Natural Sciences
| Title | Natural Sciences |
|---|---|
| Alternative | S&T - NS |
| Faculty | Faculty of Science and Technology |
Latest research outputs
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Structure-related cytotoxic effects of flavones and doxorubicin in chronic myeloid leukaemia and non-cancerous cells in vitro– a preliminary study [Abstract]
Punev, I., Vu, M., Devo, P., Shi, Z. and Appiah, S. 2025. Structure-related cytotoxic effects of flavones and doxorubicin in chronic myeloid leukaemia and non-cancerous cells in vitro– a preliminary study [Abstract]. International Conference on African Development. Aston University, Birmingham 18 - 20 Jun 2025 Ghana Scholarly Society. pp. 101-101Conference item
Label-free electrochemical detection of transthyretin for patients with cardiac amyloidosis
Sekhon, S., Verona, G., Bayford, R. and Demosthenous, A. 2025. Label-free electrochemical detection of transthyretin for patients with cardiac amyloidosis. IEEE SENSORS 2025. Vancouver, BC, Canada 19 - 22 Oct 2025 IEEE. https://doi.org/10.1109/sensors59705.2025.11330334Conference paper
Bioimpedance-driven haptic feedback for human-computer interaction
Yao, T., Bayford, R. and Demosthenous, A. 2025. Bioimpedance-driven haptic feedback for human-computer interaction. IEEE SENSORS 2025. Vancouver, BC, Canada 19 - 22 Oct 2025 IEEE. https://doi.org/10.1109/sensors59705.2025.11330338Conference paper
Histological assessment of inflammatory infiltrates in interstitial cystitis/bladder pain syndrome (IC/BPS): a comparative study of mast cell quantification techniques [Abstract]
Akmandor, T. and Freeman, A. 2025. Histological assessment of inflammatory infiltrates in interstitial cystitis/bladder pain syndrome (IC/BPS): a comparative study of mast cell quantification techniques [Abstract]. Medicine 2025: The Future of Medicine. RCP Annual Conference. London, UK 02 - 03 Jun 2025 Elsevier. https://doi.org/10.1016/j.clinme.2025.100405Conference item
316eP Imiquimod-loaded dissolvable microneedles: a novel pre-clinical immunotherapeutic approach for dermato-oncology
Akmandor, T., Russo, C., Loizidou, E., Leontiev, D. and Hyseni, A. 2025. 316eP Imiquimod-loaded dissolvable microneedles: a novel pre-clinical immunotherapeutic approach for dermato-oncology. ESMO Immuno-Oncology Congress 2025. London, UK 10 - 12 Dec 2025 Elsevier. https://doi.org/10.1016/j.iotech.2025.101515Conference poster
315eP Pre-clinical feasibility and translational challenges of cytokine-loaded dissolvable microneedles for cutaneous immunotherapy
Akmandor, T., Outram, S., Russo, C. and Loizidou, E. 2025. 315eP Pre-clinical feasibility and translational challenges of cytokine-loaded dissolvable microneedles for cutaneous immunotherapy. ESMO Immuno-Oncology Congress 2025. London, UK 10 - 12 Dec 2025 Elsevier. https://doi.org/10.1016/j.iotech.2025.101514Conference poster
Advances in U-Net and image processing: a path to early cancer diagnosis
Alpan, K., Rahman, S., Wen, X. and Dirilenoglu, F. 2025. Advances in U-Net and image processing: a path to early cancer diagnosis. 9th International Symposium on Multidisciplinary Studies and Innovative Technologies. Ankara, Turkey 14 - 16 Nov 2025 IEEE. pp. 1-6 https://doi.org/10.1109/ismsit67332.2025.11267924Conference paper
The therapeutic effect of EZH2 inhibitors in targeting human papillomavirus associated cervical cancer
Vidalina, D., Ghali, L., Kassouf, N., Li, S., Li, D. and Wen, X. 2025. The therapeutic effect of EZH2 inhibitors in targeting human papillomavirus associated cervical cancer. Current Issues in Molecular Biology. 47 (12), p. 990. https://doi.org/10.3390/cimb47120990Article
Comparative assessment of ChatGPT, DeepSeek, and human reviewers for full-text screening in systematic reviews on the impact of air pollution in respiratory diseases
Manullang, A., Gao, X., Viavattene, C. and Rahmanti, A.R. 2025. Comparative assessment of ChatGPT, DeepSeek, and human reviewers for full-text screening in systematic reviews on the impact of air pollution in respiratory diseases. Bramer, M. and Stahl, F. (ed.) 45th SGAI International Conference on Artificial Intelligence. Cambridge, UK 16 - 18 Dec 2025 Springer. pp. 478-484 https://doi.org/10.1007/978-3-032-11442-6_39Conference paper
Diagnosing thrombophilia: the case for genetic or functional testing?
Favaloro, E.J., Moore, G.W. and Pasalic, L. 2025. Diagnosing thrombophilia: the case for genetic or functional testing? Expert Review of Molecular Diagnostics. 25 (12), pp. 841-846. https://doi.org/10.1080/14737159.2025.2588621Article
Survey on current practice in thrombophilia testing: from phenotype to genotype. Communication from the SSC of the ISTH
Van Laer, C., Moore, G.W., Majumder, R., Corral, J., Freson, K., Ignjatovic, V. and Orlando, C. 2025. Survey on current practice in thrombophilia testing: from phenotype to genotype. Communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis. https://doi.org/10.1016/j.jtha.2025.10.032Article
Changes in lung volume and ventilation during apnoea of prematurity using EIT
Miedema, M., Yerworth, R., Waldmann, A.D., Frerichs, I., Bayford, R. and Van Kaam, A.H. 2025. Changes in lung volume and ventilation during apnoea of prematurity using EIT. Pediatric Pulmonology. 60 (11). https://doi.org/10.1002/ppul.71369Article
A series of acute psychological priming interventions assessing changes in hormonal and physical performance measures during resistance training
Collins, J., Bishop, C., Spiegelhalter, A., Wilson, L., Hills, F. and Turner, A. 2025. A series of acute psychological priming interventions assessing changes in hormonal and physical performance measures during resistance training. Applied Sciences. 15 (21). https://doi.org/10.3390/app152111538Article
Next generation developments in electrical impedance tomography (EIT)
Bayford, R., Sadleir, R., Frerichs, I. and Zhao, Z. 2025. Next generation developments in electrical impedance tomography (EIT). Physiological Measurement. 46 (10). https://doi.org/10.1088/1361-6579/ae0dedArticle
Design, synthesis, and biological evaluation of efflux-resistant imatinib derivatives
Chowdhury, M.M., Pretheshan, P., Chowdhury, N.S., Andriollo, P., Shah, A.J., Forbes, B., Pepper, C. and Rahman, K.M. 2025. Design, synthesis, and biological evaluation of efflux-resistant imatinib derivatives. Journal of Medicinal Chemistry. 68 (21), pp. 22619-22632. https://doi.org/10.1021/acs.jmedchem.5c01596Article
Integrated cellular, proteomic and metabolite analysis of argyrin B with rational design approaches for immunoproteasome-selective inhibitors
Allardyce, D.J. 2025. Integrated cellular, proteomic and metabolite analysis of argyrin B with rational design approaches for immunoproteasome-selective inhibitors. PhD thesis Middlesex UniversityPhD thesis
Efflux resistance breakers: a new technology to overcome efflux-mediated resistance in multidrug resistant bacteria
Laws, M., Hind, C., Nahar, K., Clifford, M., Marsh, C., Xu, M., Alyemni, S., Haider, S., Hassan, M., Gargate, N., Wand, M., Sutton, M. and Rahman, K.M. 2025. Efflux resistance breakers: a new technology to overcome efflux-mediated resistance in multidrug resistant bacteria. https://doi.org/10.26434/chemrxiv-2025-gsw00Pre-print
Mixed method analysis of household recycling challenges and the development of a sustainable recycling indicator
Oluwadipe, S, Purchase, D., Garelick, H., McCarthy, S. and Jones, H. 2025. Mixed method analysis of household recycling challenges and the development of a sustainable recycling indicator. Waste Management. 208. https://doi.org/10.1016/j.wasman.2025.115170Article
Convergent evolution of antibiotic resistance mechanisms between pyrrolobenzodiazepines and albicidin in multidrug resistant Klebsiella pneumoniae
Surani, Y.M., Wand, M.E., Picconi, P., Di Palma, M., Zenezini Chiozzi, R., Hasan, Md. M., Andriollo, P., Grätz, S., Nahar, K., Maynard-Smith, M., Süssmuth, R.D., Steiner, R.A., Rahman, K.M., Hind, C.K and Sutton, J. M. 2025. Convergent evolution of antibiotic resistance mechanisms between pyrrolobenzodiazepines and albicidin in multidrug resistant Klebsiella pneumoniae. npj Antimicrobials and Resistance . 3 (1). https://doi.org/10.1038/s44259-025-00104-4Article
Novltex: a new class of antibiotics with potent activity against multidrug-resistant bacterial pathogens - design, synthesis, and biological evaluation
Malkawi, E., Parmar, A., Das, S., Newire, E., Jones, C.M., Morrison, K.A., Karak, M., Blanc, F., Harper, N., Lakshminarayanan, R., Poh, Z.S., Verma, N.K., Unsworth, J., Hughes, D.E., Ling, L.L., Cochrane, S.A., Hope, W. and Singh, I. 2025. Novltex: a new class of antibiotics with potent activity against multidrug-resistant bacterial pathogens - design, synthesis, and biological evaluation. Journal of Medicinal Chemistry. https://doi.org/10.1021/acs.jmedchem.5c01193Article
Spatiotemporal disparity of breast cancer incidence in Iranian female populations at the district level from 2000 to 2021: Bayesian disease mapping
Rahimzadeh, S., Bentham, J., Burczynska, B., Farzadfar, F. and Di Cesare, M. 2025. Spatiotemporal disparity of breast cancer incidence in Iranian female populations at the district level from 2000 to 2021: Bayesian disease mapping. PLoS ONE. 20 (9). https://doi.org/10.1371/journal.pone.0330017Article
Biosurfactant-mediated inhibition of Salmonella typhimurium biofilms on plastics: influence of lipopolysaccharide structure
Khonsari, S., Cossu, A., Vu, M., Roulston, D., Marvasi, M. and Purchase, D. 2025. Biosurfactant-mediated inhibition of Salmonella typhimurium biofilms on plastics: influence of lipopolysaccharide structure. Microorganism. 13 (9). https://doi.org/10.3390/microorganisms13092130Article
Enabling community maintenance for local flood risk management: briefing note for policy and strategy staff: enabling and supporting communities in voluntary maintenance of flood assets (C821c)
Twigger-Ross, C., Simm, J. and McCarthy, S. 2025. Enabling community maintenance for local flood risk management: briefing note for policy and strategy staff: enabling and supporting communities in voluntary maintenance of flood assets (C821c). London, UK Construction Industry Research and Information Association (CIRIA).Report
Enabling community maintenance for local flood risk management: risk management authorities' guide to supporting community maintenance (C821b) [Monograph - Other]
Simm, J., Twigger-Ross, C., McCarthy, S., Berwick, N., Woods Ballard, B., Esposito, A., Sheperd, H. and Garrett, T. 2025. Enabling community maintenance for local flood risk management: risk management authorities' guide to supporting community maintenance (C821b) [Monograph - Other]. London, UK Construction Industry Research and Information Association (CIRIA).Report
Taking action: reducing the risk of flooding for your community by maintaining drainage, watercourses and flood defences (C821a)
Simm, J., Twigger-Ross, C., McCarthy, S., Berwick, N., Woods Ballard, B., Esposito, A., Shepherd, H. and Garrett, T. 2025. Taking action: reducing the risk of flooding for your community by maintaining drainage, watercourses and flood defences (C821a). London, UK Construction Industry Research and Information Association (CIRIA).Report
Unlocking the metabolic potential of endophytic fungi through epigenetics: a paradigm shift for natural product discovery and plant-microbe interactions
Liu, R, Peng, X-P, Newman, D.J., Purchase, D., Li, G. and Kusari, S. 2025. Unlocking the metabolic potential of endophytic fungi through epigenetics: a paradigm shift for natural product discovery and plant-microbe interactions. Natural Product Reports. https://doi.org/10.1039/D5NP00028AArticle
Capacitive sensors for label-free detection in high-ionic-strength bodily fluids: a review
Sekhon, S., Bayford, R. and Demosthenous, A. 2025. Capacitive sensors for label-free detection in high-ionic-strength bodily fluids: a review. Biosensors. 15 (8). https://doi.org/10.3390/bios15080491Article
Annona muricata Graviola induces apoptosis in two osteosarcoma cell lines and downregulates the cytokines IL-6 and TGFβ1 which are implicated in tumour growth and metastasis
Yagnik, D., Neergheen, V., Grant, C. and Shah, A. 2025. Annona muricata Graviola induces apoptosis in two osteosarcoma cell lines and downregulates the cytokines IL-6 and TGFβ1 which are implicated in tumour growth and metastasis. Integrative Cancer Therapies. 24. https://doi.org/10.1177/15347354251360338Article
Beyond the type 1 pattern: comprehensive risk stratification in Brugada Syndrome
Kan, K.Y., Van Wyk, A., Paterson, T., Ninan, N., Lysyganicz, P., Tyagi, I., Lizi, R.B., Boukrid, F., Alfaifi, M., Mishra, A., Katraj, S.V.K. and Pooranachandran, V. 2025. Beyond the type 1 pattern: comprehensive risk stratification in Brugada Syndrome. Journal of Interventional Cardiac Electrophysiology. 68 (8), pp. 1771-1790. https://doi.org/10.1007/s10840-025-02101-zArticle
Critical insights on fungal contamination in schools: a comprehensive review of assessment methods
Cervantes, R., Pena, P., Riesenberger, B., Rodriguez, M., Henderson, D., Gonçalves, S., Newire, E., Pogner, C., Salonen, H., Silva, M.A., Ferguson. R.M.W., Haverinen-Shaughnessy, U. and Viegas, C. 2025. Critical insights on fungal contamination in schools: a comprehensive review of assessment methods. Frontiers in Public Health. 13. https://doi.org/10.3389/fpubh.2025.1557506Article
Identifying social vulnerability profiles for coastal flood using supervised and unsupervised machine learning: a case study of Lekki peninsula, Lagos, Nigeria
Akindejoye, A., Viavattene, C., Priest, S. and Windridge, D. 2025. Identifying social vulnerability profiles for coastal flood using supervised and unsupervised machine learning: a case study of Lekki peninsula, Lagos, Nigeria. International Journal of Disaster Risk Reduction. 127. https://doi.org/10.1016/j.ijdrr.2025.105693Article
Detecting apnoea in premature neonates: exploring frequency-domain and power analysis of electrical impedance tomography lung impedance signals
Omisanya, J., Wen, X., Yerworth, R., Meidema, M., Kaam, A., Demosthenous, A. and Bayford, R. 2025. Detecting apnoea in premature neonates: exploring frequency-domain and power analysis of electrical impedance tomography lung impedance signals. Journal of Physics: Conference Series. 3014 (1). https://doi.org/10.1088/1742-6596/3014/1/012016Article
Assessing the validity of the LEAF-Q and FAST questionnaires for detecting low energy availability in competitive female netball players
Watson, K., Spiegelhalter, A., Curtis, C., Papadopoulos, K., Hills, F., Turner, A. and Wilson, L. 2025. Assessing the validity of the LEAF-Q and FAST questionnaires for detecting low energy availability in competitive female netball players. 2025 Middlesex University Postgraduate Researchers Summer Conference. Middlesex University London, UK 17 - 18 Jun 2025Conference poster
New generation modified azole antifungals against multidrug-resistant Candida auris
Chen, Y., Li, Y., Nahar, K., Hasan, Md. M., Marsh, C., Clifford, M., Aleku, G.A., Kelly, S.L., Lamb, D.C., Mpamhanga, C.D., Kounatidis, I., Shah, A., Hind, C.K., Sutton, J.M. and Rahman, K.M. 2025. New generation modified azole antifungals against multidrug-resistant Candida auris . Journal of Medicinal Chemistry. 68 (13), pp. 14054-14071. https://doi.org/10.1021/acs.jmedchem.5c01253Article
A single-stage differential amplifier using organic electrochemical transistors
Fahimi Hanzaee, F., Dimov, I.B., Gatecliff, L.W., Bayford, R., Malliaras, G.G., Demosthenous, A. and Donaldson, N. de N. 2025. A single-stage differential amplifier using organic electrochemical transistors. Advanced Electronic Materials. https://doi.org/10.1002/aelm.202400755Article
Genome wide analyses corroborate cryptic speciation in Anurida maritima (Collembola, Poduromorpha)
Timmermans, M. 2025. Genome wide analyses corroborate cryptic speciation in Anurida maritima (Collembola, Poduromorpha). Zoologica Scripta. 54 (5), pp. 649-657. https://doi.org/10.1111/zsc.12728Article
Changes in respiratory patterns from Pressure Control Ventilation to Neurally Adjusted Ventilatory Assist assessed by Electrical Impedance Tomography
Rathu, M., Frerichs, I., Becher, T.H., Pokka, T., Waldmann, A.D., Papadouri, T., van Kaam, A.H., Rimensberger, P.C., Bayford, R., Peltoniemi, O. and Kallio, M. 2025. Changes in respiratory patterns from Pressure Control Ventilation to Neurally Adjusted Ventilatory Assist assessed by Electrical Impedance Tomography. Pediatric Pulmonology. 60 (4). https://doi.org/10.1002/ppul.71077Article
Biodeterioration of cultural heritage monuments: a review of their deterioration mechanisms and conservation
Yadav, S. and Purchase, D. 2025. Biodeterioration of cultural heritage monuments: a review of their deterioration mechanisms and conservation. International Biodeterioration and Biodegradation. 201, p. 106066. https://doi.org/10.1016/j.ibiod.2025.106066Article
Forearm motion and hand grasp prediction based on target muscle bioimpedance for Human-Machine Interaction
Yao, T., Wu, Y., Jiang, D., Bayford, R. and Demosthenous, A. 2025. Forearm motion and hand grasp prediction based on target muscle bioimpedance for Human-Machine Interaction. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 33, pp. 760-769. https://doi.org/10.1109/TNSRE.2025.3538609Article
Understanding and managing iron deficiency anaemia
Papagiannaki, M. 2025. Understanding and managing iron deficiency anaemia. Nursing Standard. 40 (3), pp. 61-66. https://doi.org/10.7748/ns.2025.e12430Article
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