Biomarkers for Cancer group


TitleBiomarkers for Cancer group

Latest research outputs

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Mechanisms of apoptosis and autophagy in chemoresistant ovarian cancer cells [Presentation]
Bennacer, A., Roberts, H. and Stordal, B. 2018. Mechanisms of apoptosis and autophagy in chemoresistant ovarian cancer cells [Presentation]. 2018 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 04 Sep 2018

Conference item

Biomedical Science Exchanges [Presentation]
Stordal, B. 2018. Biomedical Science Exchanges [Presentation]. Middlesex University’s Erasmus Staff Training Week 2018. Middlesex University London

Conference item

Biomedical Science Exchanges [Presentation]
Stordal, B. 2018. Biomedical Science Exchanges [Presentation]. Middlesex University Staff Conference 2018: Learning through Change. Middlesex University London 27 Mar 2018

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Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: Diagnostics guidance [DG34]
Nixon, F., Albrow, R., Donna, B., Kroese, D., Adair, E., Bagshaw, J., Carrol, E., Driskell, O., Edwards, S., Fleming, S., Gray, J., Halligan, S., Hitchman, J., Hyde, C., McGinley, P., Messenger, M., Moseley, A., Naylor, P., Neely, D., Rahman Haley, S., Richards, S., Sculpher, M., Stevenson, M., Summerton, N., Wierzbicki, A., Bramley, M., Graham, J., Pepper, L., Ryyan, D., Stordal, B., Van Mann, U. and Wardley, A. 2018. Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: Diagnostics guidance [DG34]. NICE.

Technical report

Overcoming chemoresistance in osteosarcoma: the role of autophagy in cell death or survival following chemotherapy
Rosa, G., Burczynska, B., Stordal, B. and Roberts, H. 2018. Overcoming chemoresistance in osteosarcoma: the role of autophagy in cell death or survival following chemotherapy. 2018 NCRI Cancer Conference. Glasgow, Scotland 04 - 06 Nov 2018

Conference poster

ROR1- A biomarker for chemoresistance in ovarian cancer
Syed, E., Hills, F. and Stordal, B. 2018. ROR1- A biomarker for chemoresistance in ovarian cancer. 2018 NCRI Cancer Conference. Glasgow, Scotland 04 - 06 Nov 2018

Conference poster

Method optimisation for identification of carbohydrate moieties on human chorionic gonadotropin glycoforms using MALDI-TOF-MS
Gondek, M., Burczynska, B. and Hills, F. 2018. Method optimisation for identification of carbohydrate moieties on human chorionic gonadotropin glycoforms using MALDI-TOF-MS. 45th International Society of Oncology and BioMarkers (ISOBM) 2018 Congress. Hamburg, Germany 24 - 27 Nov 2018

Conference poster

UVA-induced carbon-centered radicals in lightly pigmented cells detected using ESR spectroscopy
Kassouf, N., Kay, C., Volkov, A., Chiang, S., Birch-Machin, M., El-Khamisy, S. and Haywood, R. 2018. UVA-induced carbon-centered radicals in lightly pigmented cells detected using ESR spectroscopy. Free Radical Biology and Medicine. 126, pp. 153-165. https://doi.org/10.1016/j.freeradbiomed.2018.07.019

Article

Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer [Protocol - Intervention]
Stordal, B., Kalachand, R. and Hall, N. 2018. Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer [Protocol - Intervention]. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd008766.pub2

Article

Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine
Kvirkvelia, N., Chikadze, N., Makinde, J., McBride, J., Porakishvili, N., Hills, F., Martensen, P., Justesen, J., Delves, P., Lund, T. and Roitt, I. 2018. Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine. Clinical & Experimental Immunology. 193 (1), pp. 73-83. https://doi.org/10.1111/cei.13131

Article

Analysis of procainamide-derivatised heparan sulphate disaccharides in biological samples using hydrophilic interaction liquid chromatography mass spectrometry
Antia, I., Mathew, K., Yagnik, D., Hills, F. and Shah, A. 2018. Analysis of procainamide-derivatised heparan sulphate disaccharides in biological samples using hydrophilic interaction liquid chromatography mass spectrometry. Analytical and Bioanalytical Chemistry. 410 (1), pp. 131-143. https://doi.org/10.1007/s00216-017-0703-1

Article

Recovery following a marathon: a comparison of cold water immersion, whole body cryotherapy and a placebo control
Wilson, L., Cockburn, E., Paice, K., Sinclair, S., Faki, T., Hills, F., Gondek, M., Wood, A. and Dimitriou, L. 2018. Recovery following a marathon: a comparison of cold water immersion, whole body cryotherapy and a placebo control. European Journal of Applied Physiology. 118 (1), pp. 153-163. https://doi.org/10.1007/s00421-017-3757-z

Article

Platelet activating acetylhydrolase involved in inflammation resolution in macrophages and neutrophils which have been stimulated with urate crystals
Yagnik, D. 2015. Platelet activating acetylhydrolase involved in inflammation resolution in macrophages and neutrophils which have been stimulated with urate crystals. The 12th World Congress on Inflammation. Boston, USA 08 - 12 Aug 2015 Springer. https://doi.org/10.1007/s00011-015-0839-4

Conference paper

CD10−/ALDH− cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy
Ffrench, B., Gasch, C., Hokamp, K., Spillane, C., Blackshields, G., Mahgoub, T., Bates, M., Kehoe, L., Mooney, A., Doyle, R., Doyle, B., O'Donnell, D., Gleeson, N., Hennessy, B., Stordal, B., O'Riain, C., Lambkin, H., O'Toole, S., O'Leary, J. and Gallagher, M. 2017. CD10−/ALDH− cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy. Cell Death & Disease. 8 (10). https://doi.org/10.1038/cddis.2017.379

Article

Comparative selection strategies for development of platinum-drug resistant ovarian cancer cell lines
Busschots, S., Kalachand, R., O'Toole, S., O'Leary, J., Hennessy, B. and Stordal, B. 2017. Comparative selection strategies for development of platinum-drug resistant ovarian cancer cell lines. 12th International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy. Sydney, Australia 10 - 14 Dec 2017

Conference item

Detection and quantification of human chorionic gonadotropin levels in human placental choriocarcinoma cell lines
Gondek, M., Hills, F. and Burczynska, B. 2017. Detection and quantification of human chorionic gonadotropin levels in human placental choriocarcinoma cell lines. 2017 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 28 - 29 Jun 2017

Conference poster

The effect of plasma volume on changes in biomarkers of muscle damage, inflammation, oxidative stress and leukocyte differentialfollowing a 42.2 km trail run, and the efficacy of recovery interventions
Cockburn, E., Hills, F., Wilson, L., Paice, K., Wood, A. and Dimitriou, L. 2017. The effect of plasma volume on changes in biomarkers of muscle damage, inflammation, oxidative stress and leukocyte differentialfollowing a 42.2 km trail run, and the efficacy of recovery interventions. BASES-FEPSAC Conference 2017. Nottingham, UK 28 - 29 Nov 2017 Taylor & Francis (Routledge). pp. s26

Conference poster

Influence of cold water immersion and cherry juice on recovery following a 42.2km trail run
Paice, K., Dimitriou, L., Wilson, L., Hills, F., Sinclair, S., Gondek, M., Kwan Xue Bin, X., Wood, A. and Cockburn, E. 2017. Influence of cold water immersion and cherry juice on recovery following a 42.2km trail run. BASES-FEPSAC Conference 2017. Nottingham, UK 28 - 29 Nov 2017 Taylor & Francis (Routledge). pp. s92

Conference poster

The influence of cold water immersion on markers of recovery following resistance exercise
Wilson, L., Dimitriou, L., Hills, F., Gondek, M. and Cockburn, E. 2017. The influence of cold water immersion on markers of recovery following resistance exercise. BASES-FEPSAC Conference 2017. Nottingham, UK 28 - 29 Nov 2017 Taylor & Francis (Routledge). pp. s66

Conference poster

Modelling and validating three dimensional human normal cervix and cervical cancer tissues in vitro
Zuk, A., Wen, S., Dilworth, S., Li, D. and Ghali, L. 2017. Modelling and validating three dimensional human normal cervix and cervical cancer tissues in vitro. Journal of Biomedical Research. 31 (3), pp. 240-247. https://doi.org/10.7555/JBR.31.20160150

Article

Heparan sulfate disaccharide measurement from biological samples using pre-column derivatization, UPLC-MS and single ion monitoring
Antia, I., Yagnik, D., Pantoja Munoz, L., Shah, A. and Hills, F. 2017. Heparan sulfate disaccharide measurement from biological samples using pre-column derivatization, UPLC-MS and single ion monitoring. Analytical Biochemistry. 530, pp. 17-30. https://doi.org/10.1016/j.ab.2017.04.019

Article

Lipoxin A4 selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression
Simoes, R., De-Brito, N., Cunha-Costa, H., Morandi, V., Fierro, I., Roitt, I. and Barja-Fidalgo, C. 2017. Lipoxin A4 selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression. International Journal of Cancer. 140 (2), pp. 346-357. https://doi.org/10.1002/ijc.30424

Article

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage
Chiang, S., Meagher, M., Kassouf, N., Hafezparast, M., McKinnon, P., Haywood, R. and El-Khamisy, S. 2017. Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage. Science Advances. 3 (4). https://doi.org/10.1126/sciadv.1602506

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Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins
Haywood, R., Andrady, C., Kassouf, N. and Sheppard, N. 2011. Intensity-dependent direct solar radiation- and UVA-induced radical damage to human skin and DNA, lipids and proteins. Photochemistry and Photobiology. 87 (1), pp. 117-130. https://doi.org/10.1111/j.1751-1097.2010.00850.x

Article

The role of ectopic human chorionic gonadotropin beta subunit in inducing epithelial mesenchymal transition in human keratinocytes and its possible pathways
Wen, S., Li, D., Farshori, Z., Wang, X. and Ghali, L. 2015. The role of ectopic human chorionic gonadotropin beta subunit in inducing epithelial mesenchymal transition in human keratinocytes and its possible pathways. British Pharmacological Society Winder Conference 2014. Queen Elizabeth II Conference Centre London 14 - 17 Dec 2014

Conference poster

Identification of genomic markers correlated with sensitivity in solid tumors to Dasatinib using sparse principal components
Hossain, A. and Khan, H. 2016. Identification of genomic markers correlated with sensitivity in solid tumors to Dasatinib using sparse principal components. Journal of Applied Statistics. 43 (14), pp. 2538-2549. https://doi.org/10.1080/02664763.2016.1142941

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Optimizing drug delivery using arsenic trioxide encapsulated liposomes for increasing the efficacy in treating cervical cancer in vitro
Akhtar, A., Wen, S., Wang, X., Ghali, L. and Bell, C. 2016. Optimizing drug delivery using arsenic trioxide encapsulated liposomes for increasing the efficacy in treating cervical cancer in vitro. International Conference on Nanomedicine and Nanobiotechnology 2016 – ICONAN 2016. Paris, France 28 - 30 Sep 2016 pp. 16

Conference poster

Comparative gene expression profiling of ADAMs, MMPs, TIMPs,EMMPRIN, EGF-R and VEGFA in low grade meningioma
Rooprai, H., Martin, A., King, A., Appadu, U., Jones, H., Selway, R., Gullan, R. and Pilkington, G. 2016. Comparative gene expression profiling of ADAMs, MMPs, TIMPs,EMMPRIN, EGF-R and VEGFA in low grade meningioma. International Journal of Oncology. 49 (6), pp. 2309-2318. https://doi.org/10.3892/ijo.2016.3739

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Inhibition of HIV virus by neutralizing Vhh attached to dual functional liposomes encapsulating dapivirine
Wang, S., Michiels, J., Ariën, K., New, R., Vanham, G. and Roitt, I. 2016. Inhibition of HIV virus by neutralizing Vhh attached to dual functional liposomes encapsulating dapivirine. Nanoscale Research Letters. 11 (1), pp. 1-10. https://doi.org/10.1186/s11671-016-1558-7

Article

Clinical characteristics and survival outcomes in BRCA1-methylated epithelial ovarian cancer (Bmeth-OC): A pooled analysis of data for 1,278 patients across five studies
2015. Clinical characteristics and survival outcomes in BRCA1-methylated epithelial ovarian cancer (Bmeth-OC): A pooled analysis of data for 1,278 patients across five studies. 2015 ASCO Annual Meeting. Chicago 29 May - 02 Jun 2015 pp. 5526-5526 https://doi.org/10.1200/jco.2015.33.15_suppl.5526

Conference poster

Can you spot the difference? Analysis of human chorionic gonadotropin (hCG) secreted by common non-trophoblastic and trophoblastic cancers
Gondek, M., Hills, F. and Burczynska, B. 2015. Can you spot the difference? Analysis of human chorionic gonadotropin (hCG) secreted by common non-trophoblastic and trophoblastic cancers. 2015 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 17 - 18 Jun 2015 Middlesex University.

Conference poster

Solution-processed anthracene-based molecular glasses as stable blue-light-emission laser gain media
Niu, Q., Zhang, Q., Xu, W., Jiang, Y., Xia, R., Bradley, D., Li, D. and Wen, S. 2015. Solution-processed anthracene-based molecular glasses as stable blue-light-emission laser gain media. Organic Electronics. 18, pp. 95-100. https://doi.org/10.1016/j.orgel.2015.01.012

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Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines
Busschots, S., O'Toole, S., O'Leary, J. and Stordal, B. 2015. Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines. MethodsX. 2, pp. 8-13. https://doi.org/10.1016/j.mex.2014.11.002

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Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer
McEvoy, L., O'Toole, S., Spillane, C., Martin, C., Gallagher, M., Stordal, B., Blackshields, G., Sheils, O. and O'Leary, J. 2015. Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer. BMC cancer. 15 (1). https://doi.org/10.1186/s12885-015-1539-8

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Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells
Busschots, S., O'Toole, S., O'Leary, J. and Stordal, B. 2015. Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells. Experimental Cell Research. 336 (1), pp. 1-14. https://doi.org/10.1016/j.yexcr.2014.12.001

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The role of vitamin In type 2 diabetes
Ali, A., Appiah, S., Shah, A. and Ghali, L. 2014. The role of vitamin In type 2 diabetes. 2014 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 19 Jun 2014

Conference poster

Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines
Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2014. Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines. 2014 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 19 Jun 2014

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Impact of inulin on bile acids induced colon cancer
Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2013. Impact of inulin on bile acids induced colon cancer. Third AACR International Conference on Frontiers in Basic Cancer Research. National Harbor, MD, United States 18 - 22 Sep 2013

Conference poster

Macrophage derived platelet activating factor implicated in the resolution phase of gouty inflammation
Yagnik, D. 2014. Macrophage derived platelet activating factor implicated in the resolution phase of gouty inflammation. International Journal of Inflammation. 2014, pp. 1-6. https://doi.org/10.1155/2014/526496

Article

The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer
D’Adhemar, C., Spillane, C., Gallagher, M., Bates, M., Costello, K., Barry-O'Crowley, J., Haley, K., Kernan, N., Murphy, C., Smyth, P., O'Byrne, K., Pennington, S., Cooke, A., Ffrench, B., Martin, C., O'Donnell, D., Hennessy, B., Stordal, B., Finn, S., McCann, A., Gleeson, N., D'Arcy, T., Flood, B., O'Neill, L., Sheils, O., O'Toole, S. and O'Leary, J. 2014. The MyD88+ phenotype is an adverse prognostic factor in epithelial ovarian cancer. PLoS ONE. 9 (6), pp. 1-15. https://doi.org/10.1371/journal.pone.0100816

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