggregation. STIM1 binds to novel proteins in human platelets. Cellular Signalling. 26 (3), pp. 502-511. https://doi.org/10.1016/j.cellsig.2013.11.025

Article

Lentiviral vector transduction of spermatozoa as a tool for the study of early development
Chandrashekran, A., Isa, I., Dudhia, J., Thrasher, A., Dibb, N., Casimir, C., Readhead, C. and Winston, R. 2014. Lentiviral vector transduction of spermatozoa as a tool for the study of early development. FEBS Open Bio. 4 (1), pp. 266-275. https://doi.org/10.1016/j.fob.2014.02.008

Article

Efficient generation of transgenic mice by lentivirus-mediated modification of spermatozoa
Chandrashekran, A., Sarkar, R., Thrasher, A., Fraser, S., Dibb, N., Casimir, C., Winston, R. and Readhead, C. 2014. Efficient generation of transgenic mice by lentivirus-mediated modification of spermatozoa. The FASEB Journal. 28 (2), pp. 569-576. https://doi.org/10.1096/fj.13-233999

Article

A novel treatment strategy for ovarian cancer based on immunization against zona pellucida protein (ZP) 3
Rahman, N., Bennink, H., Chrusciel, M., Sharp, V., Zimmerman, Y., Dina, R., Li, X., Ellonen, A., Rivero-Müller, A., Dilworth, S., Ghaem-Maghami, S., Vainio, O. and Huhtaniemi, I. 2012. A novel treatment strategy for ovarian cancer based on immunization against zona pellucida protein (ZP) 3. The FASEB Journal. 26 (1), pp. 324-333. https://doi.org/10.1096/fj.11-192468

Article

A functional interaction between RIP140 and PGC-1α regulates the expression of the lipid droplet protein CIDEA
Hallberg, M., Morganstein, D., Kiskinis, E., Shah, K., Kralli, A., Dilworth, S., White, R., Parker, M. and Christian, M. 2008. A functional interaction between RIP140 and PGC-1α regulates the expression of the lipid droplet protein CIDEA. Molecular and cellular biology. 28 (22), pp. 6785-6795. https://doi.org/10.1128/MCB.00504-08

Article

Polyoma virus middle T antigen and its role in identifying cancer-related molecules
Dilworth, S. 2002. Polyoma virus middle T antigen and its role in identifying cancer-related molecules. Nature Reviews Cancer. 2 (12), pp. 951-956. https://doi.org/10.1038/nrc946

Article

Switching on kinases: oncogenic activation of BRAF and the PDGFR family
Dibb, N., Dilworth, S. and Mol, C. 2004. Switching on kinases: oncogenic activation of BRAF and the PDGFR family. Nature Reviews Cancer. 4 (9), pp. 718-727. https://doi.org/10.1038/nrc1434

Article

Abnormal preantral folliculogenesis in polycystic ovaries is associated with increased granulosa cell division
Stubbs, S., Stark, J., Dilworth, S., Franks, S. and Hardy, K. 2007. Abnormal preantral folliculogenesis in polycystic ovaries is associated with increased granulosa cell division. The Journal of Clinical Endocrinology and Metabolism. 92 (11), pp. 4418-4426. https://doi.org/10.1210/jc.2007-0729

Article

Rapid activation of ATM on DNA flanking double-strand breaks
You, Z., Bailis, J., Johnson, S., Dilworth, S. and Hunter, T. 2007. Rapid activation of ATM on DNA flanking double-strand breaks. Nature Cell Biology. 9 (11), pp. 1311-1318. https://doi.org/10.1038/ncb1651

Article

RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes
Kiskinis, E., Hallberg, M., Christian, M., Olofsson, M., Dilworth, S., White, R. and Parker, M. 2007. RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes. The EMBO Journal. 26 (23), pp. 4831-4840. https://doi.org/10.1038/sj.emboj.7601908

Article

Polyoma virus and simian virus 40 as cancer models: history and perspectives
Atkin, S., Griffin, B. and Dilworth, S. 2009. Polyoma virus and simian virus 40 as cancer models: history and perspectives. Seminars in Cancer Biology. 19 (4), pp. 211-217. https://doi.org/10.1016/j.semcancer.2009.03.001

Article

Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways
Rider, M., Hussain, N., Dilworth, S. and Storey, K. 2009. Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways. Molecular and Cellular Biochemistry. 332 (1-2), pp. 207-213. https://doi.org/10.1007/s11010-009-0193-3

Article

AMP-activated protein kinase and metabolic regulation in cold-hardy insects
Rider, M., Hussain, N., Dilworth, S., Storey, J. and Storey, K. 2011. AMP-activated protein kinase and metabolic regulation in cold-hardy insects. Journal of Insect Physiology. 57 (11), pp. 1453-1462. https://doi.org/10.1016/j.jinsphys.2011.07.006

Article

Polyomavirus middle T-antigen is a transmembrane protein that binds signaling proteins in discrete subcellular membrane sites
Zhou, A., Ichaso, N., Adamarek, A., Zila, V., Forstova, J., Dibb, N. and Dilworth, S. 2011. Polyomavirus middle T-antigen is a transmembrane protein that binds signaling proteins in discrete subcellular membrane sites. Journal of Virology. 85 (7), pp. 3046-3054. https://doi.org/10.1128/JVI.02209-10

Article

Dyskeratosis congenita and the DNA damage response
Kirwan, M., Beswick, R., Walne, A., Hossain, U., Casimir, C., Vulliamy, T. and Dokal, I. 2011. Dyskeratosis congenita and the DNA damage response. British Journal of Haematology. 153 (5), pp. 634-643. https://doi.org/10.1111/j.1365-2141.2011.08679.x

Article

Examination of hemiplasy, homoplasy and phylogenetic discordance in chromosomal evolution of the Bovidae
Robinson, T. and Ropiquet, A. 2011. Examination of hemiplasy, homoplasy and phylogenetic discordance in chromosomal evolution of the Bovidae. Systematic Biology. 60 (4), pp. 439-450. https://doi.org/10.1093/sysbio/syr045

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