Amino acid neurotransmitters: separation approaches and diagnostic value

Article

Shah, A., Crespi, F. and Heidbreder, C. 2002. Amino acid neurotransmitters: separation approaches and diagnostic value. Journal of Chromatography B. 781 (1-2), pp. 151-163. https://doi.org/10.1016/S1570-0232(02)00621-9
TypeArticle
TitleAmino acid neurotransmitters: separation approaches and diagnostic value
AuthorsShah, A., Crespi, F. and Heidbreder, C.
Abstract

Amino acids in the central nervous system can be divided into non-neurotransmitter or neurotransmitter depending on their function. The measurement of these small molecules in brain tissue and extracellular fluid has been used to develop effective treatment strategies for neuropsychiatric and neurodegenerative diseases and for the diagnosis of such pathologies. Here we describe the separation and detection techniques that have been used for the measurement of amino acids at trace levels in brain tissue and dialysates. An overview of the function of amino acid transmitters in the brain is given. In addition, the type of sampling techniques that are used for the determination of amino acid levels in the brain is described.

PublisherElsevier
JournalJournal of Chromatography B
ISSN1570-0232
Publication dates
Online16 Sep 2002
Print05 Dec 2002
Publication process dates
Deposited03 Nov 2017
Accepted21 Oct 2002
Output statusPublished
Digital Object Identifier (DOI)https://doi.org/10.1016/S1570-0232(02)00621-9
LanguageEnglish
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