pH regulation of penicillin production in Aspergillus nidulans
Article
Shah, A., Tilburn, J., Adlard, M. and Arst, H. 1991. pH regulation of penicillin production in Aspergillus nidulans. FEMS microbiology letters. 77 (2-3), pp. 209-212. https://doi.org/10.1111/j.1574-6968.1991.tb04349.x
Type | Article |
---|---|
Title | pH regulation of penicillin production in Aspergillus nidulans |
Authors | Shah, A., Tilburn, J., Adlard, M. and Arst, H. |
Abstract | As shown by both bioassay and high-performance liquid chromatographic (HPLC) analysis, penicillin G production by Aspergillus nidulans is subject to regulation by the pH of the growth medium. Penicillin titres were highest at alkaline pH and in strains carrying mutations in the regulatory gene pacC which mimics the effects of growth at alkaline pH. They were lowest at acid pH and in strains carrying mutations in the palA, palB, palC, palE or palF genes which mimic the effects of growth at acid pH. |
Research Group | Biomarkers for Cancer group |
Publisher | Oxford University Press (OUP) |
Journal | FEMS microbiology letters |
ISSN | 0378-1097 |
Publication dates | |
01 Jan 1991 | |
Publication process dates | |
Deposited | 02 Feb 2018 |
Accepted | 09 Nov 1990 |
Output status | Published |
Digital Object Identifier (DOI) | https://doi.org/10.1111/j.1574-6968.1991.tb04349.x |
Language | English |
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