Patel, N.; Ghali, L.; Roitt, I.; Pantoja Munoz, L.; Bayford, R.

Exploiting the efficacy of Tyro3 and folate receptors to enhance the delivery of gold nanoparticles into colorectal cancer cells in vitro

Article

Patel, N., Ghali, L., Roitt, I., Pantoja Munoz, L. and Bayford, R. 2021. Exploiting the efficacy of Tyro3 and folate receptors to enhance the delivery of gold nanoparticles into colorectal cancer cells in vitro. Nanoscale Advances. 3 (18), pp. 5373-5386. https://doi.org/10.1039/d1na00318f

Publication dates
Type	Article
Title	Exploiting the efficacy of Tyro3 and folate receptors to enhance the delivery of gold nanoparticles into colorectal cancer cells in vitro
Authors	Patel, N., Ghali, L., Roitt, I., Pantoja Munoz, L. and Bayford, R.
Abstract	Colorectal cancer (CRC) is the fourth most common cancer in the world. Due to its asymptomatic nature, CRC is diagnosed at an advanced stage where the survival rate is <5%. Besides, CRC treatment using chemotherapy, radiotherapy and surgery often causes undesirable side-effects. As such, gold nanoparticles (GNPs) are envisaged in the field for the diagnosis and treatment of CRC. GNPs have unique physical, chemical and electrical properties at the nanoscale which make them suitable for application in biomedicine. However, for GNPs to become clinically effective, their internalisation efficiency in cancer cells must be enhanced. Folate receptor-α (FR) is overexpressed in CRC cells wherein FR helps in the uptake of folic acid within the cells. Tyro3, a novel tyrosine kinase receptor, drives cell proliferation and its overexpression is correlated with poor prognosis in CRC. Their upregulated expression in CRC cells relative to normal cells makes them an ideal target for GNPs using active targeting. Therefore, in this study receptors FR and Tyro3 were simultaneously targeted using specific antibody-coated GNPs in order to enhance the uptake and internalisation of GNPs in CRC cells in vitro. Four different types of coated-GNPs were synthesised GNPs-PEG, GNPs-anti-FR, GNPs-anti-Tyro3 and GNPs-anti-(FR + Tyro3) and incubated (0–50 ng) with three CRC cell lines namely CRL1790, CRL2159 and HCT116. Simultaneous targeting of these receptors by GNPs-anti-(FR + Tyro3) was found to be the most effective in internalisation in CRC cells compared with GNPs targeted singly to FR or Tyro3 (p <0.05). Besides this, results show that Tyro3 mediated similar internalisation efficacy to FR (p <0.05) in CRC cells using ICP-OES.
Keywords	General Engineering, General Materials Science, General Chemistry, Atomic and Molecular Physics, and Optics, Bioengineering
Publisher	Royal Society of Chemistry (RSC)
Journal	Nanoscale Advances
ISSN	2516-0230
Electronic	2516-0230
Online	15 Jul 2021
Publication process dates
Deposited	26 Aug 2021
Submitted	29 Apr 2021
Accepted	15 Jul 2021
Output status	Published
Publisher's version	d1na00318f.pdf d1na00318f_VoR.pdf File Access Level Open
Copyright Statement	© 2021 The Author(s). Published by the Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence
Digital Object Identifier (DOI)	https://doi.org/10.1039/d1na00318f
Language	English

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A parametric model for the changes in the complex valued conductivity of a lung during tidal breathing

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Clinical performance of a novel textile interface for neonatal chest electrical impedance tomography

Sophocleous, L., Frerichs, I., Miedema, M., Kallio, M., Papadouri, T., Karaoli, C., Becher, T., Tingay, D., van Kaam, A., Bayford, R. and Waldmann, A. 2018. Clinical performance of a novel textile interface for neonatal chest electrical impedance tomography. Physiological Measurement. 39 (4). https://doi.org/10.1088/1361-6579/aab513

Optimizing drug delivery using arsenic trioxide encapsulated liposomes for increasing the efficacy in treating cervical cancer in vitro

Akhtar, A., Wen, S., Wang, X., Ghali, L. and Bell, C. 2016. Optimizing drug delivery using arsenic trioxide encapsulated liposomes for increasing the efficacy in treating cervical cancer in vitro. International Conference on Nanomedicine and Nanobiotechnology 2016 – ICONAN 2016. Paris, France 28 - 30 Sep 2016 pp. 16

A human-machine interface using electrical impedance tomography for hand prosthesis control

Wu, Yu, Jiang, Dai, Liu, Xiao, Bayford, Richard and Demosthenous, A. 2018. A human-machine interface using electrical impedance tomography for hand prosthesis control. IEEE Transactions on Biomedical Circuits and Systems. 12 (6), pp. 1322-1333. https://doi.org/10.1109/TBCAS.2018.2878395

A high frame rate wearable EIT system using active electrode ASICs for lung respiration and heart rate monitoring

Wu, Y., Jiang, D., Bardill, A., de Gelidi, S., Bayford, R. and Demosthenous, A. 2018. A high frame rate wearable EIT system using active electrode ASICs for lung respiration and heart rate monitoring. IEEE Transactions on Circuits and Systems I: Regular Papers. 65 (11), pp. 3810-3820. https://doi.org/10.1109/TCSI.2018.2858148

Optimized breath detection algorithm in electrical impedance tomography

Khodadad, D., Nordebo, S., Müller, B., Waldmann, A., Yerworth, R., Becher, T., Frerichs, I., Sophocleous, L., van Kaam, A., Miedema, M., Seifnaraghi, N. and Bayford, R. 2018. Optimized breath detection algorithm in electrical impedance tomography. Physiological Measurement. 39 (9). https://doi.org/10.1088/1361-6579/aad7e6

Effective delivery of arsenic trioxide to HPV-positive cervical cancer cells using optimised liposomes: a size and charge study

Akhtar, A., Wang, S., Ghali, L., Bell, C. and Wen, S. 2018. Effective delivery of arsenic trioxide to HPV-positive cervical cancer cells using optimised liposomes: a size and charge study. International Journal of Molecular Sciences. 19 (4), pp. 1-14. https://doi.org/10.3390/ijms19041081

Basic electrical impedance tomography

Bayford, R. 2018. Basic electrical impedance tomography. in: Simini, F. and Bertemes-Filho, P. (ed.) Bioimpedance in Biomedical Applications and Research Cham, Switzerland Springer. pp. 29-44

Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine

Kvirkvelia, N., Chikadze, N., Makinde, J., McBride, J., Porakishvili, N., Hills, F., Martensen, P., Justesen, J., Delves, P., Lund, T. and Roitt, I. 2018. Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine. Clinical & Experimental Immunology. 193 (1), pp. 73-83. https://doi.org/10.1111/cei.13131

Effect of anthropogenic pollution on the fitness of tetracycline sensitive Shigella flexneri in Thames river water

Maruzani, R., Canali, A., Serafim, V., Pantoja Munoz, L., Shah, A., Perito, B. and Marvasi, M. 2018. Effect of anthropogenic pollution on the fitness of tetracycline sensitive Shigella flexneri in Thames river water. Journal of Environmental Chemical Engineering. 6 (1), pp. 19-27. https://doi.org/10.1016/j.jece.2017.11.069

Fitness analysis of tetracycline resistant and sensitive Shigella flexneri in lethal and sub-lethal concentrations of tetracycline in Thames river water microcosms

Maruzani, R., Shah, A., Pantoja Munoz, L. and Marvasi, M. 2017. Fitness analysis of tetracycline resistant and sensitive Shigella flexneri in lethal and sub-lethal concentrations of tetracycline in Thames river water microcosms. University Research Students Summer Conference 2017. London 2017

Breath detection using short-time Fourier transform analysis in electrical impedance tomography

Khodadad, D., Nordebo, S., Seifnaraghi, N., Waldmann, A., Müller, B. and Bayford, R. 2017. Breath detection using short-time Fourier transform analysis in electrical impedance tomography. 2017 XXXIInd General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS). Montreal, QC, Canada 19 - 23 Aug 2017 Institute of Electrical and Electronics Engineers (IEEE). pp. 2185-2187 https://doi.org/10.23919/URSIGASS.2017.8105231

Parameter studies on optimal absorption and electrophoretic resonances in lossy media

Nordebo, S., Dalarsson, M., Ivanenko, Y., Sjöberg, D. and Bayford, R. 2017. Parameter studies on optimal absorption and electrophoretic resonances in lossy media. 2017 XXXIInd General Assembly and Scientific Symposium of the International Union of Radio Science (URSI GASS). Montreal 19 - 23 Aug 2017 Institute of Electrical and Electronics Engineers (IEEE). pp. 1768-1769 https://doi.org/10.23919/URSIGASS.2017.8105294

Toward on-demand deep brain stimulation using online Parkinson’s disease prediction driven by dynamic detection

Mohammed, A., Zamani, M., Bayford, R. and Demosthenous, A. 2017. Toward on-demand deep brain stimulation using online Parkinson’s disease prediction driven by dynamic detection. IEEE Transactions on Neural Systems and Rehabilitation Engineering. 25 (12), pp. 2441-2452. https://doi.org/10.1109/TNSRE.2017.2722986

Estimation of thorax shape for forward modelling in lungs EIT

Seifnaraghi, N., Tizzard, A., de Gelidi, S., Khodadad, D., Nordebo, S., Van Kaam, A., Frerichs, I., Waldmann, A., Sorantin, E., Tschauner, S., Demosthenous, A., Christofides, S. and Bayford, R. 2017. Estimation of thorax shape for forward modelling in lungs EIT. 18th International Conference on Biomedical Applications of Electrical Impedance Tomography. Hanover, New Hampshire, USA 21 - 24 Jun 2017 Thayer School of Engineering at Dartmouth. pp. 58-58 https://doi.org/10.5281/zenodo.557093

DICOM for EIT

Yerworth, R. and Bayford, R. 2017. DICOM for EIT. 18th International Conference on Biomedical Applications of Electrical Impedance Tomography. Hanover, New Hampshire, USA 21 - 24 Jun 2017 Thayer School of Engineering at Dartmouth. pp. 46-46 https://doi.org/10.5281/zenodo.557093

Torso shape detection to improve lung monitoring

de Gelidi, S., Bardill, A., Wu, Y., Demosthenous, A., Tizzard, A. and Bayford, R. 2017. Torso shape detection to improve lung monitoring. 18th International Conference on Biomedical Applications of Electrical Impedance Tomography. Hanover, New Hampshire, USA 21 - 24 Jun 2017 Thayer School of Engineering at Dartmouth. pp. 25-25 https://doi.org/10.5281/zenodo.557093

Rapid generation of subject-specific thorax forward models

Tizzard, A. and Bayford, R. 2017. Rapid generation of subject-specific thorax forward models. 18th International Conference on Biomedical Applications of Electrical Impedance Tomography. Hanover, New Hampshire, USA 21 - 24 Jun 2017 Thayer School of Engineering at Dartmouth. pp. 20-20 https://doi.org/10.5281/zenodo.557093

Nanoparticle electrical impedance tomography

Bayford, R., Nordebo, S., Roitt, I., Rademacher, T., Damaso, R., Wu, Y., Seifnaraghi, N. and Demosthenous, A. 2017. Nanoparticle electrical impedance tomography. 18th International Conference on Biomedical Applications of Electrical Impedance Tomography. Hanover, New Hampshire, USA 21 - 24 Jun 2017 Thayer School of Engineering at Dartmouth. pp. 56-56 https://doi.org/10.5281/zenodo.557093

Absorption and optimal plasmonic resonances for small ellipsoidal particles in lossy media

Dalarsson, M., Nordebo, S., Sjöberg, D. and Bayford, R. 2017. Absorption and optimal plasmonic resonances for small ellipsoidal particles in lossy media. Journal of Physics D: Applied Physics. 50 (34). https://doi.org/10.1088/1361-6463/aa7c8a

Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro

Gromnicova, R., Davies, H., Sreekanthreddy, P., Romero, I., Lund, T., Roitt, I., Phillips, J. and Male, D. 2013. Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro. PLoS ONE. 8 (12), pp. 1-10. https://doi.org/10.1371/journal.pone.0081043

Continuous Regional Analysis Device for Neonates Lung (CRADL)

Bayford, R., Tizzard, A., Frerichs, I., Weiler, N., Karaoli, C., Christofides, S., Yiannakkaras, C., Rimensberger, P., Nordebo, S., Böhm, S., van Kaam, A., Fifield, B., Knox, C., Steuten, L., de Graaf, G., Yerworth, R., Butterworth, M. and Demosthenous, A. 2016. Continuous Regional Analysis Device for Neonates Lung (CRADL). MEDICON 2016: XIV Mediterranean Conference on Medical and Biological Engineering and Computing 2016. Paphos, Cyprus. 31 Mar - 02 Apr 2016 Springer. pp. 172 https://doi.org/10.1007/978-3-319-32703-7_35

Microbial DNA analysis by MALDI-TOF mass spectrometry

Honisch, C., Serafim, V., Hennessy, N., Allen, D., Ring, C., Pantoja Munoz, L., Gharbia, S., Shah, A. and Shah, H. 2017. Microbial DNA analysis by MALDI-TOF mass spectrometry. in: Shah, H. and Gharbia, S. (ed.) MALDI-TOF and Tandem MS for Clinical Microbiology Oxford Wiley. pp. 187-209

A wideband low-distortion CMOS current driver for tissue impedance analysis

Constantinou, L., Bayford, R. and Demosthenous, A. 2015. A wideband low-distortion CMOS current driver for tissue impedance analysis. IEEE Transactions on Circuits and Systems II: Express Briefs. 62 (2), pp. 154-158. https://doi.org/10.1109/tcsii.2014.2387632

Why is EIT so hard, and what are we doing about it?

Adler, A., Grychtol, B. and Bayford, R. 2015. Why is EIT so hard, and what are we doing about it? Physiological Measurement. 36 (6), pp. 1067-1073. https://doi.org/10.1088/0967-3334/36/6/1067

Medical Physics: forming and testing solutions to clinical problems

Tsapaki, V. and Bayford, R. 2015. Medical Physics: forming and testing solutions to clinical problems. Physica Medica. 31 (7), pp. 738-740. https://doi.org/10.1016/j.ejmp.2015.05.017

Patient specific Parkinson's disease detection for adaptive deep brain stimulation

Mohammed, A., Zamani, M., Bayford, R. and Demosthenous, A. 2015. Patient specific Parkinson's disease detection for adaptive deep brain stimulation. 2015 37th Annual International Conference Of the IEEE Engineering In Medicine And Biology Society (EMBC). Milan, Italy 25 Aug 2015 IEEE. pp. 1528-1531

Lipoxin A4 selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression

Simoes, R., De-Brito, N., Cunha-Costa, H., Morandi, V., Fierro, I., Roitt, I. and Barja-Fidalgo, C. 2017. Lipoxin A4 selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression. International Journal of Cancer. 140 (2), pp. 346-357. https://doi.org/10.1002/ijc.30424

16th International Conference on Electrical Bio-impedance and 17th International Conference on Biomedical Applications of Electrical Impedance Tomography (EIT) [Editorial]

Bayford, R. and Olimar, S. 2017. 16th International Conference on Electrical Bio-impedance and 17th International Conference on Biomedical Applications of Electrical Impedance Tomography (EIT) [Editorial]. Physiological Measurement. 38 (6), pp. E8-E9. https://doi.org/10.1088/1361-6579/aa6a5c

Emerging applications of nanotechnology for diagnosis and therapy of disease: a review

Bayford, R., Rademacher, T., Roitt, I. and Wang, S. 2017. Emerging applications of nanotechnology for diagnosis and therapy of disease: a review. Physiological Measurement. 38 (8). https://doi.org/10.1088/1361-6579/aa7182

A study of the inhibition of biofilm formation on multiple surfaces by a biosurfactant containing four discrete lipopeptides

Khonsari, S., Gonzalez Baez, A., Nguyen, H., Pantoja Munoz, L. and Purchase, D. 2017. A study of the inhibition of biofilm formation on multiple surfaces by a biosurfactant containing four discrete lipopeptides. Microbiology Society Annual Conference. Edinburgh, United Kingdom 03 - 06 Apr 2017

On the physical limitations for radio frequency absorption in gold nanoparticle suspensions

Nordebo, S., Dalarsson, M., Ivanenko, Y., Sjoeberg, D. and Bayford, R. 2017. On the physical limitations for radio frequency absorption in gold nanoparticle suspensions. Journal of Physics D: Applied Physics. 50 (15). https://doi.org/10.1088/1361-6463/aa5a89

Modelling and validating three dimensional human normal cervix and cervical cancer tissues in vitro

Zuk, A., Wen, S., Dilworth, S., Li, D. and Ghali, L. 2017. Modelling and validating three dimensional human normal cervix and cervical cancer tissues in vitro. Journal of Biomedical Research. 31 (3), pp. 240-247. https://doi.org/10.7555/JBR.31.20160150

Rapid identification of E. coli bacteriophages using mass spectrometry

Serafim, V., Ring, C., Pantoja Munoz, L., Shah, H. and Shah, A. 2017. Rapid identification of E. coli bacteriophages using mass spectrometry. Journal of Proteomics and Enzymology. 6 (1), pp. 1-5. https://doi.org/10.4172/2470-1289.1000130

Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment

Owen, H., Appiah, S., Hasan, N., Ghali, L., Elayat, G. and Bell, C. 2017. Phytochemical modulation of apoptosis and autophagy: strategies to overcome chemoresistance in leukaemic stem cells in the bone marrow microenvironment. in: Zeng, B. and Zhao, K. (ed.) Neurobiology of Chinese Herb Medicine Elsevier.

Heparan sulfate disaccharide measurement from biological samples using pre-column derivatization, UPLC-MS and single ion monitoring

Antia, I., Yagnik, D., Pantoja Munoz, L., Shah, A. and Hills, F. 2017. Heparan sulfate disaccharide measurement from biological samples using pre-column derivatization, UPLC-MS and single ion monitoring. Analytical Biochemistry. 530, pp. 17-30. https://doi.org/10.1016/j.ab.2017.04.019

Detecting colorectal cancer using electrical impedance spectroscopy: an ex vivo feasibility study

Pathiraja, A., Ziprin, P., Shiraz, A., Mirnezami, R., Tizzard, A., Brown, B., Demosthenous, A. and Bayford, R. 2017. Detecting colorectal cancer using electrical impedance spectroscopy: an ex vivo feasibility study. Physiological Measurement. 38 (6), pp. 1278-1288. https://doi.org/10.1088/1361-6579/aa68ce

Detection of the tau protein in human serum by a sensitive four-electrode electrochemical biosensor

Wang, S., Acha, D., Shah, A., Hills, F., Roitt, I., Demosthenous, A. and Bayford, R. 2017. Detection of the tau protein in human serum by a sensitive four-electrode electrochemical biosensor. Biosensors and Bioelectronics. 92, pp. 482-488. https://doi.org/10.1016/j.bios.2016.10.077

Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers

Akhtar, A., Wang, S., Ghali, L., Bell, C. and Wen, S. 2017. Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers. Journal of Biomedical Research. 31 (3), pp. 177-188. https://doi.org/10.7555/JBR.31.20160059

Analysis and compensation for errors in electrical impedance tomography images and ventilation-related measures due to serial data collection

Yerworth, R., Frerichs, I. and Bayford, R. 2017. Analysis and compensation for errors in electrical impedance tomography images and ventilation-related measures due to serial data collection. Journal of Clinical Monitoring and Computing. 31 (5), pp. 1093-1101. https://doi.org/10.1007/s10877-016-9920-y

EIT2015: promoting electrical impedance tomography as a non-invasive monitoring technology

Bayford, R. and Solà, J. 2016. EIT2015: promoting electrical impedance tomography as a non-invasive monitoring technology. Physiological Measurement. 37 (6), pp. E3-E4. https://doi.org/10.1088/0967-3334/37/6/E3

A novel active electrode IC for wearable EIT system

Wu, Y., Langlois, P., Bayford, R. and Demosthenous, A. 2016. A novel active electrode IC for wearable EIT system. 16th International Conference on Electrical Bio-Impedance (ICEBI) and 17th International Conference on Electrical Impedance Tomography (EIT). Stockholm 19 - 23 Jun 2016 Zenodo. pp. 138 https://doi.org/10.5281/zenodo.55753

Alternate algorithm to reconstruct shape in wearable device

Tizzard, A., Demosthenous, A. and Bayford, R. 2016. Alternate algorithm to reconstruct shape in wearable device. 16th International Conference on Electrical Bio-Impedance (ICEBI) and 17th International Conference on Electrical Impedance Tomography (EIT). Stockholm 19 - 23 Jun 2016 Zenodo. pp. 128 https://doi.org/10.5281/zenodo.55753

The role of ectopic human chorionic gonadotropin beta subunit in inducing epithelial mesenchymal transition in human keratinocytes and its possible pathways

Wen, S., Li, D., Farshori, Z., Wang, X. and Ghali, L. 2015. The role of ectopic human chorionic gonadotropin beta subunit in inducing epithelial mesenchymal transition in human keratinocytes and its possible pathways. British Pharmacological Society Winder Conference 2014. Queen Elizabeth II Conference Centre London 14 - 17 Dec 2014

Design of a CMOS active electrode IC for wearable electrical impedance tomography systems

Wu, Y., Langlois, P., Bayford, R. and Demosthenous, A. 2016. Design of a CMOS active electrode IC for wearable electrical impedance tomography systems. 2016 IEEE International Symposium Circuits and Systems (ISCAS). Montreal, QC, Canada 22 - 25 May 2016 Institute of Electrical and Electronics Engineers (IEEE). pp. 846-849 https://doi.org/10.1109/ISCAS.2016.7527373

Inhibition of HIV virus by neutralizing Vhh attached to dual functional liposomes encapsulating dapivirine

Wang, S., Michiels, J., Ariën, K., New, R., Vanham, G. and Roitt, I. 2016. Inhibition of HIV virus by neutralizing Vhh attached to dual functional liposomes encapsulating dapivirine. Nanoscale Research Letters. 11 (1), pp. 1-10. https://doi.org/10.1186/s11671-016-1558-7

The mechanisms of detoxification of As(III), dimethylarsinic acid (DMA) and As(V) in the microalga Chlorella vulgaris

Pantoja Munoz, L., Purchase, D., Jones, H., Raab, A., Urgast, D., Feldmann, J. and Garelick, H. 2016. The mechanisms of detoxification of As(III), dimethylarsinic acid (DMA) and As(V) in the microalga Chlorella vulgaris. Aquatic Toxicology. 175, pp. 56-72. https://doi.org/10.1016/j.aquatox.2016.02.020

Therapeutic potential of delivering arsenic trioxide into HPV-infected cervical cancer cells using liposomal nanotechnology

Wang, X., Li, D., Ghali, L., Xia, R., Pantoja Munoz, L., Garelick, H., Bell, C. and Wen, S. 2016. Therapeutic potential of delivering arsenic trioxide into HPV-infected cervical cancer cells using liposomal nanotechnology. Nanoscale Research Letters. 11 (1), pp. 1-8. https://doi.org/10.1186/s11671-016-1307-y

XVth International Conference on Electrical Bio-Impedance and the XIVth Conference on Electrical Impedance Tomography (Heilbad Heiligenstadt, Germany, 22–25 April 2013)

Bayford, R. and Pliquett, U. 2014. XVth International Conference on Electrical Bio-Impedance and the XIVth Conference on Electrical Impedance Tomography (Heilbad Heiligenstadt, Germany, 22–25 April 2013). Physiological Measurement. 35 (6), pp. 945-946. https://doi.org/10.1088/0967-3334/35/6/915

MPS: improving exact string matching through pattern character frequency, journal of data processing

Sahota, V., Li, M. and Bayford, R. 2013. MPS: improving exact string matching through pattern character frequency, journal of data processing. Journal of Data Processing. 3 (3), pp. 127-137.

The effect of serial data collection on the accuracy of electrical impedance tomography images

Yerworth, R. and Bayford, R. 2013. The effect of serial data collection on the accuracy of electrical impedance tomography images. Physiological Measurement. 34 (6), pp. 659-669. https://doi.org/10.1088/0967-3334/34/6/659

Bioimpedance imaging: an overview of potential clinical applications

Bayford, R. and Tizzard, A. 2012. Bioimpedance imaging: an overview of potential clinical applications. Analyst. 137 (20), pp. 4635-4643. https://doi.org/10.1039/C2AN35874C

Whither lung EIT: where are we, where do we want to go and what do we need to get there?

Adler, A., Amato, M., Arnold, J., Bayford, R., Bodenstein, M. and Böhm, S. 2012. Whither lung EIT: where are we, where do we want to go and what do we need to get there? Physiological Measurement. 33 (5), pp. 679-694. https://doi.org/10.1088/0967-3334/33/5/679

A cable theory based biophysical model of resistance change in crab peripheral nerve and human cerebral cortex during neuronal depolarisation: implications for electrical impedance tomography of fast neural activity in the brain

Liston, A., Bayford, R. and Holder, D. 2012. A cable theory based biophysical model of resistance change in crab peripheral nerve and human cerebral cortex during neuronal depolarisation: implications for electrical impedance tomography of fast neural activity in the brain. Med Biol Eng Comput. 50 (5), pp. 425-437. https://doi.org/10.1007/s11517-012-0901-0

Consideration of the bioavailability of metal/metalloid species in freshwaters: experiences regarding the implementation of biotic ligand model-based approaches in risk assessment frameworks

Rüdel, H., Diaz Muñiz, C., Garelick, H., Kandile, N., Miller, B., Pantoja Munoz, L., Peijnenburg, W., Purchase, D., Shevah, Y., Van Sprang, P., Vijer, M. and Vink, J. 2015. Consideration of the bioavailability of metal/metalloid species in freshwaters: experiences regarding the implementation of biotic ligand model-based approaches in risk assessment frameworks. Environmental Science and Pollution Research. 22 (10), pp. 7405-7421. https://doi.org/10.1007/s11356-015-4257-5

On the application of frequency selective common mode feedback for multifrequency EIT

Langlois, P., Wu, Y., Bayford, R. and Demosthenous, A. 2015. On the application of frequency selective common mode feedback for multifrequency EIT. Physiological Measurement. 36 (6), pp. 1337-1350. https://doi.org/10.1088/0967-3334/36/6/1337

Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry

Sniecinska-Cooper, A., Shah, A., Dimitriou, D., Iles, R., Butler, S. and Bayford, R. 2015. Determination of urinary cortisol, cortisone and 6-sulfatoxymelatonin using dilute and shoot ultra-high pressure liquid chromatography-tandem mass spectrometry. Journal of Chromatography B. 978-79, pp. 18-23. https://doi.org/10.1016/j.jchromb.2014.11.016

Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome

Sniecinska-Cooper, A., Iles, R., Butler, S., Jones, H., Bayford, R. and Dimitriou, D. 2015. Abnormal secretion of melatonin and cortisol in relation to sleep disturbances in children with Williams syndrome. Sleep Medicine. 16 (1), pp. 94-100. https://doi.org/10.1016/j.sleep.2014.09.003

The role of vitamin In type 2 diabetes

Ali, A., Appiah, S., Shah, A. and Ghali, L. 2014. The role of vitamin In type 2 diabetes. Middlesex University Postgraduate Summer Conference. London, UK 19 Jun 2014

Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines

Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2014. Impact of inulin on bile acids induced colon cancer: antioxidant and anti-proliferative effect of inulin on HCT 116 cell lines. Middlesex University Postgraduate Summer Conference. London, UK 19 Jun 2014

Impact of inulin on bile acids induced colon cancer

Afolabi, B., Appiah, S., Pachenari, A. and Ghali, L. 2013. Impact of inulin on bile acids induced colon cancer. Third AACR International Conference on Frontiers in Basic Cancer Research. National Harbor, MD, United States 18 - 22 Sep 2013

The mechanisms of arsenic detoxification by the green microalgae chlorella vulgaris

Pantoja Munoz, L. 2014. The mechanisms of arsenic detoxification by the green microalgae chlorella vulgaris. PhD thesis Middlesex University Science and Technology

The mechanisms of arsenic bioremediation from water by the green microalgae Chlorella vulgaris

Pantoja Munoz, L., Purchase, D., Jones, H., Feldmann, J. and Garelick, H. 2014. The mechanisms of arsenic bioremediation from water by the green microalgae Chlorella vulgaris. THE BNASS / TraceSpec Tandem Conference. Aberdeen, Scotland, UK 31 Aug - 04 Sep 2014

Wearable sensors for patient-specific boundary shape estimation to improve the forward model for electrical impedance tomography (EIT) of neonatal lung function

Khor, J., Tizzard, A., Demosthenous, A. and Bayford, R. 2014. Wearable sensors for patient-specific boundary shape estimation to improve the forward model for electrical impedance tomography (EIT) of neonatal lung function. Physiological Measurement. 35 (6), pp. 1149-1161. https://doi.org/10.1088/0967-3334/35/6/1149

High-power CMOS current driver with accurate transconductance for electrical impedance tomography

Constantinou, L., Triantis, I., Bayford, R. and Demosthenous, A. 2014. High-power CMOS current driver with accurate transconductance for electrical impedance tomography. IEEE Transactions on Biomedical Circuits and Systems. 8 (4), pp. 575-583. https://doi.org/10.1109/TBCAS.2013.2285481

Enhanced determination of As-phytochelatin complexes in Chlorella vulgaris using focused sonication for extraction of water-soluble species

Pantoja Munoz, L., Purchase, D., Jones, H., Feldmann, J. and Garelick, H. 2014. Enhanced determination of As-phytochelatin complexes in Chlorella vulgaris using focused sonication for extraction of water-soluble species. Analytical Methods. 6 (3), pp. 791-797. https://doi.org/10.1039/C3AY41629A

The removal of arsenate from water using iron-modified diatomite (D-Fe): isotherm and column experiments

Pantoja Munoz, L., Jones, H., Garelick, H., Mohamedbakr, H. and Burkitbayev, M. 2014. The removal of arsenate from water using iron-modified diatomite (D-Fe): isotherm and column experiments. Environmental Science and Pollution Research. 21 (1), pp. 495-506. https://doi.org/10.1007/s11356-013-1891-7

Reduced E-cadherin expression correlates with disease progression in Paget's disease of the vulva but not Paget's disease of the breast

Ellis, P., Cano, S., Fear, M., Kelsell, D., Ghali, L., Crow, J., Perrett, C. and MacLean, A. 2008. Reduced E-cadherin expression correlates with disease progression in Paget's disease of the vulva but not Paget's disease of the breast. Modern Pathology. 21 (10), pp. 1192-1199. https://doi.org/10.1038/modpathol.2008.50

hCGβ expression by cervical squamous carcinoma - in vivohistological association with tumour invasion and apoptosis

Li, D., Wen, S., Ghali, L., Al-Shalabi, F., Docherty, S., Purkis, P. and Iles, R. 2008. hCGβ expression by cervical squamous carcinoma - in vivohistological association with tumour invasion and apoptosis. Histopathology. 53 (2), pp. 147-155. https://doi.org/10.1111/j.1365-2559.2008.03082.x

Comparison of the calibration standards of three commercially available multiplex kits for human cytokine measurement to WHO standards reveals striking differences

Nechansky, A., Grunt, S., Roitt, I. and Kircheis, R. 2008. Comparison of the calibration standards of three commercially available multiplex kits for human cytokine measurement to WHO standards reveals striking differences. Biomarker Insights. 3, pp. 227-235.

The influence of ligand organization on the rate of uptake of gold nanoparticles by colorectal cancer cells

Lund, T., Callaghan, M., Williams, P., Turmaine, M., Bachmann, C., Rademacher, T., Roitt, I. and Bayford, R. 2011. The influence of ligand organization on the rate of uptake of gold nanoparticles by colorectal cancer cells. Biomaterials. 32 (36), pp. 9776-9784. https://doi.org/10.1016/j.biomaterials.2011.09.018

Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA)

McBride, J., Gabriel, F., Fordham, J., Kolind, T., Barcenas-Morales, G., Isenberg, D., Swana, M., Delves, P., Lund, T., Cree, I. and Roitt, I. 2008. Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA). Clinical Chemistry. 54 (5), pp. 883-890. https://doi.org/10.1373/clinchem.2007.098418

hCGβ expression by cervical squamous carcinoma: in vivo histological association with tumour invasion and apoptosis

Li, D., Wen, S., Ghali, L., Al-Shalabi, F., Docherty, S., Purkis, P. and Iles, R. 2008. hCGβ expression by cervical squamous carcinoma: in vivo histological association with tumour invasion and apoptosis. Histopathology. 53 (2), pp. 147-155. https://doi.org/10.1111/j.1365-2559.2008.03082.x

Axl promotes cutaneous squamous cell carcinoma survival through negative regulation of pro-apoptotic Bcl-2 family members

Papadakis, E., Cichoń, M., Vyas, J., Patel, N., Ghali, L., Cerio, R., Storey, A. and O'Toole, E. 2011. Axl promotes cutaneous squamous cell carcinoma survival through negative regulation of pro-apoptotic Bcl-2 family members. Journal of investigative dermatology. 131 (2), pp. 509-517. https://doi.org/10.1038/jid.2010.326

A tripolar current-steering stimulator ASIC for field shaping in deep brain stimulation

Valente, V., Demosthenous, A. and Bayford, R. 2011. A tripolar current-steering stimulator ASIC for field shaping in deep brain stimulation. IEEE Transactions on Biomedical Circuits and Systems. 6 (3), pp. 197-207. https://doi.org/10.1109/TBCAS.2011.2171036

New imaging mapping device for the detection and location of rectal cancer

Bayford, R., Borsic, A., Tizzard, A., Kantartzis, P., Liatsis, P. and Demosthenous, A. 2012. New imaging mapping device for the detection and location of rectal cancer. 13th International Conference on Electrical Impedance Tomography (EIT 2012). Tianjin, China 23 - 25 May 2012

Tracking conductivity variations in the absence of accurate state evolution models in electrical impedance tomography

Hashemzadeh, P., Sahota, V., Callaghan, M., El Dib, H., Tizzard, A., Svensson, L. and Bayford, R. 2010. Tracking conductivity variations in the absence of accurate state evolution models in electrical impedance tomography. in: 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE), 2010 IEEE. pp. 1-6

GREIT: a unified approach to 2D linear EIT reconstruction of lung images

Adler, A., Arnold, J., Bayford, R., Borsic, A., Brown, B., Dixon, P., Faes, T., Frerichs, I., Gagnon, H., Garber, Y., Grychtol, B., Hahn, G., Lionheart, W., Malik, A., Patterson, R., Stocks, J., Tizzard, A., Weiler, N. and Wolf, G. 2009. GREIT: a unified approach to 2D linear EIT reconstruction of lung images. Physiological Measurement. 30 (6), pp. S35-S55. https://doi.org/10.1088/0967-3334/30/6/S03

Dynamic electrical impedance tomography image reconstruction of neonate lung function based on linear Kalman filter techniques

El Dib, H., Tizzard, A. and Bayford, R. 2009. Dynamic electrical impedance tomography image reconstruction of neonate lung function based on linear Kalman filter techniques. in: Dössel, O. and Schlegel, W. (ed.) IFMBE Proceedings, World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany Munich, Germany Springer.

Development of a sensor network for dynamic boundary measurement in neonatal electrical impedance tomography (EIT)

Khor, J., Tizzard, A., Demosthenous, A. and Bayford, R. 2009. Development of a sensor network for dynamic boundary measurement in neonatal electrical impedance tomography (EIT). in: Dössel, O. and Schlegel, W. (ed.) IFMBE Proceedings, World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany Munich, Germany Springer.

Effects of warping finite element meshes for the forward model of the head in EIT

Tizzard, A., Bayford, R., Horesh, L., Yerworth, R. and Holder, D. 2004. Effects of warping finite element meshes for the forward model of the head in EIT. in: Nowakowski, A. (ed.) Proceedings of the XII International Conference of Electrical Bioimpedance & V Electrical Impedance Tomography Gdansk, Poland Gdansk University of Technology.

Validation of finite element mesh warping for improving the forward model in EIT of brain function

Tizzard, A. and Bayford, R. 2007. Validation of finite element mesh warping for improving the forward model in EIT of brain function. in: Scharfetter, H. and Merwa, R. (ed.) IFMBE Proceedings, Part II - 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography 2007 Graz, Austria Springer Verlag.

Reconstruction algorithms to monitor neonate lung function

Bayford, R., Kantartzis, P., Tizzard, A., Yerworth, R., Liatsis, P. and Demosthenous, A. 2007. Reconstruction algorithms to monitor neonate lung function. in: Scharfetter, H. and Mervwa, R. (ed.) IFMBE Proceedings, Part II - 13th International Conference on Electrical Bioimpedance and 8th Conference on Electrical Impedance Tomography 2007 Graz, Austria Springer Verlag.

Generation and performance of patient-specific forward models for breast imaging with EIT

Tizzard, A., Borsic, A., Halter, R. and Bayford, R. 2010. Generation and performance of patient-specific forward models for breast imaging with EIT. Journal of Physics: Conference Series. 224 (1), pp. 1-4. https://doi.org/10.1088/1742-6596/224/1/012034

A comparison study of electrodes for neonate electrical impedance tomography

Rahal, M., Khor, J., Demosthenous, A., Tizzard, A. and Bayford, R. 2009. A comparison study of electrodes for neonate electrical impedance tomography. Physiological Measurement. 30 (6), pp. 73-84. https://doi.org/10.1088/0967-3334/30/6/S05

Development of a neonate lung reconstruction algorithm using a wavelet AMG and estimated boundary form

Bayford, R., Kantartzis, P., Tizzard, A., Yerworth, R., Liatsis, P. and Demosthenous, A. 2008. Development of a neonate lung reconstruction algorithm using a wavelet AMG and estimated boundary form. Physiological Measurement. 29 (6), pp. S125-S138. https://doi.org/10.1088/0967-3334/29/6/S11

Generating accurate finite element meshes for the forward model of the human head in EIT

Tizzard, A., Horesh, L., Yerworth, R., Holder, D. and Bayford, R. 2005. Generating accurate finite element meshes for the forward model of the human head in EIT. Physiological Measurement. 26 (2), pp. S251-S262.

Solving the forward problem in electrical impedance tomography for the human head using IDEAS (integrated design engineering analysis software), a finite element modelling tool

Bayford, R., Gibson, A., Tizzard, A., Tidswell, T. and Holder, D. 2001. Solving the forward problem in electrical impedance tomography for the human head using IDEAS (integrated design engineering analysis software), a finite element modelling tool. Physiological Measurement. 22 (1), pp. 55-64.

Investigating the mechanism of deep brain stimulation using a dynamic complex model of the head incorporated with the complete model of electrode

Bayford, R., Tizzard, A., Yousif, N. and Liu, X. 2006. Investigating the mechanism of deep brain stimulation using a dynamic complex model of the head incorporated with the complete model of electrode. Clinical Neurophysiology. 117, pp. S219-S220.

Ectopic HCG beta may induce epithelialmensenchymal transition on human kera tinocytes in vitro and this could promote tumour progression and invasion.

Wen, S., Li, D., Ghali, L. and Iles, R. 2010. Ectopic HCG beta may induce epithelialmensenchymal transition on human kera tinocytes in vitro and this could promote tumour progression and invasion. Tumour Biology. 31 (S44).

GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state

Nadenla, S., Hazan, A., Ward, M., Harper, L., Moutasim, K., Bianchi, L., Naase, M., Ghali, L., Thomas, G., Prowse, D., Philpott, M. and Neill, G. 2011. GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state. PLoS ONE. 6 (5), pp. 1-13. https://doi.org/10.1371/journal.pone.0020271

Detection of cancer.

Bayford, R., Roitt, I., Rademacher, T., Demosthenous, A. and Iles, R. 2010. Detection of cancer.

Electric field characteristics of bipolar impedance sensors.

Kassanos, P., Bayford, R. and Demosthenous, A. 2009. Electric field characteristics of bipolar impedance sensors. 11th International Congress of the IUPESM - Medical Physics and Biomedical Engineering World Congress 2009 - for the benefit of the patient program. Munich, Germany 07 - 12 Sep 2009

A high output impedance current source for wideband bioimpedance measurements.

Hong, H., Bayford, R. and Demosthenous, A. 2009. A high output impedance current source for wideband bioimpedance measurements. 11th International Congress of the IUPESM - Medical Physics and Biomedical Engineering World Congress 2009 - for the benefit of the patient program.. Munich, Germany 07 - 12 Sep 2009

The use of EIT in the detection of regional lung dysfunction in prematurely born neonates.

Zifan, A., Liatsis, P. and Bayford, R. 2009. The use of EIT in the detection of regional lung dysfunction in prematurely born neonates. 11th International Congress of the IUPESM - Medical Physics and Biomedical Engineering World Congress 2009 - for the benefit of the patient program. Munich, Germany 07 - 12 Sep 2009

Electrochemical impedance detection of hCGbeta: preliminary results and analysis in the development of lab on a chip technology.

Bayford, R., Kassanos, P., Demosthenous, A. and Iles, R. 2009. Electrochemical impedance detection of hCGbeta: preliminary results and analysis in the development of lab on a chip technology. 42nd IUPAC Congress: Chemistry Solutions SECC.. Glasgow, Scotland, UK. 02 - 07 Aug 2009

Statistical analysis for brain EIT images using SPM.

Zhang, Y., Passmore, P., Yerworth, R. and Bayford, R. 2005. Statistical analysis for brain EIT images using SPM. Institute of Electrical and Electronics Engineers. pp. 60-67 https://doi.org/10.1109/MEDIVIS.2005.17

A human domain antibody and Lewisb glycoconjugate that inhibit binding of helicobacter pylori to Lewisb receptor and adhesion to human gastric epithelium

Younson, J., O'Mahony, R., Liu, H., Grant, S., Campion, C., Jennings, L., Vaira, D., Kelly, C., Roitt, I. and Holton, J. 2009. A human domain antibody and Lewisb glycoconjugate that inhibit binding of helicobacter pylori to Lewisb receptor and adhesion to human gastric epithelium. Journal of Infectious Diseases. 200 (10), pp. 1574-1582. https://doi.org/10.1086/644596

Designing a new generation of anti-hCG vaccines for cancer therapy

Delves, P., Iles, R., Roitt, I. and Lund, T. 2007. Designing a new generation of anti-hCG vaccines for cancer therapy. Molecular and Cellular Endocrinology. 260-26, pp. 276-281. https://doi.org/10.1016/j.mce.2006.02.018

Refocusing of B-cell responses following a single amino acid substitution in an antigen.

Dalla Chiesa, M., Martensen, P., Simmons, C., Porakishvili, N., Justesen, J., Dougan, G., Roitt, I., Delves, P. and Lund, T. 2001. Refocusing of B-cell responses following a single amino acid substitution in an antigen. Immunology. 103 (2), pp. 172-178. https://doi.org/10.1046/j.1365-2567.2001.01242.x

Tumour burden and Interleukin-2 (IL-2) dose affect the interaction between low-dose total body irradiation and Interleukin-2.

Safwat, A., Aggerholm, N., Roitt, I., Overgaard, J. and Hoklund, M. 2004. Tumour burden and Interleukin-2 (IL-2) dose affect the interaction between low-dose total body irradiation and Interleukin-2. European Journal of Cancer. 40 (9), pp. 1412-1417. https://doi.org/10.1016/j.ejca.2004.01.037

Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells.

Kvirkvelia, N., Vojnovic, I., Warner, T., Athie-Morales, V., Free, P., Rayment, N., Chain, B., Rademacher, T., Lund, T., Roitt, I. and Delves, P. 2002. Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells. Clinical & Experimental Immunology. 127 (2), pp. 263-269. https://doi.org/10.1046/j.1365-2249.2002.01718.x

Low dose total body irradiation augments the therapeutic effect of interleukin-2 in a mouse model for metastatic malignant melanoma.

Safwat, A., Aggerholm, N., Roitt, I., Overgaard, J. and Hoklund, M. 2003. Low dose total body irradiation augments the therapeutic effect of interleukin-2 in a mouse model for metastatic malignant melanoma. Journal of experimental therapeutics & oncology. 3 (4), pp. 161-168. https://doi.org/10.1046/j.1359-4117.2003.01093.x

Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis.

De Bernardis, F., Liu, H., O'Mahony, R., La Valle, R., Bartollino, S., Sandini, S., Grant, S., Brewis, N., Tomlinson, I., Basset, R., Holton, J., Roitt, I. and Cassone, A. 2007. Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis. Journal of Infectious Diseases. 195 (1), pp. 149-157. https://doi.org/10.1086/509891

Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy.

O'Mahony, R., Basset, C., Holton, J., Vaira, D. and Roitt, I. 2005. Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy. Elsevier. https://doi.org/10.1016/j.mimet.2004.11.020

Changes in the reproductive system of male mice immunized with a GnRH-analogue conjugated to mycobacterial hsp70

Hannesdottir, S., Han, X., Lund, T., Singh, M., Van Der Zee, R., Roitt, I. and Delves, P. 2004. Changes in the reproductive system of male mice immunized with a GnRH-analogue conjugated to mycobacterial hsp70. Reproduction: the official journal of the Society for the Study of Fertility. 128 (3), pp. 365-371. https://doi.org/10.1530/rep.1.00108

Innate immunity and pathogen-host interaction.

Basset, C., Holton, J., O'Mahony, R. and Roitt, I. 2003. Innate immunity and pathogen-host interaction. Vaccine. 21 (Supple), pp. S12-S23. https://doi.org/10.1016/S0264-410X(03)00195-6

Elimination of luteinizing hormone cross-reactive epitopes from human chorionic gonadotropin.

Porakishvili, N., Chiesa, M., Chikadze, N., Martensen, P., Justesen, J., Lund, T., Delves, P. and Roitt, I. 2002. Elimination of luteinizing hormone cross-reactive epitopes from human chorionic gonadotropin. Vaccine. 20 (16), pp. 2053-2059. https://doi.org/10.1016/S0264-410X(02)00051-8

Genes and IgG glycosylation in autoimmune and non-autoimmune strains of mice

Delves, P., Lund, T. and Roitt, I. 2002. Genes and IgG glycosylation in autoimmune and non-autoimmune strains of mice. Trends in Immunology. 23 (4), pp. 213-219. https://doi.org/10.1016/S1471-4906(02)02182-8

The human chorionic gonadotropin-ß arginine68 to glutamic acid substitution fixes the conformation of the C-terminal Peptide

Charrel-Dennis, M., Terrazzini, N., McBride, J., Martensen, P., Justesen, J., Berger, P., Lapthorn, A., Kelly, C., Roitt, I., Delves, P. and Lund, T. 2005. The human chorionic gonadotropin-ß arginine68 to glutamic acid substitution fixes the conformation of the C-terminal Peptide. Molecular Endocrinology. 19 (7), pp. 1803-1811. https://doi.org/10.1210/me.2004-0109

The major hormone-specific epitopes on human chorionic gonadotropin

Charrel-Dennis, M., Jackson, A., Lund, T., Lapthorn, A., Berger, P., Roitt, I. and Delves, P. 2004. The major hormone-specific epitopes on human chorionic gonadotropin. Journal of molecular endocrinology. 32 (2), pp. 571-581.

Immunochemical mapping of gonadotropin

Berger, P., Bidart, J., Delves, P., Dirnhofer, S., Hoermann, R., Isaacs, N., Jackson, A., Klonisch, T., Lapthorn, A., Lund, T., Mann, K., Roitt, I., Schwartz, S. and Wick, G. 1996. Immunochemical mapping of gonadotropin. Molecular and Cellular Endocrinology. 125 (1-2), pp. 33-43. https://doi.org/10.1016/S0303-7207(96)03943-3

New and emerging tomographic imaging techniques in medical and industrial applications. Introduction

Soleimani, M. and Bayford, R. 2009. New and emerging tomographic imaging techniques in medical and industrial applications. Introduction. Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences. 367 (1900), pp. 3017-3019.

Visualization of multidimensional and multimodal tomographic medical imaging data, a case study

Zhang, Y., Passmore, P. and Bayford, R. 2009. Visualization of multidimensional and multimodal tomographic medical imaging data, a case study. Philosophical Transactions of the Royal Society of London. A: Mathematical and Physical Sciences. 367 (1900), pp. 3121-3148. https://doi.org/10.1098/rsta.2009.0084

Comparison of a new integrated current source with the modified Howland circuit for EIT applications

Hong, H., Rahal, M., Demosthenous, A. and Bayford, R. 2009. Comparison of a new integrated current source with the modified Howland circuit for EIT applications. Physiological Measurement. 30 (10), pp. 999-1007. https://doi.org/10.1088/0967-3334/30/10/001

Generating surfaces for registration and warping FE meshes for the forward model in EIT of brain function.

Tizzard, A., Holder, D., Bayford, R. and International Federation for Medical and Biological Engineering 2005. Generating surfaces for registration and warping FE meshes for the forward model in EIT of brain function. Springer.

Effects of modelling layers and realistic geometry in reconstruction algorithms for EIT of brain function.

Liston, A., Bagshaw, A., Bayford, R., Tizzard, A., Tidswell, A., Dehghani, H. and Holder, D. 2003. Effects of modelling layers and realistic geometry in reconstruction algorithms for EIT of brain function. 4th Conference on Biomedical Applications of Electrical Impedance Tomography. Manchester, UK 23 - 25 Apr 2003 UMIST, Manchester, UK pp. 19 https://doi.org/10.5281/zenodo.17924

Modelling the effect of eye sockets in the human head using I-DEAS and its implication for imaging impedance change using Electrical Impedance Tomography.

Bayford, R., Gibson, A., Tizzard, A., Liston, A., Tidswell, A., Bagshaw, A. and Holder, D. 2001. Modelling the effect of eye sockets in the human head using I-DEAS and its implication for imaging impedance change using Electrical Impedance Tomography. Grimmes, S., Martinsen, O. and Bruvoll, H. (ed.) Oslo University of Oslo. pp. 391-396

Development of algorithms to image impedance changes inside the human head.

Bayford, R., Bagshaw, A., Liston, A., Tizzard, A. and Holder, D. 2002. Development of algorithms to image impedance changes inside the human head. The First Mummy Range Workshop on Electric Impedance Imaging. Colorado, US Colorado State University

Robustness of linear and nonlinear reconstruction algorithms for brain EITS.

Yerworth, R., Horesh, L., Bayford, R., Tizzard, A. and Holder, D. 2004. Robustness of linear and nonlinear reconstruction algorithms for brain EITS. Nowakowski, A., Wtorek, J., Bujnowski, A. and Janczulewicz, A. (ed.) Gdansk, Poland Gdansk University of Technology. pp. 499-502

Beyond the linear domain: the way forward in MFEIT reconstruction of the human head.

Horesh, L., Bayford, R., Yerworth, R., Tizzard, A., Ahadzi, G. and Holder, D. 2004. Beyond the linear domain: the way forward in MFEIT reconstruction of the human head. Nowakowski, A., Wtorek, J., Bujnowski, A. and Janczulewicz, A. (ed.) Gdansk, Poland Gdansk University of Technology. pp. 683-686

Laser modulation of angiogenic factor production by T-lymphocytes.

Agaiby, A., Ghali, L., Wilson, R. and Dyson, M. 2000. Laser modulation of angiogenic factor production by T-lymphocytes. Lasers in surgery and medicine. 26 (4), pp. 357-363. https://doi.org/10.1002/(SICI)1096-9101(2000)26:4<357::AID-LSM3>3.0.CO;2-O

An association between sebaceous carcinoma and microsatellite instability in immunosuppressed organ transplant recipients

Harwood, C., Swale, V., Bataille, V., Quinn, A., Ghali, L., Patel, S., Dove-Edwin, I., Cerio, R. and McGregor, J. 2001. An association between sebaceous carcinoma and microsatellite instability in immunosuppressed organ transplant recipients. Journal of investigative dermatology. 116 (2), pp. 246-253. https://doi.org/10.1046/j.1523-1747.2001.01233.x

Human β defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions

Chronnell, C., Ghali, L., Ali, R., Quinn, A., Holland, D., Bull, J., Cunliffe, W., McKay, I., Philpott, M. and Müller-Röver, S. 2001. Human β defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions. Journal of investigative dermatology. 117 (5), pp. 1120-1125. https://doi.org/10.1046/j.0022-202x.2001.01569.x

Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus

Jackson, S., Ghali, L., Harwood, C. and Storey, A. 2002. Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus. British journal of cancer. 87 (3), pp. 319-323. https://doi.org/10.1038/sj.bjc.6600431

Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization

Bloor, B., Tidman, N., Leigh, I., Odell, E., Dogan, B., Wollina, U., Ghali, L. and Waseem, A. 2003. Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization. American Journal of Pathology. 162 (3), pp. 963-975.

The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin

Akgul, B., Garcia-Escudero, R., Ghali, L., Pfister, H., Fuchs, P., Navsaria, H. and Storey, A. 2005. The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin. Cancer Research. 65 (6), pp. 2216-2223. https://doi.org/10.1158/0008-5472.CAN-04-1952

LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome.

Ong, C., O'Toole, E., Ghali, L., Malone, M., Smith, V., Callard, R. and Harper, J. 2004. LEKTI demonstrable by immunohistochemistry of the skin: a potential diagnostic skin test for Netherton syndrome. British journal of dermatology. 151 (6), pp. 1253-1257. https://doi.org/10.1111/j.1365-2133.2004.06180.x

Safety and efficacy of 5% imiquimod cream for the treatment of skin dysplasia in high-risk renal transplant recipients: randomized, double-blind, placebo-controlled trial

Brown, V., Atkins, C., Ghali, L., Cerio, R., Harwood, C. and Proby, C. 2005. Safety and efficacy of 5% imiquimod cream for the treatment of skin dysplasia in high-risk renal transplant recipients: randomized, double-blind, placebo-controlled trial. Archives of Dermatology. 141 (8), pp. 985-993.

Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours

Green, J., Ikram, M., Vyas, J., Patel, N., Proby, C., Ghali, L., Leigh, I., O'Toole, E. and Storey, A. 2006. Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours. British journal of cancer. 94 (10), pp. 1446-1451.

Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria.

Leverrier, S., Bergamaschi, D., Ghali, L., Ola, A., Warnes, G., Akgul, B., Blight, K., Garcia-Escudero, R., Penna, A., Eddaoudi, A. and Storey, A. 2007. Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria. Apoptosis: an international journal on programmed cell death. 12 (3), pp. 549-560. https://doi.org/10.1007/s10495-006-0004-1

Role for WNT16B in human epidermal keratinocyte proliferation and differentiation

Teh, M., Blaydon, D., Ghali, L., Briggs, V., Edmunds, S., Pantazi, E., Barnes, M., Leigh, I., Kelsell, D. and Philpott, M. 2007. Role for WNT16B in human epidermal keratinocyte proliferation and differentiation. Journal of Cell Science. 120 (2), pp. 330-339.

Longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of NOS1 and elastin in uncomplicated diverticular disease.

Golder, M., Burleigh, D., Ghali, L., Feakins, R., Lunniss, P., Williams, N. and Navsaria, H. 2007. Longitudinal muscle shows abnormal relaxation responses to nitric oxide and contains altered levels of NOS1 and elastin in uncomplicated diverticular disease. Colorectal disease. 9 (3), pp. 218-228.

HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes.

Akgul, B., Ghali, L., Davies, D., Pfister, H., Leigh, I. and Storey, A. 2007. HPV8 early genes modulate differentiation and cell cycle of primary human adult keratinocytes. Clinical and experimental dermatology. 16 (7), pp. 590-599.

Granulosa cell survival and proliferation are altered in polycystic ovary syndrome

Das, M., Djahanbakhch, O., Hacihanefioglu, B., Saridogan, E., Ikram, M., Ghali, L., Raveendran, M. and Storey, A. 2008. Granulosa cell survival and proliferation are altered in polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism. 93 (3), pp. 881-887. https://doi.org/10.1210/jc.2007-1650

GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes

Neill, G., Harrison, W., Ikram, M., Williams, T., Bianchi, L., Nadenla, S., Green, J., Ghali, L., Frischauf, A., O'Toole, E., Aberger, F. and Philpott, M. 2008. GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes. Carcinogenesis. 29 (4), pp. 738-746. https://doi.org/10.1093/carcin/bgn037

A low budget luminometer for sensitive chemiluminescent immunoassays

Porakishvili, N., Fordham, J., Charrel-Dennis, M., Delves, P., Lund, T. and Roitt, I. 2000. A low budget luminometer for sensitive chemiluminescent immunoassays. Journal of Immunological Methods. 234 (1-2), pp. 35-42. https://doi.org/10.1016/S0022-1759(99)00198-2

The immune system: second of two parts

Delves, P. and Roitt, I. 2000. The immune system: second of two parts. New England Journal of Medicine. 343 (2), pp. 108-117.

The immune system: first of two parts

Delves, P. and Roitt, I. 2000. The immune system: first of two parts. New England Journal of Medicine. 343 (1), pp. 37-49.

Future prospects for vaccines to control fertility

Delves, P., Lund, T. and Roitt, I. 2002. Future prospects for vaccines to control fertility. Trends in Immunology. 23 (4), pp. 220-221. https://doi.org/10.1016/S1471-4906(02)02183-X

Antifertility vaccines

Delves, P., Lund, T. and Roitt, I. 2002. Antifertility vaccines. Trends in Immunology. 23 (4), pp. 213-219. https://doi.org/10.1016/S1471-4906(02)02182-8

Vaccines for the control of reproduction - status in mammals, and aspects of comparative interest.

Delves, P. and Roitt, I. 2005. Vaccines for the control of reproduction - status in mammals, and aspects of comparative interest. Developments in Biologicals. 121, pp. 265-273.

Two-dimensional finite element modelling of the neonatal head

Gibson, A., Bayford, R. and Holder, D. 2000. Two-dimensional finite element modelling of the neonatal head. Physiological Measurement. 21 (1), pp. 45-52. https://doi.org/10.1088/0967-3334/21/1/306

Validation of a 3D reconstruction algorithm for EIT of human brain function in a realistic head-shaped tank

Tidswell, A., Gibson, A., Bayford, R. and Holder, D. 2001. Validation of a 3D reconstruction algorithm for EIT of human brain function in a realistic head-shaped tank. Physiological Measurement. 22 (1), pp. 177-185. https://doi.org/10.1088/0967-3334/22/1/321

Electrical impedance tomography of human brain activity with a two-dimensional ring of scalp electrodes

Tidswell, A., Gibson, A., Bayford, R. and Holder, D. 2001. Electrical impedance tomography of human brain activity with a two-dimensional ring of scalp electrodes. Physiological Measurement. 22 (1), pp. 167-175. https://doi.org/10.1088/0967-3334/22/1/320

A feasibility study of remote monitoring of asthmatic patients.

Steel, S., Lock, S., Johnson, N., Martinez, Y., Marquilles, E. and Bayford, R. 2002. A feasibility study of remote monitoring of asthmatic patients. Journal of telemedicine and telecare. 8 (5), pp. 290-296.

Design and performance of the UCLH mark 1b 64 channel electrical impedance tomography (EIT) system, optimized for imaging brain function

Yerworth, R., Bayford, R., Cusick, G., Conway, M. and Holder, D. 2002. Design and performance of the UCLH mark 1b 64 channel electrical impedance tomography (EIT) system, optimized for imaging brain function. Physiological Measurement. 23 (1), pp. 149-158. https://doi.org/10.1088/0967-3334/23/1/314

A multi-shell algorithm to reconstruct EIT images of brain function

Liston, A., Bayford, R., Tidswell, A. and Holder, D. 2002. A multi-shell algorithm to reconstruct EIT images of brain function. Physiological Measurement. 23 (1), pp. 105-119. https://doi.org/10.1088/0967-3334/23/1/310

A comparison of headnet electrode arrays for electrical impedance tomography of the human head

Tidswell, A., Bagshaw, A., Holder, D., Yerworth, R., Eadie, L., Murray, S., Morgan, L. and Bayford, R. 2003. A comparison of headnet electrode arrays for electrical impedance tomography of the human head. Physiological Measurement. 24 (2), pp. 527-544. https://doi.org/10.1088/0967-3334/24/2/363

Electrical impedance tomography spectroscopy (EITS) for human head imaging

Yerworth, R., Bayford, R., Brown, B., Milnes, P., Conway, M. and Holder, D. 2003. Electrical impedance tomography spectroscopy (EITS) for human head imaging. Physiological Measurement. 24 (2), pp. 477-489. https://doi.org/10.1088/0967-3334/24/2/358

The application of the generalized vector sample pattern matching method for EIT image reconstruction

Dong, G., Bayford, R., Gao, S., Saito, Y., Yerworth, R., Holder, D. and Yan, W. 2003. The application of the generalized vector sample pattern matching method for EIT image reconstruction. Physiological Measurement. 24 (2), pp. 449-466. https://doi.org/10.1088/0967-3334/24/2/356

Neuromagnetic field strength outside the human head due to impedance changes from neuronal depolarization

Ahadzi, G., Liston, A., Bayford, R. and Holder, D. 2004. Neuromagnetic field strength outside the human head due to impedance changes from neuronal depolarization. Physiological Measurement. 25 (1), pp. 365-378. https://doi.org/10.1088/0967-3334/25/1/040

The spatial resolution improvement of EIT images by GVSPM-FOCUSS algorithm

Dong, G., Liu, H., Bayford, R., Yerworth, R., Gao, S., Holder, D. and Yan, W. 2004. The spatial resolution improvement of EIT images by GVSPM-FOCUSS algorithm. Physiological Measurement. 25 (1), pp. 209-225. https://doi.org/10.1088/0967-3334/25/1/027

The effect of layers in imaging brain function using electrical impedance tomograghy

Liston, A., Bayford, R. and Holder, D. 2004. The effect of layers in imaging brain function using electrical impedance tomograghy. Physiological Measurement. 25 (1), pp. 143-158. https://doi.org/10.1088/0967-3334/25/1/022

Spatial resolution improvement of 3D EIT images by the shrinking sLORETA-FOCUSS algorithm

Dong, G., Liu, H., Bayford, R., Yerworth, R., Schimpf, P. and Yan, W. 2005. Spatial resolution improvement of 3D EIT images by the shrinking sLORETA-FOCUSS algorithm. Physiological Measurement. 26 (2), pp. S199-S208. https://doi.org/10.1088/0967-3334/26/2/019

Multi-frequency electrical impedance tomography (EIT) of the adult human head: initial findings in brain tumours, arteriovenous malformations and chronic stroke, development of an analysis method and calibration

Romsauerova, A., McEwan, A., Horesh, L., Yerworth, R., Bayford, R. and Holder, D. 2006. Multi-frequency electrical impedance tomography (EIT) of the adult human head: initial findings in brain tumours, arteriovenous malformations and chronic stroke, development of an analysis method and calibration. Physiological Measurement. 27 (5), pp. S147-S161. https://doi.org/10.1088/0967-3334/27/5/S13

Factors limiting the application of electrical impedance tomography for identification of regional conductivity changes using scalp electrodes during epileptic seizures in humans

Fabrizi, L., Sparkes, M., Horesh, L., Abascal, J., McEwan, A., Bayford, R., Elwes, R., Binnie, C. and Holder, D. 2006. Factors limiting the application of electrical impedance tomography for identification of regional conductivity changes using scalp electrodes during epileptic seizures in humans. Physiological Measurement. 27 (5), pp. S163-S174. https://doi.org/10.1088/0967-3334/27/5/S14

Design and calibration of a compact multi-frequency EIT system for acute stroke imaging

McEwan, A., Romsauerova, A., Yerworth, R., Horesh, L., Bayford, R. and Holder, D. 2006. Design and calibration of a compact multi-frequency EIT system for acute stroke imaging. Physiological Measurement. 27 (5), pp. S199-S210. https://doi.org/10.1088/0967-3334/27/5/S17

Validation of a finite-element solution for electrical impedance tomography in an anisotropic medium

Abascal, J., Arridge, S., Lionheart, W., Bayford, R. and Holder, D. 2007. Validation of a finite-element solution for electrical impedance tomography in an anisotropic medium. Physiological Measurement. 28 (7), pp. S129-S140. https://doi.org/10.1088/0967-3334/28/7/S10

Use of statistical parametric mapping (SPM) to enhance electrical impedance tomography (EIT) image sets.

Yerworth, R., Zhang, Y., Tidswell, A., Bayford, R. and Holder, D. 2007. Use of statistical parametric mapping (SPM) to enhance electrical impedance tomography (EIT) image sets. Physiological Measurement. 28 (7), pp. S141-S151. https://doi.org/10.1088/0967-3334/28/7/S11

The peri-electrode space is a significant element of the electrode-brain interface in deep brain stimulation: a computational study

Yousif, N., Bayford, R., Bain, P. and Liu, X. 2007. The peri-electrode space is a significant element of the electrode-brain interface in deep brain stimulation: a computational study. Brain Research Bulletin. 74 (5), pp. 361-368. https://doi.org/10.1016/j.brainresbull.2007.07.007

Quantifying the effects of the electrode-brain interface on the crossing electric currents in deep brain recording and stimulation

Yousif, N., Bayford, R., Wang, S. and Liu, X. 2008. Quantifying the effects of the electrode-brain interface on the crossing electric currents in deep brain recording and stimulation. Neuroscience. 152 (3), pp. 683-691. https://doi.org/10.1016/j.neuroscience.2008.01.023

13th International conference on electrical bioimpedance and 8th conference on electrical impedance tomography

Bayford, R. and Scharfetter, H. 2008. 13th International conference on electrical bioimpedance and 8th conference on electrical impedance tomography. Physiological Measurement. 29 (6), pp. E1-E2. https://doi.org/10.1088/0967-3334/29/6/E01

The influence of reactivity of the electrode-brain interface on the crossing electric current in therapeutic deep brain stimulation

Yousif, N., Bayford, R. and Liu, X. 2008. The influence of reactivity of the electrode-brain interface on the crossing electric current in therapeutic deep brain stimulation. Neuroscience. 156 (3), pp. 597-606. https://doi.org/10.1016/j.neuroscience.2008.07.051

Comparison of methods for optimal choice of the regularization parameter for linear electrical impedance tomography of brain function

Abascal, J., Arridge, S., Bayford, R. and Holder, D. 2008. Comparison of methods for optimal choice of the regularization parameter for linear electrical impedance tomography of brain function. Physiological Measurement. 29 (11), pp. 1319-1334. https://doi.org/10.1088/0967-3334/29/11/007

Gonadotropins and prostate cancer: revisited.

Thwaini, A., Naase, M., Chinegwundon, F., Baithun, S., Ghali, L., Shergill, I. and Iles, R. 2006. Gonadotropins and prostate cancer: revisited. Urologia internationalis. 77 (4), pp. 289-296. https://doi.org/10.1159/000096330

Towards the development of an electrochemical biosensor for hCGβ detection

Kassanos, P., Iles, R., Bayford, R. and Demosthenous, A. 2008. Towards the development of an electrochemical biosensor for hCGβ detection. Physiological Measurement. 29 (6), pp. S241-S254. https://doi.org/10.1088/0967-3334/29/6/S21

Task based visualization of 5D brain EIT data

Zhang, Y., Passmore, P. and Bayford, R. 2009. Task based visualization of 5D brain EIT data. SAC09: The 2009 ACM Symposium on Applied Computing. Honolulu Hawaii, USA 08 - 12 Mar 2009 New York Association for Computing Machinery (ACM). pp. 831-835 https://doi.org/10.1145/1529282.1529459

Improving the finite element forward model of the human head by warping using elastic deformation

Tizzard, A. and Bayford, R. 2007. Improving the finite element forward model of the human head by warping using elastic deformation. Physiological Measurement. 28 (7), pp. 163-182. https://doi.org/10.1088/0967-3334/28/7/S13

Smooth muscle cholinergic denervation hypersensitivity in diverticular disease.

Ghali, L., Belai, A., Burleigh, D. and Golder, M. 2003. Smooth muscle cholinergic denervation hypersensitivity in diverticular disease. The Lancet. 361 (9373), pp. 1945-1951. https://doi.org/10.1016/S0140-6736(03)13583-0

Epidermal and hair follicle progenitor cells express melanoma-associated chondroitin sulfate proteoglycan core protein

Ghali, L., Wong, S., Tidman, N., Quinn, A., Philpott, M. and Leigh, I. 2004. Epidermal and hair follicle progenitor cells express melanoma-associated chondroitin sulfate proteoglycan core protein. Journal of investigative dermatology. 122 (2), pp. 433-442. https://doi.org/10.1046/j.0022-202X.2004.22207.x

A comparison of techniques to optimize measurement of voltage changes in electrical impedance tomography by minimizing phase shift errors

Bayford, R., Eadie, L., Fitzgerald, A. and Holder, D. 2002. A comparison of techniques to optimize measurement of voltage changes in electrical impedance tomography by minimizing phase shift errors. IEEE Transactions on Medical Imaging. 21 (6), pp. 668-675. https://doi.org/10.1109/TMI.2002.800577

Bioimpedance; tomography (electrical impedance tomography).

Bayford, R. 2006. Bioimpedance; tomography (electrical impedance tomography). Annual Review of Biomedical Engineering. 8 (1), pp. 63-91. https://doi.org/10.1146/annurev.bioeng.8.061505.095716

Using the GRID to improve the computation speed of electrical impedance tomography (EIT) reconstruction algorithms

Bayford, R., Fritschy, J., Holder, D. and Horesh, L. 2005. Using the GRID to improve the computation speed of electrical impedance tomography (EIT) reconstruction algorithms. Physiological Measurement.

Use of anisotropic modelling in electrical impedance tomography: description of method and preliminary assessment of utility in imaging brain function in the adult human head

Abascal, J., Arridge, S., Atkinson, D., Horesh, R., Fabrizi, L., De Lucia, M., Horesh, L., Bayford, R. and Holder, D. 2008. Use of anisotropic modelling in electrical impedance tomography: description of method and preliminary assessment of utility in imaging brain function in the adult human head. NeuroImage. 43 (2), pp. 258-268. https://doi.org/10.1016/j.neuroimage.2008.07.023

The use of a European telemedicine system to examine the effects of pollutants and allergens on asthmatic respiratory health

Crabbe, H., Barber, A., Bayford, R., Hamilton, R., Jarrett, D. and Machin, N. 2004. The use of a European telemedicine system to examine the effects of pollutants and allergens on asthmatic respiratory health. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2004.04.045

FOXM1 is a downstream target of Gli1 in basal cell carcinomas

Teh, M., Wong, S., Neill, G., Ghali, L., Philpott, M. and Quinn, A. 2002. FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Research. 62 (16), pp. 4773-4780.

Loss of protein kinase calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma

Ghali, L., Green, J., Ikram, M. and Neill, G. 2003. Loss of protein kinase calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma. Cancer Research. 63 (15), pp. 4692-4697.

EIT images with improved spatial resolution using a realistic head model

Dong, G., Bayford, R., Liu, H., Zhou, Y. and Yan, W. 2006. EIT images with improved spatial resolution using a realistic head model. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. New York, NY, USA 31 Aug - 03 Sep 2006 IEEE. pp. 1134-1137 https://doi.org/10.1109/IEMBS.2006.259794

Dynamic modelling of electrical current distribution in the deep structure of the brain

Bayford, R., Tizzard, A. and Liu, X. 2005. Dynamic modelling of electrical current distribution in the deep structure of the brain. in: The 3rd IEE International Seminar on Medical Applications of Signal Processing 2005 (Ref. No. 2005-1119) London,UK The Institution of Engineering and Technology (IET).

Applications of GRID in clinical neurophysiology and electrical impedance tomography of brain function

Fritschy, J., Horesh, L., Holder, D. and Bayford, R. 2005. Applications of GRID in clinical neurophysiology and electrical impedance tomography of brain function. Solomonides, T., McClatchey, R., Breton, V., Legré, Y., and Nørager, S. (ed.) Healthgrid 2005: 3rd annual conference of the Healthgrid association. Oxford, UK 2005 IOS Press. pp. 138-145

Visualization and post-processing of 5D Brain Images

Zhang, Y., Passmore, P. and Bayford, R. 2005. Visualization and post-processing of 5D Brain Images. 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Shanghai, China 01 - 04 Sep 2005 IEEE. pp. 1083-1086 https://doi.org/10.1109/IEMBS.2005.1616607

Electrical impedance tomography of human brain function using reconstruction algorithms based on the finite element method

Tizzard, A., Bagshaw, A., Bayford, R. and Liston, A. 2003. Electrical impedance tomography of human brain function using reconstruction algorithms based on the finite element method. NeuroImage. 20 (2), pp. 752-764. https://doi.org/10.1016/S1053-8119(03)00301-X

Three-dimensional electrical impedance tomography of human brain activity

Tidswell, A., Gibson, A., Bayford, R. and Holder, D. 2001. Three-dimensional electrical impedance tomography of human brain activity. NeuroImage. 13 (2), pp. 283-294. https://doi.org/10.1006/nimg.2000.0698

Application of constrained optimisation techniques inelectrical impedance tomography

Bayford, R. 1994. Application of constrained optimisation techniques inelectrical impedance tomography. PhD thesis Middlesex University School of Science and Technology