Natural Sciences
| Title | Natural Sciences |
|---|---|
| Alternative | S&T - NS |
| Faculty | Faculty of Science and Technology |
Latest research outputs
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Multi-objective optimization methods in de novo drug design
Nicolaou, C., Kannas, C. and Loizidou, E. 2012. Multi-objective optimization methods in de novo drug design. Mini Reviews in Medicinal Chemistry. 12 (10), pp. 979-987. https://doi.org/10.2174/138955712802762284Article
Structural assignment and total synthesis of azaspiracid-1
Frederick, M., Cole, K., Petrovic, G., Loizidou, E. and Nicolaou, K. 2007. Structural assignment and total synthesis of azaspiracid-1. in: Botana, L. (ed.) Phycotoxins: chemistry and biochemistry Ames, Iowa WileyBlackwell. pp. 297-309Book chapter
Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity
Loizidou, E. and Zeinalipour-Yazdi, C. 2014. Computational inhibition studies of the human proteasome by argyrin-based analogues with subunit specificity. Chemical Biology and Drug Design. 84 (1), pp. 99-107. https://doi.org/10.1111/cbdd.12298Article
Receptor-attached amphiphilic terpolymer for selective drug recognition in aqueous solutions
Loizidou, E., Sun, L. and Zeinalipour-Yazdi, C. 2011. Receptor-attached amphiphilic terpolymer for selective drug recognition in aqueous solutions. Journal of Molecular Recognition. 24 (4), pp. 678-686. https://doi.org/10.1002/jmr.1098Article
Analysis of binding parameters of HIV-1 integrase inhibitors: correlates of drug inhibition and resistance
Loizidou, E., Zeinalipour-Yazdi, C., Christofides, T. and Kostrikis, L. 2009. Analysis of binding parameters of HIV-1 integrase inhibitors: correlates of drug inhibition and resistance. Bioorganic & Medicinal Chemistry. 17 (13), pp. 4806-4818. https://doi.org/10.1016/j.bmc.2009.04.058Article
Second generation total synthesis of azaspiracids-1, -2 and -3
Nicolaou, K., Frederick, M., Loizidou, E., Petrovic, G., Cole, K., Koftis, T. and Yamada, Y. 2006. Second generation total synthesis of azaspiracids-1, -2 and -3. Chemistry: an Asian Journal. 1 (1-2), pp. 245-263. https://doi.org/10.1002/asia.200600059Article
A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes
Janganan T.K., Chen, G., Chen, D., Menino, J.F., Rodrigues, F., Borges-Walmsley, M.I. and Walmsley, A.R. 2015. A Gβ protein and the TupA co-regulator bind to protein kinase a Tpk2 to act as antagonistic molecular switches of fungal morphological changes. PLoS ONE. 10 (9). https://doi.org/10.1371/journal.pone.0136866Article
Association between early postoperatively elevated TLR-4 & TLR-5 gene expression and late nosocomial infection in elective high-risk hepato-pancreato-biliary (HPB) surgery
Pirmadjid, N., Torrance, H., Owen, H., Alazawi, W. and O'Dwyer, M. 2015. Association between early postoperatively elevated TLR-4 & TLR-5 gene expression and late nosocomial infection in elective high-risk hepato-pancreato-biliary (HPB) surgery. 2015 International Surgical Congress of the Association of Surgeons of Great Britain and Ireland. Manchester, UK 22 - 24 Apr 2015 Oxford University Press (OUP).Conference item
Prediction intervals for electric load forecast: evaluation for different profiles
Gomes de Almeida, V. and Gama, J. 2015. Prediction intervals for electric load forecast: evaluation for different profiles. 2015 18th International Conference on Intelligent System Application to Power Systems (ISAP). Porto, Portugal 11 - 16 Sep 2015 Institute of Electrical and Electronics Engineers (IEEE). pp. 1-6 https://doi.org/10.1109/ISAP.2015.7325539Conference paper
Signal (stream) synchronization with white noise sources, in biomedical applications
Vaz, P., Gomes de Almeida, V., Ferreira, L., Correia, C. and Cardoso, J. 2015. Signal (stream) synchronization with white noise sources, in biomedical applications. Biomedical Signal Processing and Control. 18, pp. 394-400. https://doi.org/10.1016/j.bspc.2015.02.015Article
The developing role of evidence-based environmental health: perceptions, experiences, and understandings from the front line
Dhesi, S. and Stewart, J. 2015. The developing role of evidence-based environmental health: perceptions, experiences, and understandings from the front line. SAGE Open. 5 (4), pp. 1-10. https://doi.org/10.1177/2158244015611711Article
The developing role of evidence based environmental health: perceptions, experiences and understandings from the front line
Dhesi, S. and Stewart, J. 2015. The developing role of evidence based environmental health: perceptions, experiences and understandings from the front line. SAGE Open. 5 (4). https://doi.org/10.1177/2158244015611711Article
Running to keep up: a research journey
Plume, R., Page, A. and Garelick, H. 2015. Running to keep up: a research journey. CIEH/Middlesex University: Research practice Conference: Bridging Policy and Practice with Research. Middlesex University, London, United Kingdom 12 Nov 2015Conference item
Evolving models of environmental health service delivery: a real-time experiment?
Plume, R. and Page, A. 2015. Evolving models of environmental health service delivery: a real-time experiment? Chartered Institute of Environmental Health: 115th Annual Conference: Health for our Future. Nottingham 20 - 21 Oct 2015Conference item
T-helper cell polarisation following severe polytrauma
Torrance, H., Brohi, K., Warnes, G., Owen, H., Hinds, C., Pennington, D. and O'Dwyer, M. 2015. T-helper cell polarisation following severe polytrauma. ESICM LIVES 2015: 28th Annual Congress of European Society of Intensive Care Medicine. Berlin, Germany 03 - 07 Oct 2015 Springer Open. https://doi.org/10.1186/2197-425X-3-S1-A848Conference poster
Post-operative immune suppression is reversible with interferon gamma and independent of IL-6 pathways
Longbottom, E., Torrance, H., Owen, H., Hinds, C., Pearse, R. and O'Dwyer, M. 2015. Post-operative immune suppression is reversible with interferon gamma and independent of IL-6 pathways. ESICM LIVES 2015: 28th Annual Congress of European Society of Intensive Care Medicine. Berlin, Germany 03 - 07 Oct 2015 Springer Open. https://doi.org/10.1186/2197-425X-3-S1-A820Conference poster
The role of micrornas in the development of hospital acquired infection in polytrauma patients
Owen, H., Torrance, H., Barnes, M., Brohi, K., Knight, J., Hinds, C. and O'Dwyer, M. 2015. The role of micrornas in the development of hospital acquired infection in polytrauma patients. ESICM LIVES 2015: 28th Annual Congress of European Society of Intensive Care Medicine. Berlin, Germany 03 - 07 Oct 2015 Springer Open. https://doi.org/10.1186/2197-425X-3-S1-A35Conference item
Solution-processed anthracene-based molecular glasses as stable blue-light-emission laser gain media
Niu, Q., Zhang, Q., Xu, W., Jiang, Y., Xia, R., Bradley, D., Li, D. and Wen, S. 2015. Solution-processed anthracene-based molecular glasses as stable blue-light-emission laser gain media. Organic Electronics. 18, pp. 95-100. https://doi.org/10.1016/j.orgel.2015.01.012Article
Changes in gene expression following trauma are related to the age of transfused packed red blood cells
Torrance, H., Vivian, M., Brohi, K., Prowle, J., Pearse, R., Owen, H., Hinds, C. and O'Dwyer, M. 2015. Changes in gene expression following trauma are related to the age of transfused packed red blood cells. Journal of Trauma and Acute Care Surgery. 78 (3), pp. 535-542. https://doi.org/10.1097/TA.0000000000000534Article
The perioperative immune response
O'Dwyer, M., Owen, H. and Torrance, H. 2015. The perioperative immune response. Current Opinion in Critical Care. 21 (4), pp. 336-342. https://doi.org/10.1097/MCC.0000000000000213Article
Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation
Owen, H., Vanhees, I., Gunst, J., Van Cromphaut, S. and Van den Berghe, G. 2015. Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation. Intensive Care Medicine Experimental. 3. https://doi.org/10.1186/s40635-015-0052-3Article
Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma
Owen, H., Torrance, H., Jones, T., Pearse, R., Hinds, C., Brohi, K. and O'Dwyer, M. 2015. Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma. Journal of Trauma and Acute Care Surgery. 79 (5), pp. 766-772. https://doi.org/10.1097/TA.0000000000000850Article
Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines
Busschots, S., O'Toole, S., O'Leary, J. and Stordal, B. 2015. Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines. MethodsX. 2, pp. 8-13. https://doi.org/10.1016/j.mex.2014.11.002Article
Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer
McEvoy, L., O'Toole, S., Spillane, C., Martin, C., Gallagher, M., Stordal, B., Blackshields, G., Sheils, O. and O'Leary, J. 2015. Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer. BMC cancer. 15 (1). https://doi.org/10.1186/s12885-015-1539-8Article
Coastal risk assessment framework guidance document
Viavattene, C., Jiménez, J., Owen, D., Priest, S., Parker, D., Micou, P. and Ly, S. 2015. Coastal risk assessment framework guidance document.Project report
Teaching and learning about child rights: a study of implementation in 26 countries
Jerome, L., Emerson, L., Lundy, L. and Orr, K. 2015. Teaching and learning about child rights: a study of implementation in 26 countries. UNICEF PFP & Queen's University Belfast.Project report
Structural characterization and transdermal delivery studies on sugar microneedles: experimental and finite element modelling analyses
Loizidou, E., Williams, N., Barrow, D., Eaton, M., McCrory, J., Evans, S. and Allender, C. 2015. Structural characterization and transdermal delivery studies on sugar microneedles: experimental and finite element modelling analyses. European Journal of Pharmaceutics and Biopharmaceutics. 89, pp. 224-231. https://doi.org/10.1016/j.ejpb.2014.11.023Article
Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants
Danaei, G., Fahimi, S., Lu, Y., Zhou, B., Hajifathalian, K., Di Cesare, M., Lo, W., Cowan, M., Reis-Santos, B., Shaw, J., Bentham, J., Lin, J., Magliano, D., Bovet, P., Miranda, J., Khang, Y., Stevens, G., Riley, L., Ezzati, M. and NCD Risk Factor Collaboration (NCD-RisC) 2015. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants. Lancet Diabetes Endocrinology. 3 (8), pp. 624-637. https://doi.org/10.1016/s2213-8587(15)00129-1Article
Clinical usefulness of SPECT–CT in patients with an unexplained pain in metal on metal (MOM) total hip arthroplasty
Berber, R., Henckel, J., Khoo, M., Wan, S., Hua, J., Skinner, J. and Hart, A. 2015. Clinical usefulness of SPECT–CT in patients with an unexplained pain in metal on metal (MOM) total hip arthroplasty. The Journal of Arthroplasty. 30 (4), pp. 687-694. https://doi.org/10.1016/j.arth.2014.11.019Article
Osseointegration of acellular and cellularized osteoconductive scaffolds: is tissue engineering using mesenchymal stem cells necessary for implant fixation?
García-Gareta, E., Hua, J. and Blunn, G. 2015. Osseointegration of acellular and cellularized osteoconductive scaffolds: is tissue engineering using mesenchymal stem cells necessary for implant fixation? Journal of Biomedical Materials Research Part A. 103 (3), pp. 1067-1076. https://doi.org/10.1002/jbm.a.35256Article
Mesenchymal stem cells with increased stromal cell-derived factor 1 expression enhanced fracture healing
Ho, C., Sanghani, A., Hua, J., Coathup, M., Kalia, P. and Blunn, G. 2015. Mesenchymal stem cells with increased stromal cell-derived factor 1 expression enhanced fracture healing. Tissue Engineering Part A. 21 (3-4), pp. 594-602. https://doi.org/10.1089/ten.tea.2013.0762Article
Consideration of the bioavailability of metal/metalloid species in freshwaters: experiences regarding the implementation of biotic ligand model-based approaches in risk assessment frameworks
Rüdel, H., Diaz Muñiz, C., Garelick, H., Kandile, N., Miller, B., Pantoja Munoz, L., Peijnenburg, W., Purchase, D., Shevah, Y., Van Sprang, P., Vijer, M. and Vink, J. 2015. Consideration of the bioavailability of metal/metalloid species in freshwaters: experiences regarding the implementation of biotic ligand model-based approaches in risk assessment frameworks. Environmental Science and Pollution Research. 22 (10), pp. 7405-7421. https://doi.org/10.1007/s11356-015-4257-5Article
Identifying robust response options to manage environmental change using an Ecosystem Approach: A stress-testing case study for the UK
Brown, I., Berry, P., Everard, M., Firbank, L., Harrison, P., Lundy, L., Quine, C., Rowan, J., Wade, R. and Watts, K. 2015. Identifying robust response options to manage environmental change using an Ecosystem Approach: A stress-testing case study for the UK. Environmental Science & Policy. 52, pp. 74-88. https://doi.org/10.1016/j.envsci.2015.05.005Article
On the application of frequency selective common mode feedback for multifrequency EIT
Langlois, P., Wu, Y., Bayford, R. and Demosthenous, A. 2015. On the application of frequency selective common mode feedback for multifrequency EIT. Physiological Measurement. 36 (6), pp. 1337-1350. https://doi.org/10.1088/0967-3334/36/6/1337Article
Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry
Sniecinska-Cooper, A., Shah, A., Dimitriou, D., Iles, R., Butler, S. and Bayford, R. 2015. Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry. Journal of Chromatography B. 978-79, pp. 18-23. https://doi.org/10.1016/j.jchromb.2014.11.016Article
Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome
Sniecinska-Cooper, A., Iles, R., Butler, S., Jones, H., Bayford, R. and Dimitriou, D. 2015. Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome. Sleep Medicine. 16 (1), pp. 94-100. https://doi.org/10.1016/j.sleep.2014.09.003Article
Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells
Busschots, S., O'Toole, S., O'Leary, J. and Stordal, B. 2015. Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells. Experimental Cell Research. 336 (1), pp. 1-14. https://doi.org/10.1016/j.yexcr.2014.12.001Article
Sorption behaviours and transport potentials for selected pharmaceuticals and triclosan in two sterilised soils
Revitt, D., Balogh, T. and Jones, H. 2015. Sorption behaviours and transport potentials for selected pharmaceuticals and triclosan in two sterilised soils. Journal of Soils and Sediments. 15 (3), pp. 594-606. https://doi.org/10.1007/s11368-014-1025-yArticle
Narrowing the focus: public understanding of flood maps in the River Thames catchment
Priest, S., Pardoe, J., McCarthy, S. and Viavattene, C. 2011. Narrowing the focus: public understanding of flood maps in the River Thames catchment. in: Zenz, G. and Hornich, R. (ed.) Urban Flood Risk Management: Approaches to enhance resilience of communities, Proceedings of the International Symposium, 21st-23rd September 2011 Graz Technischen Universitat Graz. pp. 309-314Book chapter
Efficient generation of transgenic mice by lentivirus-mediated modification of spermatozoa
Chandrashekran, A., Sarkar, R., Thrasher, A., Fraser, S., Dibb, N., Casimir, C., Winston, R. and Readhead, C. 2014. Efficient generation of transgenic mice by lentivirus-mediated modification of spermatozoa. The FASEB Journal. 28 (2), pp. 569-576. https://doi.org/10.1096/fj.13-233999Article
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