ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair
Article
Stordal, B. and Davey, R. 2009. ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair. Cancer Chemotherapy and Pharmacology. 63 (4), pp. 661-672. https://doi.org/10.1007/s00280-008-0783-x
Type | Article |
---|---|
Title | ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair |
Authors | Stordal, B. and Davey, R. |
Abstract | Background: The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather the resistant cell lines have a cell cycle alteration allowing them to rapidly proliferate post drug treatment. |
Keywords | Cisplatin; Oxaliplatin; Resistance; Cell cycle; DNA repair; ERCC1; RAD51B; p21; Small cell lung cancer |
Research Group | Biomarkers for Cancer group |
Publisher | Springer |
Journal | Cancer Chemotherapy and Pharmacology |
ISSN | 0344-5704 |
Electronic | 1432-0843 |
Publication dates | |
Online | 25 Jun 2008 |
01 Mar 2009 | |
Publication process dates | |
Deposited | 28 Apr 2015 |
Accepted | 02 Jun 2008 |
Output status | Published |
Accepted author manuscript | |
Copyright Statement | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use (https://www.springernature.com/gp/open-research/policies/accepted-ma...) , but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00280-008-0783-x |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s00280-008-0783-x |
PubMed ID | 18575867 |
Web of Science identifier | WOS:000264114300011 |
Language | English |
https://repository.mdx.ac.uk/item/85292
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