Natural Sciences


TitleNatural Sciences
AlternativeS&T - NS
FacultyFaculty of Science and Technology

Latest research outputs

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Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast
Elayat, G., Selim, A. and Wells, C. 2009. Alterations of the cell cycle regulators cyclin D1, cyclin A, p27, p21, p16, and pRb in apocrine metaplasia of the breast. Breast Journal. 15 (5), pp. 475-482. https://doi.org/10.1111/j.1524-4741.2009.00762.x

Article

Laser modulation of angiogenic factor production by T-lymphocytes.
Agaiby, A., Ghali, L., Wilson, R. and Dyson, M. 2000. Laser modulation of angiogenic factor production by T-lymphocytes. Lasers in surgery and medicine. 26 (4), pp. 357-363. https://doi.org/10.1002/(SICI)1096-9101(2000)26:4<357::AID-LSM3>3.0.CO;2-O

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An association between sebaceous carcinoma and microsatellite instability in immunosuppressed organ transplant recipients
Harwood, C., Swale, V., Bataille, V., Quinn, A., Ghali, L., Patel, S., Dove-Edwin, I., Cerio, R. and McGregor, J. 2001. An association between sebaceous carcinoma and microsatellite instability in immunosuppressed organ transplant recipients. Journal of investigative dermatology. 116 (2), pp. 246-253. https://doi.org/10.1046/j.1523-1747.2001.01233.x

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Human β defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions
Chronnell, C., Ghali, L., Ali, R., Quinn, A., Holland, D., Bull, J., Cunliffe, W., McKay, I., Philpott, M. and Müller-Röver, S. 2001. Human β defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions. Journal of investigative dermatology. 117 (5), pp. 1120-1125. https://doi.org/10.1046/j.0022-202x.2001.01569.x

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Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus
Jackson, S., Ghali, L., Harwood, C. and Storey, A. 2002. Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus. British journal of cancer. 87 (3), pp. 319-323. https://doi.org/10.1038/sj.bjc.6600431

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Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization
Bloor, B., Tidman, N., Leigh, I., Odell, E., Dogan, B., Wollina, U., Ghali, L. and Waseem, A. 2003. Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization. American Journal of Pathology. 162 (3), pp. 963-975.

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The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin
Akgul, B., Garcia-Escudero, R., Ghali, L., Pfister, H., Fuchs, P., Navsaria, H. and Storey, A. 2005. The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin. Cancer Research. 65 (6), pp. 2216-2223. https://doi.org/10.1158/0008-5472.CAN-04-1952

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LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome.
Ong, C., O'Toole, E., Ghali, L., Malone, M., Smith, V., Callard, R. and Harper, J. 2004. LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome. British journal of dermatology. 151 (6), pp. 1253-1257. https://doi.org/10.1111/j.1365-2133.2004.06180.x

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Safety and efficacy of 5% imiquimod cream for the treatment of skin dysplasia in high-risk renal transplant recipients: randomized, double-blind, placebo-controlled trial
Brown, V., Atkins, C., Ghali, L., Cerio, R., Harwood, C. and Proby, C. 2005. Safety and efficacy of 5% imiquimod cream for the treatment of skin dysplasia in high-risk renal transplant recipients: randomized, double-blind, placebo-controlled trial. Archives of Dermatology. 141 (8), pp. 985-993.

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Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours
Green, J., Ikram, M., Vyas, J., Patel, N., Proby, C., Ghali, L., Leigh, I., O'Toole, E. and Storey, A. 2006. Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours. British journal of cancer. 94 (10), pp. 1446-1451.

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Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria.
Leverrier, S., Bergamaschi, D., Ghali, L., Ola, A., Warnes, G., Akgul, B., Blight, K., Garcia-Escudero, R., Penna, A., Eddaoudi, A. and Storey, A. 2007. Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria. Apoptosis: an international journal on programmed cell death. 12 (3), pp. 549-560. https://doi.org/10.1007/s10495-006-0004-1

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Role for WNT16B in human epidermal keratinocyte proliferation and differentiation
Teh, M., Blaydon, D., Ghali, L., Briggs, V., Edmunds, S., Pantazi, E., Barnes, M., Leigh, I., Kelsell, D. and Philpott, M. 2007. Role for WNT16B in human epidermal keratinocyte proliferation and differentiation. Journal of Cell Science. 120 (2), pp. 330-339.

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Longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of NOS1 and elastin in uncomplicated diverticular disease.
Golder, M., Burleigh, D., Ghali, L., Feakins, R., Lunniss, P., Williams, N. and Navsaria, H. 2007. Longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of NOS1 and elastin in uncomplicated diverticular disease. Colorectal disease. 9 (3), pp. 218-228.

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HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes.
Akgul, B., Ghali, L., Davies, D., Pfister, H., Leigh, I. and Storey, A. 2007. HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes. Clinical and experimental dermatology. 16 (7), pp. 590-599.

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Granulosa cell survival and proliferation are altered in polycystic ovary syndrome
Das, M., Djahanbakhch, O., Hacihanefioglu, B., Saridogan, E., Ikram, M., Ghali, L., Raveendran, M. and Storey, A. 2008. Granulosa cell survival and proliferation are altered in polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism. 93 (3), pp. 881-887. https://doi.org/10.1210/jc.2007-1650

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GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes
Neill, G., Harrison, W., Ikram, M., Williams, T., Bianchi, L., Nadenla, S., Green, J., Ghali, L., Frischauf, A., O'Toole, E., Aberger, F. and Philpott, M. 2008. GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes. Carcinogenesis. 29 (4), pp. 738-746. https://doi.org/10.1093/carcin/bgn037

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A low budget luminometer for sensitive chemiluminescent immunoassays
Porakishvili, N., Fordham, J., Charrel-Dennis, M., Delves, P., Lund, T. and Roitt, I. 2000. A low budget luminometer for sensitive chemiluminescent immunoassays. Journal of Immunological Methods. 234 (1-2), pp. 35-42. https://doi.org/10.1016/S0022-1759(99)00198-2

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The immune system: second of two parts
Delves, P. and Roitt, I. 2000. The immune system: second of two parts. New England Journal of Medicine. 343 (2), pp. 108-117.

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The immune system: first of two parts
Delves, P. and Roitt, I. 2000. The immune system: first of two parts. New England Journal of Medicine. 343 (1), pp. 37-49.

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Future prospects for vaccines to control fertility
Delves, P., Lund, T. and Roitt, I. 2002. Future prospects for vaccines to control fertility. Trends in Immunology. 23 (4), pp. 220-221. https://doi.org/10.1016/S1471-4906(02)02183-X

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Antifertility vaccines
Delves, P., Lund, T. and Roitt, I. 2002. Antifertility vaccines. Trends in Immunology. 23 (4), pp. 213-219. https://doi.org/10.1016/S1471-4906(02)02182-8

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Vaccines for the control of reproduction - status in mammals, and aspects of comparative interest.
Delves, P. and Roitt, I. 2005. Vaccines for the control of reproduction - status in mammals, and aspects of comparative interest. Developments in Biologicals. 121, pp. 265-273.

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A longitudinal study of maternal plasma insulin-like growth factor binding protein-1 concentrations during normal pregnancy and pregnancies complicated by pre-eclampsia
Anim-Nyame, N., Hills, F., Soorana, S., Steer, P. and Johnson, M. 2000. A longitudinal study of maternal plasma insulin-like growth factor binding protein-1 concentrations during normal pregnancy and pregnancies complicated by pre-eclampsia. Human Reproduction. 15 (10), pp. 2215-2219. https://doi.org/10.1093/humrep/15.10.2215

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Interactions between progesterone receptor isoforms in myometrial cells in human labour
Pieber, D., Allport, V., Hills, F., Johnson, M. and Bennett, P. 2001. Interactions between progesterone receptor isoforms in myometrial cells in human labour. Molecular Human Reproduction. 7 (9), pp. 875-879. https://doi.org/10.1093/molehr/7.9.875

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Regulated expression of signal transducer and activator of transcription, Stat5, and its enhancement of PRL expression in human endometrial stromal cells in vitro
Mak, I., Brosens, J., Christian, M., Hills, F., Chamley, L., Regan, L. and White, J. 2002. Regulated expression of signal transducer and activator of transcription, Stat5, and its enhancement of PRL expression in human endometrial stromal cells in vitro. Journal of Clinical Endocrinology and Metabolism. 87 (6), pp. 2581-2588. https://doi.org/10.1210/jc.87.6.2581

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Progesterone represses interleukin-8 and cyclo-oxygenase-2 in human lower segment fibroblast cells and amnion epithelial cells
Loudon, J., Elliott, C., Hills, F. and Bennett, P. 2003. Progesterone represses interleukin-8 and cyclo-oxygenase-2 in human lower segment fibroblast cells and amnion epithelial cells. Biology of Reproduction. 69 (1), pp. 331-337.

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The relationship between insulin and insulin-like growth factor binding protein-1 is modified by pre-eclampsia.
Anim-Nyame, N., Hills, F., Soorana, S., Steer, P. and Johnson, M. 2003. The relationship between insulin and insulin-like growth factor binding protein-1 is modified by pre-eclampsia. Gynecological endocrinology.. 17 (6), pp. 471-476. https://doi.org/10.1080/09513590312331290408

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The insulin-like growth factor system in mammalian pregnancy: a workshop report
Carter, A., Hills, F., O'Gorman, D., Robets, C., Soorana, S., Watson, C. and Westwood, M. 2004. The insulin-like growth factor system in mammalian pregnancy: a workshop report. Placenta. 25 (Supple), pp. S53-S56. https://doi.org/10.1016/j.placenta.2004.01.019

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Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human
Monk, D., Sanches, R., Arnaud, P., Apostolidou, S., Hills, F., Abu-Amero, S., Murrell, A., Friess, H., Reik, W. and Stanier, P. 2006. Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human. Human Molecular Genetics. 15 (8), pp. 1259-1269. https://doi.org/10.1093/hmg/ddl041

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Monocyte Fc gamma receptor expression in patients undergoing coronary artery bypass grafting
Stefanou, D., Asimakopoulos, G., Yagnik, D., Haskard, D., Anderson, J., Philippidis, P., Landis, R. and Taylor, K. 2004. Monocyte Fc gamma receptor expression in patients undergoing coronary artery bypass grafting. Annals of Thoracic Surgery. 77 (3), pp. 951-955.

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Two-dimensional finite element modelling of the neonatal head
Gibson, A., Bayford, R. and Holder, D. 2000. Two-dimensional finite element modelling of the neonatal head. Physiological Measurement. 21 (1), pp. 45-52. https://doi.org/10.1088/0967-3334/21/1/306

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Validation of a 3D reconstruction algorithm for EIT of human brain function in a realistic head-shaped tank
Tidswell, A., Gibson, A., Bayford, R. and Holder, D. 2001. Validation of a 3D reconstruction algorithm for EIT of human brain function in a realistic head-shaped tank. Physiological Measurement. 22 (1), pp. 177-185. https://doi.org/10.1088/0967-3334/22/1/321

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Electrical impedance tomography of human brain activity with a two-dimensional ring of scalp electrodes
Tidswell, A., Gibson, A., Bayford, R. and Holder, D. 2001. Electrical impedance tomography of human brain activity with a two-dimensional ring of scalp electrodes. Physiological Measurement. 22 (1), pp. 167-175. https://doi.org/10.1088/0967-3334/22/1/320

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A feasibility study of remote monitoring of asthmatic patients.
Steel, S., Lock, S., Johnson, N., Martinez, Y., Marquilles, E. and Bayford, R. 2002. A feasibility study of remote monitoring of asthmatic patients. Journal of telemedicine and telecare. 8 (5), pp. 290-296.

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Design and performance of the UCLH mark 1b 64 channel electrical impedance tomography (EIT) system, optimized for imaging brain function
Yerworth, R., Bayford, R., Cusick, G., Conway, M. and Holder, D. 2002. Design and performance of the UCLH mark 1b 64 channel electrical impedance tomography (EIT) system, optimized for imaging brain function. Physiological Measurement. 23 (1), pp. 149-158. https://doi.org/10.1088/0967-3334/23/1/314

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A multi-shell algorithm to reconstruct EIT images of brain function
Liston, A., Bayford, R., Tidswell, A. and Holder, D. 2002. A multi-shell algorithm to reconstruct EIT images of brain function. Physiological Measurement. 23 (1), pp. 105-119. https://doi.org/10.1088/0967-3334/23/1/310

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A comparison of headnet electrode arrays for electrical impedance tomography of the human head
Tidswell, A., Bagshaw, A., Holder, D., Yerworth, R., Eadie, L., Murray, S., Morgan, L. and Bayford, R. 2003. A comparison of headnet electrode arrays for electrical impedance tomography of the human head. Physiological Measurement. 24 (2), pp. 527-544. https://doi.org/10.1088/0967-3334/24/2/363

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Electrical impedance tomography spectroscopy (EITS) for human head imaging
Yerworth, R., Bayford, R., Brown, B., Milnes, P., Conway, M. and Holder, D. 2003. Electrical impedance tomography spectroscopy (EITS) for human head imaging. Physiological Measurement. 24 (2), pp. 477-489. https://doi.org/10.1088/0967-3334/24/2/358

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The application of the generalized vector sample pattern matching method for EIT image reconstruction
Dong, G., Bayford, R., Gao, S., Saito, Y., Yerworth, R., Holder, D. and Yan, W. 2003. The application of the generalized vector sample pattern matching method for EIT image reconstruction. Physiological Measurement. 24 (2), pp. 449-466. https://doi.org/10.1088/0967-3334/24/2/356

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Neuromagnetic field strength outside the human head due to impedance changes from neuronal depolarization
Ahadzi, G., Liston, A., Bayford, R. and Holder, D. 2004. Neuromagnetic field strength outside the human head due to impedance changes from neuronal depolarization. Physiological Measurement. 25 (1), pp. 365-378. https://doi.org/10.1088/0967-3334/25/1/040

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