Detection of extended-spectrum β-lactamase and carbapenemase activity in Gram-negative bacilli using liquid chromatography - tandem mass spectrometry
Article
Serafim, V., Shah, A., Licker, M., Horhat, F., Vulpie, S., Musuroi, C. and Muntean, D. 2020. Detection of extended-spectrum β-lactamase and carbapenemase activity in Gram-negative bacilli using liquid chromatography - tandem mass spectrometry. Infection and Drug Resistance. 13, pp. 4021-4029. https://doi.org/10.2147/IDR.S267160
Type | Article |
---|---|
Title | Detection of extended-spectrum β-lactamase and carbapenemase activity in Gram-negative bacilli using liquid chromatography - tandem mass spectrometry |
Authors | Serafim, V., Shah, A., Licker, M., Horhat, F., Vulpie, S., Musuroi, C. and Muntean, D. |
Abstract | PURPOSE: Several mass spectrometry-based methods for antimicrobial sensitivity testing have been described in recent years. They offer an alternative to commercially available testing systems which were considered to have disadvantages in terms of cost- and time-efficiency. The aim of this study was to develop a LC-MS/MS-based antibiotic hydrolysis assay for evaluating antimicrobial resistance of Gram-negative bacteria. |
Keywords | Gram-negative, LC-MS/MS, antimicrobial, mass spectrometry, resistance, β-lactamases |
Publisher | Dovepress |
Journal | Infection and Drug Resistance |
ISSN | 1178-6973 |
Publication dates | |
10 Nov 2020 | |
Publication process dates | |
Deposited | 11 Sep 2020 |
Accepted | 07 Sep 2020 |
Output status | Published |
Publisher's version | |
Accepted author manuscript | License |
Accepted author manuscript | License |
Accepted author manuscript | License |
Copyright Statement | © 2020 Serafim et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
Digital Object Identifier (DOI) | https://doi.org/10.2147/IDR.S267160 |
Language | English |
https://repository.mdx.ac.uk/item/890zx
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