BRCA1 promoter methylation and clinical outcomes in epithelial ovarian cancer a pooled analysis of individual patient data
Conference item
Kalachand, R., Stordal, B., Madden, S., Chandler, B., Cunningham, J., Goode, E., Ruscito, I., Braicu, E., Sehouli, J., Ignatov, A., Yu, H., Katsaros, D., Lu, L., Mills, G., Broaddus, R., Lu, K., Carey, M., Timms, K., Rzepecka, I., Kupryjanczyk, J., Swisher, E., Harrell, M., Agnew, K., O'Riain, C., O'Toole, S., O'Leary, J., Thomas, D., Chaudhry, P., Srinivasan, R. and Hennessy, B. 2019. BRCA1 promoter methylation and clinical outcomes in epithelial ovarian cancer a pooled analysis of individual patient data. Lorne Cancer Conference. Lorne, Victoria, Australia 14 - 16 Feb 2019
Title | BRCA1 promoter methylation and clinical outcomes in epithelial ovarian cancer a pooled analysis of individual patient data |
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Authors | Kalachand, R., Stordal, B., Madden, S., Chandler, B., Cunningham, J., Goode, E., Ruscito, I., Braicu, E., Sehouli, J., Ignatov, A., Yu, H., Katsaros, D., Lu, L., Mills, G., Broaddus, R., Lu, K., Carey, M., Timms, K., Rzepecka, I., Kupryjanczyk, J., Swisher, E., Harrell, M., Agnew, K., O'Riain, C., O'Toole, S., O'Leary, J., Thomas, D., Chaudhry, P., Srinivasan, R. and Hennessy, B. |
Abstract | Importance: BRCA1 promoter methylation has been proposed as a mechanism of homologous recombination deficiency in epithelial ovarian cancer (EOC). Studies evaluating BRCA1-methylated EOC (BMEOC) do not consistently support improved survival outcomes following platinum chemotherapy. |
Sustainable Development Goals | 3 Good health and well-being |
Research Group | Biomarkers for Cancer group |
Conference | Lorne Cancer Conference |
Publication dates | |
15 Feb 2019 | |
Publication process dates | |
Deposited | 07 Jul 2022 |
Accepted | 06 Dec 2018 |
Output status | Published |
Language | English |
https://repository.mdx.ac.uk/item/89x6v
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