A randomized controlled trial comparison of three music therapy formats on cognitive function and psychological well-being in normal aging

Article


Mangiacotti, A., Ward, E.V., Williams, S., Barone, C., Ataye, K., Asue, M.L., Behram, A., Hsu, M.H., Lovato, E., Zandona, A. and Franco, F. 2026. A randomized controlled trial comparison of three music therapy formats on cognitive function and psychological well-being in normal aging. The Journals of Gerontology, Series B: Psychological Sciences and Social Sciences . 81 (6). https://doi.org/10.1093/geronb/gbag070
TypeArticle
TitleA randomized controlled trial comparison of three music therapy formats on cognitive function and psychological well-being in normal aging
AuthorsMangiacotti, A., Ward, E.V., Williams, S., Barone, C., Ataye, K., Asue, M.L., Behram, A., Hsu, M.H., Lovato, E., Zandona, A. and Franco, F.
Abstract

Objectives: Prior studies suggest a benefit of music-based activities for supporting cognitive function and psychological wellbeing in normal aging, but few have rigorously examined the effect of music therapy (MT) interventions in this population, or contrasted delivery format. We conducted a randomized controlled trial study investigating the effects of one-to-one, small-group, and large-group MT on cognitive functions and wellbeing in 62 older adults without cognitive impairment.
Methods: Participants were randomly assigned to one-to-one (M age=79.71), small-group (M age=82.00), or large-group (M age=79.83) conditions, and received structured MT sessions over 20-weeks, while a passive control group (M age=74.56) received no MT. Pre-post intervention measures assessed cognitive functions (memory, attention, executive function, verbal fluency) and wellbeing (general wellbeing, depression, sleep quality).
Results: Mixed ANOVAs indicated improvements pre-post intervention on several cognitive measures and depressive symptoms (main effects of Time) that varied as a function of MT format (Time x Group interactions). All MT groups showed improvements in cognitive functions pre-post intervention, while many cognitive scores declined in the control group. Further, all intervention groups showed a significant reduction in depressive symptoms pre-post intervention, while there was no change in the control group. Dynamic Bayesian Network analysis corroborated these trajectories and highlighted the influence of cognitive reserve and executive functions on intervention outcomes.
Discussion: This study provides evidence for the beneficial effect of MT on cognitive function and wellbeing in normal aging, suggesting that both individualised and group formats are advantageous. This has implications for supporting healthy aging through socially prescribed standardised protocols.

Keywordscognitive decline; healthy aging; music interventions; randomized controlled trial; social prescribing
Sustainable Development Goals3 Good health and well-being
Middlesex University ThemeHealth & Wellbeing
Research GroupCognitive Psychology and Neuroscience Research Group
PublisherOxford University Press (OUP)
JournalThe Journals of Gerontology, Series B: Psychological Sciences and Social Sciences
ISSN1079-5014
Electronic1758-5368
Publication dates
Online21 May 2026
PrintJun 2026
Publication process dates
Submitted26 Aug 2025
Accepted11 Mar 2026
Deposited14 Apr 2026
Output statusPublished
Accepted author manuscript
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Open
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Copyright Statement

For the purpose of open access, the author has applied a Creative Commons Attribution (CC BY) licence to any Author Accepted Manuscript version of this paper, arising from this submission.

Digital Object Identifier (DOI)https://doi.org/10.1093/geronb/gbag070
PubMed ID42161569
LanguageEnglish
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